Histology - Old exams

Regarding connective tissue

1. It is derived from the mesoderm of the embryo layer

2. Composed mainly by epithelial cells and extracellular matrix

3. One of its function is to secrete substance

It is derived from the mesoderm of the embryo layer

Immunohistochemical technique

1. Requires precipitation of heavy metal stain tissue

2. Use fluorescence labeled antibody to identify macromolecules and glycogen

3. More precise than histological staining

Use fluorescence labeled antibody to identify macromolecules and glycogen

What technique to identify the presence of collagen fibers in a tissue?

1. PAS

2. OIL RED

3. Masson's trichrome staining

4. None

Masson's trichrome staining

Lysosome

1. Contain hydrophilic enzyme that digest macromolecules, phagocyte

microorganisms and is in the cytoplasm

2. Contain hydrolytic enzymes

3. Are organelles essentials for protein synthesis

Contain hydrophilic enzyme that digest macromolecules, phagocyte microorganisms and is in the cytoplasm

Epithelial tissue. INCORRECT ONE

1. Enriched tissue and the cells have polyhedral shape

2. Rest on the basement membrane and are avascular

3. Express cytokeratins as intermediate filaments

4. The cells are separated by abundant extracellular matrix

The cells are separated by abundant extracellular matrix

Choose the correct one

1. Microvillis have an internal structure with a complex of microtubules with 9+2 pairs

2. Cilia are long and mobile projection in response to ATP

3. The tight, anchoring, and gap junction are lateral specialization of the cell membrane

4. B & C

B & C

What specialization of the lateral cell membrane in the spinous layer of the epidermis is predominant?

1. No connection between cells

2. Gap junction and hemidesmosomes

3. Desmosomes

4. Occlusive junction

Desmosomes

adipose tissue. INCORRECT

1. Brown adipose tissue due to the weak vascularization and few mitochondrias with

the cytochrome

2. White adipocyte has lipid vacuole in their cell

3. Is a type of CT representing the main body energy store

4. White and brown adipose tissues differ in their morphology, color, distribution,

vascularity and metabolism act

Brown adipose tissue due to the weak vascularization and few mitochondrias with

the cytochrome

Hyaline cartilage.

1. Very similar to elastic cartilage except that lattes have elastic fibers

2. Hyaline is most abundant in the body

3. Helps to mold bones during embryo development and the epiphyseal plate during

bone growth

4. All are correct

All are correct

INCORRECT

1. Osteogenic or osteoprogenitor cells derived from mesenchymal cells and

differentiate into osteoblast

2. Osteoclast multinucleated cell form mononuclear phagocyte system and bone

resorption

3. The growth of long bones depends on the epiphyseal plate

4. Most of the flat bones develop by endochondral or indirect ossification

Most of the flat bones develop by endochondral or indirect ossification

Endocrine gland

1. Characterized by contained duct leading to secretion product

2. Salivary gland is a mix endocrine gland

3. Release secretory product directly into the blood

4. Goblet cells are an example of unicellular endocrine gland

Release secretory product directly into the blood

Type of gland that release a small amount of cytoplasm with the nucleus at the periphery

1. Apocrine

2. Holocrine

3. Merocrine

4. Endocrine

Apocrine

Skeletal muscle fibers

1. are multinucleated cells with nucleus at the periphery

2. epimysium surrounds the whole muscle while endomysium surrounds muscle fibers

3. fibers contain thin myofilament, actin, myosin

4. all

all

To identify the presence of collagen in a tissue which technique would you use?

1. PAS

2. Oil red

3. Masson trichrome

4. None

Masson trichrome

What specialization of the lateral cell membrane is predominantly found in the spinous layer of the epidermis?

1. There are no connections between the cells in this layer

2. GAP junctions and hemidesmosomes

3. Desmosomes

4. Occlusive junctions

Desmosomes

Which of the following is correct about connective tissue

1. Connective tissue is derived from the mesoderm

2. The connective tissue is composed mainly of epthelial and extracellular matrix

3. One of its functions is to secrete substances such as mucus, hormones

and/or enzymes

4. AIl are correct.

Connective tissue is derived from the mesoderm

What are intercalated discs

1. Essential organelles present in the muscle fibers for muscle contraction

2. Complexes of three types of cell junctions in cardiac muscle, including fascia

adherens, desmosomes and gap junctions

3. Special name given to the golgi in the cardiac muscle fibers

3. None of the above

Complexes of three types of cell junctions in cardiac muscle, including fascia

adherens, desmosomes and gap junctions

The lining epithelial tissue is characterized by:

1) Absence of polarization

2) Vascularization

3) Highly innervated

4) Little intercellular material

4) Little intercellular material

2. Pseudostratified epithelium is characterized by

1) All the cells are similar in shape

2) Absence of cilia

3) Has no basement membrane

4) May contain goblet cells

4) May contain goblet cells

Schwann cells are characterized by all EXCEPT:

1) They form myelin sheath

2) Present in peripheral nerves

3) Similar function to astrocytes

4) Separated by nodes of Ranvier2.

3) Similar function to astrocytes

Cells forming blood brain barrier are

1) Ependymal cells

2) Oligodendrocytes

3) Satellite cells

4) None of the above

4) None of the above

Elastic fibers can be detected

1) By Silver staining

2) By HE staining

3) PAS staining

4) None of the above

2) By HE staining

The characteristics of reticular fibers are

1) Type IV collagen

2) Can be detected by Verhoeff-van Gieson staining

3) Can be found in the kidney

4) Characterized by elasticity

3) Can be found in the kidney

Purkinje cells are

1) Present in the white matter of cerebrum

2) A cell layer in the white matter of cerebellum

3) Present in the grey matter of cerebellum

4) Present in cardiac tissue

3) Present in the grey matter of cerebellum

Fibrocartilage is

1) Type of cartilage present in trachea

2) Type of cartilage rich in fibroblasts

3) Present in meniscus

4) Cartilage with perichondrium

3) Present in meniscus

Connective tissue cells are all except

1) Osteocytes

2) Fibrocytes

3) Myocytes

4) Osteoclasts

3) Myocytes

Diads are

1) Present in smooth muscle cells

2) Composed of 2 T tubules

3) Present in skeletal myocytes

4) Composed of T tubule and sarcoplasmic reticulum cisterna

4) Composed of T tubule and sarcoplasmic reticulum cisterna

Adipose tissue is

1) Classified according to number of lipid vacuoles ( droplets)

2) One of the 4 basic tissue types

3) Characterized by large proportion of ECM to cells

4) Characterized by fusiform cells

1) Classified according to number of lipid vacuoles ( droplets)

Tendon is

1) Characterized by abundant collagen fibers

2) Dense connective tissue

3) Characterized by the presence of fibrocytes

4) All are correct

4) All are correct

Which is the TRUTH about Goblet cells

1) Are endocrine unicellular glands

2) Are present in the pseudostratified epithelium

3) Stain dark by HE

4) All are correct

2) Are present in the pseudostratified epithelium

Indicate the incorrect statement: Perichondrium

1) Is present in hyaline cartilage

2) Is present in elastic cartilage

3) Contains chondroblasts

4) Is not vascularized

4) Is not vascularized

Ganglia are

1) Accumulations of neuronal cell fibers outside the brain

2) Nerve ends present in visceral organs

3) Neuronal cell bodies outside the CNS

4) Are surrounded by adipose tissue

3) Neuronal cell bodies outside the CNS

Which cell type is present in the Haversian system lacunae

1) Chondrocytes

2) Osteocytes

3) Fibroblasts

4) Lacunocyte

2) Osteocytes

The ECM of connective tissue is not formed by

1) Glycoproteins

2) Surfactant sulfate

3) Reticular fibers

4) Proteoglycans

2) Surfactant sulfate

Nerve cell bodies contain

1) Sarcomeres

2) ECM

3) Nissl bodies

4) axons

3) Nissl bodies

The lumen of the blood vessels is lined by

1) Mesothelium

2) Stratified epithelium

3) Simple cuboidal epithelium

4) Endothelium

4) Endothelium

Mark the INCORRECT statement: Chondrocytes are

1) The cell type of fibrocartilage

2) Located in lacunae

3) Surrounded by vascularized matrix

4) Surrounded by ECM made of collagen and elastic fibers

3) Surrounded by vascularized matrix

The gray matter of the CNS

1) Is present in the center of the spinal cord

2) Is composed of neuronal processes

3) Contains satellite cells

4) Stains white die to the presence of myelin

1) Is present in the center of the spinal cord

Which of the following do NOT stain PAS+

1) Macrophages

2) Goblet cells

3) Fungi

4) Mucous exocrine glands

1) Macrophages