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What is metabolism
the total of an organisms chemical reaction
what is the difference between kinetic and potential energy
potential energy is based on spatial arrangement and position while kinetic is based on relative motion
which reaction increases entropy
exergonic
which reaction decreases entropy
endergonic
what are the characteristic of endergonic reactions
products have more energy than reactants
delta g is positive
free energy is absorbed (cold)
non spontaneous
anabolic
uphill reaction
stable to unstable
decreases entropy
what are the characteristic of exergonic reaction
reactants have more energy than products
downhill reaction
increases entropy
stable to unstable
spontaneous
delta g is negative
free energy released (hot)
catabolic
what is an example of an exergonic reaction
cellular respiration
what is an example of an endergonic reaction
photosynthesis
what is the role of ATP in metabolism
provides energy to do cellular work
what is the purpose of a catalyst
speeds up a chemical reaction without being consumed by it
what is the difference between competitive and noncompetitive inhibitors
competitive bonds at active site
noncompetitive bonds not at active site
what is the role of an allosteric activator
lock it in the active position
what is the role of an allosteric inhibitor
lock it in the inactive position
what are some factors that change the reaction of an enzyme and how are they changed?
temperature and pH and they are changed by Denaturation
what is the role of enzymes in biological systems
they speed up reactions by lowering the activation energy
what is the relationship between enzyme structure and enzyme specificity
the active site is specific to the substrate
active site
groove or pocket where substrate binds
substrate
the thing that binds to the active site
list 4 ways that enzymes can lower activation energy
1. template for reactions to come together
2. bends bonds to get in the transition state
3. good microenvironment (pH)
4. bonding or place for them to come together
how does substrate concentration affect the rate of an enzyme controlled reaction
more substrates equals more reactions
what happens to the rate of an enzyme controlled reaction when the substrate level is high and remains high? and why does that happen
The enzyme activity would level out because there is a limited number of enzymes and you can only bond a limited number of substrates to a limited number of enzymes
what environmental conditions affect enzyme activity
temperature and pH
Small nonprotein molecules needed for enzyme reactions
cofactor
organic cofactors; vitamins
coenzymes
chemicals that inhibit enzyme activity
inhibitor
enzyme inhibitors that resemble the substrate and compete with the substrate for the active site
competitive inhibitors
enzyme inhibitors that bind to the enzyme at a site other than the active site and cause the enzyme to change shape
noncompetitive inhibitors
enzymes with two conformations one active and one inactive
allosteric enzymes
what happens during feedback inhibition
the regulation of a metabolic pathway by its end product, which inhibits an enzyme at an earlier point in the pathway
catabolism
releases energy by breaking down complex molecules to simple molecules
anabolism
consumes energy to synthesize a complex molecule from simpler molecules
energy
The ability to do work or cause change
child at top of slide
PE
child sliding down slide
KE
water behind dam
PE
Water turning turbines
KE
Glucose
PE
Food molecules
PE
according to the first law of thermodynamics if the total energy before a reaction is 500kcal then the total energy after the reaction must be
500kcal
According to the second law of thermodynamics if the total energy before an energy exchange is 500kcal then the amount of useful energy after the exchange is
less than 500kcal
does the second law of thermodynamic contradict the first law
the second law does not contradict because the first law refers to a closed system while the 2nd law refers to an open system
do highly ordered living organisms violate the second law of thermodynamics
no because we consume and release energy
Organisms cannot use heat energy to drive their energy requiring processes does this mean that the heat released by metabolism is of no use to them
no because it helps us maintain homeostasis
what are the 3 main kinds of work performed by or in cells
mechanical chemical and transport
Explain how ATP performs cellular work
ATP is hydrolyzed a phosphate breaks off and energy is released
When ATP is produced, energy is required. What is the source of this energy?
glucose
When ATP is broken energy is released How is this energy used
to do cellular work and it is used in endergonic reactions to build molecules
What is the delta G of a system that is in equilibrium
there is none
Can a system at equilibrium do work?
no: because you have nothing to do work with if you are at equilibrium
of the light energy reaching the earth from the sun the earth's plants are believed to convert less than 1% into the form of potential energy stored in the chemical bonds of food molecules. What happens to the rest of the energy
gets released as heat (lost)