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Neuron
Highly specialized cells used to send signals throughout the nervous system
Dendrite
Short fibers that branch out from the cell body and pick up incoming messages
Cell Body
Made up of a nucleus, which contains a complete set of chromosomes and genes; cytoplasm, which keeps the cell alive; and a cell membrane, which keeps the cell enclosed
Axon
Single long fiber extending from the cell body; it carries outgoing messages
Myelin Sheath
White fatty covering on axons that increases the speed in which the message is sent and protects the nervous system
Demyelinating Disease
Multiple Sclerosis
Terminal Button (Synaptic Knob)
Structure at the end of an axon terminal branch
Synaptic Vesicles
Tiny sacs in a terminal button that release chemicals (neurotransmitters) into the synapse
The Synaptic Cleft
Tiny gap between the axon terminal of one neuron and the dendrites or cell body of the next neuron
Synapse
Area composed of the axon terminal of one neuron, the synaptic space and the dendrite of the next neuron
Neurotransmitters
Chemicals released by the synaptic vesicles that travel across the synaptic space and trigger adjacent neurons
Receptor Sites
A location on a neuron that receives incoming neurotransmitters that fits like a key into a lock
Reuptake
The neuron sending the message will take back any neurotransmitters left in the synaptic gap
Afferent (Sensory) Neurons
Carry the messages from the sense organs to the spinal cord or brain
Efferent (Motor) Neurons
Carry messages from the spinal cord or brain to the muscles and glands
Myasthenia gravis
An autoimmune disorder caused by an error in how nerve signals are sent to muscles. Acetylcholine is blocked, altered, or destroyed
Interneuron (Associative Neuron)
Neurons that carry messages from one neuron to another
The Reflex Arc
Resting Potential
Electrical charge across a neuron membrane- positive ions on the outside and negative ions on the inside. The neuron is doing nothing (resting)
Action Potential
The firing of a nerve cell; positives inside/ negatives outside
Graded Potential
A shift in the electrical charge in a tiny area of a neuron
Threshold of Excitation
The level an impulse must exceed to cause a neuron to fire
All or None Principle
Action potential in a neuron does not vary in strength; the neuron either fires at full strength or not at all
Absolute Refractory Period
A period after firing, when a neuron cannot fire again no matter how strong the incoming messages may be
Relative Refractory Period
A period after firing when a neuron is returning to its normal polarized state and will fire again only if the incoming messages is much stronger than usual
Acetylcholine
Motor (muscle) movement both involuntary/ voluntary; helps retain and organize memories; lack associated with Alzheimer's disease
Dopamine
Voluntary motor movement, alertness; acts as a reward system in the brain; increases when you are doing something that brings you pleasure; lack associated with Parkinson's Disease; excess associated with Schizophrenia
Serotonin
Mood control; lack associated with major depression disorder (MDD)
Norepinephrine
Alertness, arousal and reward; lack causes MDD
Endorphin
Released in response to stress or pain (natural opiate); can be increased by exercise, laughing, music; involved with addictions/ highs
GABA (Gamma-Aminobutyric Acid)
Regulates (slows) neural excitability; helps to control anxiety, and convulsions (seizures)
Glutamate
Excitatory neurotransmitter; important for learning and memory; higher levels when awake and in REM; too much can cause excitotoxicity: Excessive glutamate exposure damages neurons and leads to cell death
Substance P
Associated with the perception of pain (pain signaling), mood disorders, anxiety, vomiting
Psychopharmacology
Use of medications to treat mental health conditions
Agonist
Type of drug that mimics a neurotransmitter
Antagonist
Type of drug that blocks a neurotransmitter from entering the receptor sites
Reuptake Inhibitors
Certain drugs will block neurotransmitter reuptake, leaving more of the chemical in the synapse and allowing the receptors to continue to be stimulated
Neural Plasticity
The ability of the brain to change in response to experience or damage
Neurogenesis
The growth of new neurons
The Endocrine System
Consists of glands that secrete hormones into the bloodstream that help control bodily functioning
Pituitary Gland
The 'Master Gland' that produces the hormone that influences the secretion of the other glands
Growth Hormone
A hormone secreted by the pituitary gland
Posterior Pituitary
Releases oxytocin
Adrenaline
Produced by the adrenal gland, increased during the fight or flight response
Leptin
A hormone that acts on the brainstem and hypothalamus in order to maintain body weight and helps prevent hunger
Ghrelin
Known as the 'hunger hormone', relates to the stomach and hypothalamus, increases appetite and promotes fat storage
Melatonin
Hormone involved with falling asleep, connected to circadian rhythm and the 24/25 hour sleep cycle
Oxytocin
Related to female and male reproduction, involved in childbirth, increases when hugging, creates a feeling of love and trust
The Central Nervous System
Consists of the brain and the spinal cord, which together contain 90% of the body's neurons
The Brain
The main component of the central nervous system that controls the whole body
Spinal Cord
Complex cables of neurons that run down the spine, connecting the brain to most of the rest of the body
The Peripheral Nervous System
The way in which the rest of the body communicates with the central nervous system
The Somatic Nervous System
Made up of nerves that connect to voluntary skeletal muscles and sensory receptors
Autonomic Nervous System
Carries involuntary messages between the central nervous system and the internal organs
Sympathetic Nervous System
Prepares the body for quick action in emergencies, slows digestion, drains blood from the periphery of the body, releases hormones
Parasympathetic Nervous System
Calms and relaxes the body, slows heart rate, reduces blood pressure, promotes digestion
Hindbrain
Base of the brain mainly involved in life functions, contains Medulla, Pons, and Cerebellum
Medulla
Controls blood pressure, heart rate, and breathing
Pons
Controls facial expressions, connected to the limbic system, involved in sleep and alertness
Cerebellum
Controls certain reflexes, balance, fine motor movement, and forms of procedural learning
Midbrain
Region between the hindbrain and forebrain, important for hearing, sight, and can register pain
Forebrain
Largest region of the brain, with many important roles
Cerebral Cortex
The outer surface of the two cerebral hemispheres that regulates most complex behaviors
Frontal Lobe
Responsible for voluntary movement, attention, goal-directed behavior, and appropriate emotional responses
Parietal Lobe
Organizes information from throughout the body, contains somatosensory cortex
Occipital Lobe
Receives and interprets visual information
Temporal Lobe
Helps regulate hearing, linguistic processing, balance, equilibrium, and face recognition
Reticular Formation (RF)
Network of neurons in the hindbrain, the midbrain and part of the forebrain that filters sensory information that goes into forebrain to motivate you in a certain direction.
Thalamus
(Switchboard of the brain) relays and translates incoming messages from all of the senses other than smell.
Hypothalamus
Controls motivation and emotional responses, metabolic functions (body temperature, hunger, thirst), libido (sex drive), and the Endocrine System.
Corpus Callosum
A thick band of fibers connecting the left and right cerebral cortex.
Split brain
When the corpus callosum is cut (rarely done to ease severe cases of epilepsy) causing no connection between the left side and right side of the brain.
Limbic System
Ring of structures that play a role in learning and emotional behavior, made up of the thalamus, hypothalamus, amygdala, and hippocampus.
Hippocampus
Converts short-term to long-term memories; without this area people are unable to retain new information (Anterograde Amnesia).
Amygdala
Involved in emotions and aggression.
Hemispheric Specialization
The right and left side of the brain have different and specific functions.
Stronger Right Lobe
Associated with creativity, visual and spatial tasks, nonverbal imagery, face recognition, and more emotional responses.
Stronger Left Lobe
Associated with logic and language, operates more analytically, rationally, and sequentially.
Wernicke's Area
Located in back of the temporal lobe (left side), crucial in processing and understanding what others are saying.
Broca's Area
Found in the frontal lobe (left side), controls our ability to speak.
Aphasia
Damage to the parts of the brain that control communication, impacting the ability to speak or understand language.
Consciousness
Varying levels of awareness of thoughts, feelings, behaviors.
Circadian Rhythm
Sleep/Wake cycle, about 24 hours, can be changed by jet lag, shift work, or blindness.
Sleep
A state of consciousness in which we are aware of ourselves and our environment, but less aware than when you're awake.
Typical Sleep Needs for Infants
About 16 hours per day of sleep.
Typical Sleep Needs for Babies and Toddlers
From 6 months to 3 years: between 10 and 14 hours per day.
Typical Sleep Needs for Children (Ages 3 to 6)
Between 10 and 12 hours of sleep.
Typical Sleep Needs for Children (Ages 6 to 9)
About 10 hours of sleep.
Typical Sleep Needs for Children (Ages 9 to 12)
About 9 hours of sleep.
Typical Sleep Needs for Teenagers
About 9 hours of sleep per night.
Typical Sleep Needs for Adults
For most adults, 7 to 8 hours a night appears to be the best amount of sleep.
Typical Sleep Needs for Older Adults
Older adults are also thought to need 7-8 hours of sleep, but this sleep may be for shorter time spans and lighter.
Sleep Cycle
The normal pattern our body cycles through, about every 90 minutes, during uninterrupted sleep.
Stage 1 Sleep
Very light sleep; lasts about 10-15 minutes, with hypnagogic sensations and alpha waves.
Stage 2 Sleep
Light sleep; heart rate slows, body temperature decreases, sleep spindles and K complexes occur.
Delta Sleep (Stages 3 and 4)
Deep sleep; brain waves slow to long delta, hard to awaken, with stage 4 being the deepest sleep.
REM
Rapid Eye Movement
Paradoxical Sleep
Brain waves are active and look like you are awake, but the body is at its most relaxed.
REM rebound
If you are sleep deprived your body will go into long periods of REM to make up for the lost time.
Insomnia
Having difficulty falling and/or staying asleep for an extended period of time, leaving you tired all the time.