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Nervous System Def
The nervous system is a complex and highly organised network of specialised cells, formed from neurons and glia
function of the Autonomic NS
that is responsible for the involuntary and autonomous regulation of the body's visceral muscles, organs, and glands.
What is the primary function of the nervous system?
To enable the brain to receive information from both internal and external sources and respond accordingly.
What are the two main components of the nervous system?
Central Nervous System (CNS) and Peripheral Nervous System (PNS).
What does the Central Nervous System (CNS) consist of?
The brain and spinal cord.
What is the function of the CNS
1.
Coordinates incoming sensory info and initiates outgoing motor responses
2.
Unconscious and conscious responses/ voluntary and involuntary and reflexes
3.
Receives info from Peripheral NS, sends a response to Peripheral NS
Brain Def
The brain is an intricate network of cells that plays a vital role in processing information received through neural pathways from the body and in directing actions within the body
Function of the brain
Receives, Integrates and initiates a motor response
Regulates and guides all parts of NS
regulates vital body functions unconsciously -> breathing heart rate
responsible for higher order functions and origin of emotions, personality and humour
Communicates with body through spinal cord, nerves and cranial nerves
function of cranial nerves
Cranial nerves connect brain directly to organs and mucles
part of peripheral NS
Spinal Cord Def
A long, thin bundle of nerve fibres and tissues that extends from the base of the brain to the lower back and is encased by a series of bones called the vertebrae which extends further than the actual cord
Function of Spinal Cord
1.
Carry sensory information from body (PNS) to brain for processing
2.
Carry motor information from the brain to the body (PNS)
Exception for these two functions are during involuntary responses
Spinal reflex -> no input from brain
Where are sensory/motor info passed through
Afferent Tract (upwards) -> sensory
Efferent Tracts (downwards) -> motor
What happens when spinal cord is injured
If injured brain loses sensory input and control over the body
Higher up injuries in spinal cord are more severe -> greater no of nerve connections between brain and body disturbed
What is the role of neurons in the nervous system?
Neurons are responsible for communication within the nervous system.
What is the role of glia in the nervous system?
Glia support the functions of neurons.
What is in the Peripheral NS
Somatic System and Autonomic System and all neurons outside CNS
Peripheral NS Def
The peripheral nervous system is the complete network of neurons located outside the central nervous system that comprises of muscles, organs and glands
Peripheral NS function
Carries info to and from CNS
Afferent neurons (from sensory organs) -> CNS
Efferent neurons (from CNS) -> muscles
Somatic NS def
voluntary system that consists of both a voluntary sensory function and a voluntary motor function
Somatic NS function
Transmits sensory info (from receptor sites) -> CNS
- Info from CNS to the muscles that control movement
- Sends info to skeletal muscles (controls voluntary movement)
Autonomic NS def
Network of nerves that connects the CNS with the body's visceral muscles, organs and glands
What are the two branches of the Autonomic Nervous System?
Sympathetic Nervous System and Parasympathetic Nervous System.
What is biofeedback
a person receiving info about the state of an internal bodily activity that occurs automatically
How is biofeedback related to Autonomic NS
Autonomic NS doesn't need conscious effort to function
However conscious control can possibly be exerted over ANS (blinking)
This is done through a process called biofeedback
eg (learning techniques, monitoring devices)
What is the role of the Sympathetic Nervous System?
To prepare the body for vigorous activity or stressful situations by activating visceral muscles, organs, and glands.
- releases adrenaline from adrenal glands
- physiological function suppressed
- an arousing or activating system
Sympathetic NS def
Division of the NS that activates visceral muscles, organs and glands to prepare the body for vigorous activity or to deal with a stressful of threatening situation
What does the Parasympathetic Nervous System do?
Counterbalances sympathetic NS -> returns body to a state of calm once stress or threat is not present
Maintains homeostasis during periods of low stress (body's natural state of equilibrium)
Parasympathetic NS def
Division of the autonomic nervous system that keeps the body functioning effectively
What occurs when Sympathetic NS is active
Dilates pupil
Accelerates heartbeat
Inhibits digestion
Stimulates glucose release by liver
Stimulates secretion of epinephrine and norepinephrine
Relaxes bladder
Inhibits the erection of sex organs
What occurs when Parasympathetic NS is active
Contracts pupil
Slows heartbeat
Stimulates digestion
Stimulates gallbladder
Contracts bladder
Stimulates erection of sex organs
What happens if both the Parasympathetic and Sympathetic NS are active at the same time
If both are active -> one system dominates over the other
Usually, the parasympathetic system as it is involved in everyday functioning
Voluntary vs Involuntary Responses
Voluntary
Have control over -> involved in decision-making
eg. (Walking/speaking)
Involuntary
don't have conscious awareness
eg. (breathing/heart rate)
Conscious vs Unconscious responses
Conscious response
Voluntary, goal directed and requires a level of control
Controlled by somatic NS, involves CNS (spinal cord travel)
Unconscious response
Involuntary, unintentional, automatic
Regulated by Autonomic NS
Reflex Def
A reflex is a response to sensory stimuli that is unlearned and innate. These responses tend to be simple behaviours that contribute to our safety and survival
Spinal Reflex Def
An adaptive behaviour designed to keep us away from danger and harm. An automatic response initiated by interneurons in the spinal cord rather than the brain
- Unconscious, involuntary and automatically occurring response only to some stimuli (no brain involved)
Adaptive Behaviour Def
A behaviour that increases an organism's chances of survival
A response that helps maintain homeostasis (internal balance)
A behaviour that improves the ability to cope with the environment
A response that has survival value
Why is the spinal cord an adaptive behaviour
Produces an automatic rapid response
No conscious thought
Reduces injury/prevents harm
Process of a Spinal Reflex
1. Sensory stimulus detected by sensory receptors
2. Sensory neurons carry info via a sensory pathway to spinal cord (afferent)
3. Interneurons in spinal cord initiate an involuntary motor movement
4. Relayed to motor neurons and carried via a motor pathway to muscles (efferent)
5. Muscles perform reflex response without input from the brain
6. Sensory stimuli reach brain -> pain
Spinal Reflex benefits
1.
Pain can't be felt until messages reach brain even if motor response has occurred
Quicker response -> only if it enhances survival
- Thus, it is an adaptive response -> saves time in situations that can be dangerous -> increases survival
What does the Spinal Reflex demonstrate
The spinal reflex demonstrates that a response to a particular sensory stimulus can have both an unconscious and conscious component, one occurring before the other. For each reflex action, a handful of neurons simply convert a sensory stimulus into an action.
Neurons Def
is an individual nerve cell that is specialised to receive, process and/or transmit information to other cells in the body.
3 types of neurons
Motor Neuron receives messages from CNS -> sends to effector site
Sensory Neuron sends message towards CNS
Interneuron in the CNS
Parts of the Neuron
Axon
Dendrites
Myelin
Soma
Axon Terminals
Synapse
Axon function
single tubelike extension -> transmits neural info to other neurons
Dendrites function
detects and receives info from other neurons
Soma function
collects and integrates info before info is passed on
myelin function
white fatty substance of glial cells surrounds the axon
Insulates axon -> prevents interference from activity of other nearby axons
Axon terminal function
Stores and produces neurotransmitters into synaptic gap
Synapse definition
Space between two neurons in a neural pathway
What is the difference between communication within a neuron and communication between neurons?
Communication between neurons -> electrochemical process -> uses chemical energy
Communication within neuron -> electrical energy
Presynaptic neurons def
the neuron that release neurotransmitters from the axon terminals.
Post synaptic neurons def
the neuron that receives neurotransmitters through receptors on the dendrites.
Process of neurons firing
1.
Neural impulse reaches the axon terminals of the presynaptic neuron
2.
Causes vesicles to release neurotransmitters into the synaptic gap
3.
Neurotransmitters bind to receptor sites on the dendrites of the post synaptic neuron (lock and key process)
4.
Neurotransmitters than makes the
Post synaptic neuron more likely to fire (excitatory)
Post synaptic neuron less likely to fire (inhibitory)
Functions of a neurotransmitter
Excite neuron to fire
Inhibit neuron from firing
Neurotransmitter definition
Neurotransmitters are chemical messengers released by neurons to transmit signals to other neurons, muscles, or glands, enabling communication throughout the nervous system.
Excitatory neurotransmitter function
Increase likelihood of post synaptic neuron firing an action potential or neural impulse
Glutamate
Function of Glutumate
Essential for memory and learning
Enhances information transmission
Involved in perception thinking movement
How is Glutumate involved in learning
Stimulates structural and functional changes to connections between neurons
Glutamate is released when a neural pathway associated with an experience is activated or stimulated.
Inhibitory neuron function
decrease the likelihood that the post-synaptic neuron will fire an action potential or neural impulse
GABA function
Essential for motor control vision and decreasing anxiety
Maintains neurotransmission at an optimal level
Low levels associated with seizures anxiety and phobias
Without GABA too much postsynaptic neurons
Why does there have to be a balance of neurotransmitters in the brain
1.
need to be in balance
too much or too little of certain neurotransmitters -> harmful to the functioning of neurons.
2.
without sufficient levels of GABA -> activation of post-synaptic neurons may get out of control because the excitatory effects of glutamate take over, leading to mental disorders such as anxiety.
3.
imbalance often associated with hyperactivity in various regions of the brain and increased arousal because of sympathetic nervous system activation.
resulting in physiological responses such as increased heart and breathing rates.
4.
When brains neurochemistry is in balance, the inhibitory action of GABA counterbalances the excitatory activity of glutamate and vice versa
Neuromodulator def
Subclass of neurotransmitters -> chemical molecules that alter the overall effectiveness of neural transmission in entire regions of the brain
Through increasing/decreasing responsiveness of many neurons to neurotransmitter signals or action potentials
Physical change of neuromodulators
Increase in dendritic receptors in the post-synaptic neuron (improving post-synaptic stimulation).
Role of Neurotransmitters
To transmit chemical signals to the adjacent neuron
Site of release for Neurotransmitters
Into the synapse
Site of release for Neuromodulators
Outside the synapse into the neural tissue in brain regions
Target of Neurotransmitters
A single post-synaptic neuron
Target of Neuromodulators
Groups of neurons
Speed of action for Neurotransmitters
Moderately fast
Speed of action for Neuromodulators
Moderately slow and last for longer periods
Role of neuromodulator
To alter the neural transmission of neurons by controlling the synthesis and release of neurotransmitters
Dopamine def
a multifunctional neurotransmitter with both excitatory and inhibitory effects that is involved in many CNS functions in addition to pleasure, such as movement, attention, mood, cognition and motivation
Where does the dopamine reward system occur
produced in the ventral tegmental area and travels in neurons to the nucleus accumbens and then the prefrontal cortex
What is the dopamine reward system
The reward pathway refers to a group of structures in the brain that are activated by rewarding or reinforcing stimuli.
How does the dopamine reward system work
when we are exposed to rewarding stimuli, the brain increases the release of dopamine along this reward pathway, which modulates the brain activity of the structures along it.
How is dopamine involved in thirst and drinking
Reward signals are carried by dopamine along the brain's reward pathway -> plays a role in drinking behvaiours/thirst
The gulping motion made by the throat as liquid is swallowed sends a message to the brain that water has been consumed, quieting the neurons that generate the urge to drink.
thirsty mice had a large surge in dopamine levels after drinking water.
however, mice that had water injected directly into the stomach did not release any dopamine afterwards
Implies drinking water as rewarding
How is dopamine involved in addiction
Most addictions are caused by the brain's inability to produce dopamine naturally without the behaviour or the substance that someone is addicted to
What is the anticipation effect in terms of dopamine
Anticipation Effect: Dopamine release is increased during the moments leading up to a potential reward or win, referred to as an anticipation effect.
How is dopamine involved in gambling
Gambling: Losing money when gambling triggers the rewarding release of dopamine almost to the same degree that winning money does. This can set off an urge to keep playing rather than walk away, referred to as 'chasing losses'.
how is dopamine involved in Hunger and Eating
Hunger results from a decrease in the baseline dopamine levels in our brain -> trigger a series of reactions in the brain -> increasing dopamine-dependent behaviours such as seeking out food and eating it.
Cravings: If you have a craving for chocolate, when you eat it, your brain releases more dopamine than if you ate something you were not craving.
Serotonin definiton
Serotonin is an inhibitory neurotransmitter that also acts as a neuromodulator, influencing a variety of brain activities.
How is serotonin involved in the GBA
More than 90% of the body's serotonin is found in the gastrointestinal tract as a part of the gut-brain axis, where it has a role in regulating bowel function and in reducing appetite
Where is the serotonin pathway
Originates in the brainstem and extends to almost all areas of the cerebrum including the cerebral cortex.
How does damage impact the serotonin pathway
Impairments to the serotonin pathway system have been linked to anxiety disorders and depression, as well as Parkinson's disease.
Serotonin role in mood
Balanced serotonin levels often lead to calm, focused, happy and stable moods. When levels dip too low, this has devastating effects because low serotonin levels are most commonly associated with depression and anxiety.
Serotonin role in sleep
Imbalance in serotonin leads to restless sleep during which a person wakes up often, leading them to lack sleep at night and desire sleep during the day.
To sleep, you need to have high sleep pressure. Research generally shows that if the brain lacks serotonin, a person will have a reduced sleep pressure, thus increasing restlessness and wakefulness.
Serotonin role in impulsitivity
A lower level of serotonin in the brain, particularly in the cerebral cortex, leads people to discount a delayed reward, increasing impulsive behaviours.
Serotonin role in aggression
Low levels of serotonin weaken communication between the amygdala and the frontal region of the cerebral cortex, making it more difficult for the frontal area (which makes decisions) to control and regulate emotional responses to anger generated within the amygdala.
Synaptic Plasticity def
Ability for the brains neural structure to be changed by experience
basics for learning and memory
What is LTP
Long lasting strengthening of synaptic connections
Results in more enhanced and effective synaptic transmissions
- Easier activation of post synaptic neurons
Effect of LTP
improve ability of post and presynaptic neurons to communicate at the synapse
Post Synaptic neurons become more responsive as connection strengthens
The more we use information -> more LTP process strengthens pathway -> easier to remember
Advantages of LTP
Increases efficiency in transferring info along pathway
Decreases chance of forgetting learnt info
Structural Changes of LTP
Increase in dendrites - bushing
Increase in receptor sites
Increase in the number of vesicles
Functional Changes of LTP
Increase in neurotransmitters in vesicles
More neurotransmitters are secreted into the synaptic gap from the terminal buttons - shown through increased glutamate
What is LTD
Long lasting decrease in strength of synaptic transmission
Results from lack of stimulation of pre and post synaptic neurons
Post synaptic neuron becomes less responsive to neurotransmitter released by presynaptic neuron
Advantages of LTD
Weakening or elimination of unused synapses -> prunes unnecessary information/connections
If all synapses were strengthened -> new info couldn't be encoded due to limit being reached
Allows us to correct thinking or prior incorrect knowledge
Provides basis of blocking or erasing unwanted thoughts/feelings and behaviours
Structural changes in LTD
Pruning of synaptic connections
Functional changes in LTD
Decrease in neurotransmitter in vesicles
Less neurotransmitters secreted into the synaptic gap
Similarities between LTD and LTP
Both are long lasting and enduring
Both involve glutamate
Both occur at glutamate synapses
Both involve changes in excitability
Both are dependant on activity
Both are critical in learning
Both are observed in brain areas that revolve around learning and memory