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Bowman's capsule
initial ultrafiltration of primary urine from blood plasma
Proximal convoluted tubule
reabsorption of most filtrate, some secretion
Loop of Henle
establishment of interstitial fluid osmotic gradient important for final urine formation in the collecting duct
Distal convoluted tubule
additional reabsorption and secretion
Collecting duct
final adjustment of urine composition
Nephron function equation
Amount filtered - Amount reabsorbed + Amount secreted = Amount of solute excreted
where is estrogen and testosterone secreted?
in the gonads
what does the hypothalamus do?
regulates body temperature, hunger, thirst, sleep-wake cycles, sexual behavior, and emotional responses
what is the pregnancy hormone?
human chorionic gonadotropin (hCG)
what does aerobic exercise do in phys?
skeletal muscles contract over a long period of time. ex: running
what does anaerobic exercise do in phys?
done briefly. ex: lifting, sprinting; over a short period of time
when does the bohr effect happen?
when exercising, making more co2 drop in affinity
Hypometabolism
low rate of metabolic activity, where body tissues or brain cells consume less energy (e.g., glucose) than normal
how is luteal phase triggered
by ovulation (specifically the surge in LH),
when does fertilization occur
it typically happens after the luteal phase has already begun
polycythemia
a disorder characterized by an abnormal increase in red blood cells (RBCs), leading to thicker blood, reduced flow, and heightened clotting risk
what happens in type 1 (long term exercise)
more mitochondria
lipid droplets
capillaries closer to fibers
easier for o2 to diffuse in
boosting CO
what happens in type II (short term exercise)
fibers should grow with more myofibrils, generating more force and glycogen
hyperglemia
high blood sugar thus high glut4 and glucose uptake
one being faster than the other is due
to vo2 max being high, larger lung ventricles
more mitochondria density
hypoxemia
low po2 of high altitude air. this will increase alveolar ventilation , less co2 and increase in blood pH
decrease muscle fiber diameter and shorter diffusion
suppresses metabolism and uses glucose for fuel
hypoxia
deprived of o2
increases gene expression and hematocrit
what is hypoxia caused from?
anemia - not enough rbc/hemorrhage
epas1 help manage this
eugenics
biological factors were primary drivers of human mental abilites
estimating gfr
sees how fast kidneys filter blood into urine
where are fluids distributed (in urinary system)
plasma, interstitial fluid, intracellular fluid
body fluid consists of
volume
osmolarity
conc. of solutes
pH
the urinary system regulates this
how does water get in our system
eating/drinking
amino acid made from biochem reactions
aerobic mech
how does water get in out system
exocrine gland (sweat)
urine excretion
breathing out (water out of lungs)
hyperosmotic -less dilute/more concentrate (less fluid)
u/p is greater than one
hypoosmotic -more dilute/less concentrated (more fluid)
u/p is less than one
nephrons
functional kidneys is responsible for urine formation ; thena lot of solute reabsobred and secreted
glomerular filtration
kidney's initial process of filtering waste, fluids, and electrolytes from the blood. excludes large plasma solutes, proteins but allows the rest to lumen of nephron
increase in blood pressure
increase in filtration
2nd major energy input to kindney and urine formation
active transport of na+ and na+/k+ pump
- favorable gradient solutes are reabsorbed early on
countercurrent multiplier
uses energy to create an osmotic gradient in the intersitual fluid
descending side of loop of henle
water reabsorbed by osmosis, passive transport
ascending side of loop of henle
more k+/na+, hyperosmotic
what hormones affect the kidney?
vasopressin and aldosterone
vasopressin
acts on cells on conducting duct -during the process of urine forming and reabsorbing h2o. increase plasma volume and blood pressure
osmolarity high
RAAS system (aldosterone)
in distal tubule and conducting duct- reabsorbing na+ (then more h2o reabsorbs)
increased vasopressin happens
if urine is concentrated
decreased vasopressin happens
if urine is dilute
what is renin
it is a enzyme in RAAS signaling which helps bring the low blood pressure back to normal
when body fluid is low (sweating or thirsty)
plasma osmolarity is high
organizational effects of hormones
during development, brain structure differs in sexes
activational effects of hormones
sex steroid levels, testosterone, estrogen, oxytocin
parthenogentic species
sexual ancestors only females that reproduce w/o fetilization
hermaphroditic species
can be male or female reproducing and producing both sperm and egg
also not always for reproduction
circulatory shunt
allows blood to bypass non func pulmonary circuit cuz the fetus has not developed that yet.