Which would you have the most confidence in A randomized clinical trial with 15K subjects or a randomized clinical trial with 5000 subjects?
15,000
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A p value less than .05 is considered statistically significant. Would a p value of .001 be statistically significant?
Yes, it is even more statistically significant.
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What is the unit for length, mass, volume in science?
Mass = grams, length = meters, volume = liters or cubic centimeters
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What is the importance of statistical analysis?
It can be used to support or reject a hypothesis and also determine if differences are real or by chance.
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Define correlation? Is correlation causation?
A consistent relationship between two variables. No
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Which microscope can be used for living organisms?
Compound light microscope
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Would this be considered a hypothesis: long term pot smokers have fewer problem solving skills than non drug users.
Yes
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When making an epidemiological study, which of the following should you avoid? Opinions, small sample size, complexity of disease, not having randomized subjects, no placebo or control.
Avoid all of those things. If you don’t’ understand the complexity of the disease, you might make assumptions.
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Define hypothesis
Educated guess to explain an observation. It must be testable and may or may not be proven correct.
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Define statistical significance.
A measure of confidence that results obtain are real and not due to chance. P value of .05
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List reliable sources of information.
Most to least reliable : scientific journals, articles written by a scientist in a magazine, journal articles, public opinion, your gossip friend.
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Define Independent variable
Only 1 factor is changed in a controlled experiment
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If you are testing the new corona virus pill, you have a group that gets the pill and one that gets a placebo sugar pill. Why do you give group 2 a sugar pill?
Both groups need to be doing the same behavior. If one group doesn’t take a pill does that affect their mental and physical behaviors?
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What are the steps in a scientific study?
Observation, generate questions, research generate a hypothesis, test hypothesis, collect data, draw conclusions
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What is an experimental group and a control group?
Control group is the group that is not receiving the independent variable. The experimental group does.
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What is the EARLIEST step in the scientific process?
Asking a question about an observation
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What is peer review and why is it important?
It allows other scientists to verify your experiment and data as accurate, it allows other scientists to learn from and alter your experiment to move further in research, it allows other scientists to repeat your experiment.
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Put in correct order (read literature, experiment, ask questions, conclusion, form a hypothesis.
Using Infographic 2.1, Which elements are isotopes and which are ions?
Carbon is a isotope (hydrogen is not usually considered one and wont’ be an answer on the the test, magnesium is an ion
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Y/N do enzymes lower activation energy for a reaction? Do they speed up a reaction?
Yes yes
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Using infographic 4.1, Label A-D.
A substrate, B enzyme, C enzyme substrate complex, D product
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Cell surface markers are important. What are they made of?
They are the Flags on the cell surface that tell other cells that they are your cells and a specific tissue. They are glycoproteins and are part protein and part sugar.
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Use infographic 3.6. Label each one.
A simple diffusion, B facilitated diffusion, C active transport
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Put in correct order tissue, cell, organism, organ, organ system,
Simplest to complex, cell, tissue, organ, organ system, organism, organ donor (haha)
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What do facilitated diffusion and simple diffusion have in common?
They are both moving molecules, not water from a higher to a lower concentration. They do not need energy to take place.
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What does hypotonic, isotonic and hypertonic mean? If I had a fish, bacteria, and plant that lived in a pond, and I put it into pure deionized water, what would happen to each organism’s cells
Hypo is when a cell is placed in pure water. Iso, the same concentration inside as outside the cell, hyper more concentrated solutions are outside the cell and water will leave the cell to dilute the concentration. All will take in water since they were placed into a HYPOtonic solution. It may kill the fish and rupture the gill cells, but the plant and bacteria will be find due to the cell wall.
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What is the difference between gram negative and gram positive bacteria?
Gram positive are killed by penicillin where gram negative are not.
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Use infographic 3.4. Label A, B, C.
A is hypo, B is hyper, C is iso
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Fill out the chart below.
\ Prokaryotic Eukaryotic
Size (Small or Large)
Cell Membrane (Y/N)
Membrane-bound Organelles (Y/N)
Nucleus (Y/N)
Prokaryotic Eukaryotic
Size (Small or Large) Small Large
Cell Membrane (Y/N) Yes Yes
Membrane-bound Organelles (Y/N) No Yes
Nucleus (Y/N) No Yes
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(Please check Study guide for table)
Which are true?
S.Diffusion F.Diffusion A.Transport
M.S. Small Either Either
Philic Or Phobic Phobic Phobic Either
Concentration H to L H to L L to H
Transport Protein No Yes Yes
Energy Required No No Yes
\ All are True
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Before refrigeration, people salted food to preserve it. Why?
Water will leave fungal and bacterial cells that may be on the food. Over time those cells will die because osmosis will force water out of their cells.
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What organelles are used, in order, to make a protein?
Nucleus, rough ER, Golgi, cell membrane
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Y/N
Does using algae as a biofuel burn the same amount of CO2 as it took in?
Does it release more pollutants?
Is there enough CO2 in the atmosphere to make enough algae biofuel equal to the fossil fuels we use right now?
Can biofuels generate electricity?
Algae release just as much CO2 as fossil fuels, but growing the algae takes CO2 out of the atmosphere so it is closer to being carbon neutral. It also releases fewer toxic chemicals than fossil fuels do. We cannot grow algae fast enough to meet our fuel needs right now. Me must use alternative energy sources such as wind, water, solar, or hydrothermal to make up for it. Algal biofuel can be used to make energy same is fossil fuels can.
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What happens to the chemical energy produced during photosynthesis?
It is stored as glucose, it is also used to make cell parts, grow fruit, and carry out the Calvin cycle,
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Use infographic 5.3 Which graph represent the effect of temperature on photosynthesis? Which graph shows the light intensity and speed of photosynthesis?
1 is temperature, 2 is light intensity,
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What happens to plants in the absence of sunlight?
The Calvin cycle can still take place as long as there is glucose stored (as a potato stores glucose for the plant), plants will carry out the Calvin cycle as long as there is reserved ATP. Plants can still carry out cell respiration which is the converting of sugars and fats into ATP.
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Can plants release the energy created from glucose during photosynthesis?
No, photosynthesis can only make the glucose, not break it down for energy. That is cell resp.
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What is the end product of the Calvin cycle?
Glucose
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What is the order of photosynthesis?
1) Photons of light are absorbed by chlorophyll reflects green light
2) Water molecules are absorbed and then split giving off o2 gas
3) Glucose is produced
4) Electrons from the split water help fuel the Calvin cycle along with 9 ATP
5) CO2 is absorbed
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What color pigments does chlorophyll absorb and reflect?
Reflects green, absorbs other, but mostly absorbs reds and blues
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Why are autotrophs useful?
They give us oxygen, food, remove CO2 from the air, and can make us fuel
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Use infographic 5.6. What is going on in each test tube as far as cellular respiration and photosynthesis? A is kept in the dark, and B is kept in sunlight.
A is in the dark and only carrying out cell respiration. B is carrying out BOTH cell respiration AND photosynthesis, C is the control tub.
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How is water important in photosynthesis?
It provides the hydrogen ions to help run the Calvin cycle
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What are the products of photosynthesis?
The products are the reactants of cell respiration.
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What is the BMI for an obese person, an overweight person and a healthy weight person?
30 and over is obese, 19-24 is healthy, 25-29 is overweight
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Why do you breathe heavily after exercise?
To try to get muscle cells back into aerobic respiration –cell respiration and away from lactic acid fermentation
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Where does the CO2 that we breathe out come from? (which organelle?)
Mitochondrion
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Where does glycolysis, cell respiration and lactic acid fermentation take place in the cell?
Glycolysis AND fermentation are in the cytoplasm, cell resp in the mitochondrion
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What can a person do to help contribute to a calorie imbalance and lose weight?
Move more (called NEAT- Non Exercise Activity Thermogenics), fidget, exercise, reduced calories, more quality sleep,
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How many calories are in 10 grams of fat? Protein? Carbs?
90 from fat, 40 from protein, 40 from carbs
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Does BMI take into account, gender, athleticism, or frame size?
NOPE
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List the order of cellular respiration
Glycolysis, citric acid cycle (AKA KREBS), ETC
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What is the correct formula for cell respiration?
C6H12O6 + 6O2 → 6CO2 + 6H2O + ATP energy
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What are the main reasons for cancer to develop and progress?
Oncogenes, mutated tumor suppressor genes
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How might a person know if they may have inherited the BRCA1 gene?
Without testing, they can look at a family history of women having early breast cancer AND ovarian cancer at an early age.
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How many chromosomes do people have? What is the chromosome of a female? How many chromosomes are in sperm and egg?
46, XX, 23
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List the order of the cell cycle.
IPMATC
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When would a cell undergo mitosis?
Dead cells being replaced, injury, tree branches growing, embryo growing
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When is cell division needed?
Replacing blood cells, growth of a body, damage to cells by injuries
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What is the end result of cytokinesis and the end result of meiosis?
2 diploid daughter cells that are genetically identical to parent cell, 4 haploid cells that are genetically different from parent cell
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What happens in prophase 1 to ensure genetic diversity?
Crossing over of non-sister chromatids
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Is cancer too much cell division?
Yes
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How many autosome pairs do humans have?
22
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Which is Mitosis, which is meiosis?
Which is Mitosis, which is meiosis?
46 to 23 Meiosis
46 to 46 Mitosis
2N to N meiosis
N-N mitosis
Germ Cell to gamete meiosis
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Why is DNA replication said to be semiconservative?
Each new DNA strand has 1 part of the old strand
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When it comes to STR’s how are we different?
In the number of STR’s we have. We all have 15 different ones, but how many of each is different.
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Is all you DNA identical in each cell?
Yes, except for gamete
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If you have AAAGGGTTTCCC, what is the complement strand?
TTTCCCAAAGGG
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Where are STR’s located?
On non-coding sections of DNA
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What is the “coding” region of DNA?
Where the DNA has a protein sequence on a certain part of a chromosome
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What is a DNA profile?
A unique banding pattern seen on a gel electrophoresis that corresponds to the STRs on DNA
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If a transgenic cow can make human insulin, what will the DNA be like in the cow? Will every cell have the insulin gene?
Yes
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If the DNA codon is AAA, what is the mRNA codon? What is the tRNA codon? What is the amino acid?
DNA = AAA, mRNA = UUU, tRNA = AAA, amino acid is lysine
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Be able to identify the types of chromosome mutations.
These are labeled on the picture in the study guide.