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Jacob
________ and Monod coined the term operon to describe a set of coordinately regulated bacterial genes that are transcribed together into one polycistronic mRNA.
E coli
A protein known as the catabolite activator protein (CAP) has long been viewed as exerting positive control of many operons in ________, including the lαc operon.
lactose metabolism
The group of genes involved in ________ was termed the lαc operon.
allosteric regulation
In ________, a small molecule binds to a protein and causes it to change its shape and activity.
inducer
A(n) ________ is a small molecule that triggers transcription of a specific gene.
Positive control
________ occurs when a regulatory protein called an activator binds to DNA and triggers transcription.
Negative control
________ occurs when a regulatory protein called a repressor binds to DNA and shuts down transcription.
Transcriptional control
________: The cell could make mRNAs only for proteins it needs.
Negative feedback control
________ is a form of control in which the final product of a pathway inhibits the production of the product.
lαc operon
The repressor binds to a DNA sequence in the ________ called the operator.
Post translational control
________: After translation, many proteins have to be activated by chemical modification, such as the addition of a phosphate group, in order to function.
Transcriptional control
The cell could make mRNAs only for proteins it needs
Translational control
The cell could prevent the mRNAs for unneeded proteins from being translated
Post-translational control
After translation, many proteins have to be activated by chemical modification, such as the addition of a phosphate group, in order to function
Translational control
The cell could prevent the mRNAs for unneeded proteins from being translated.
Constitutive mutants
Cells that are abnormal because they produce a product at all times instead of regulating expression of the product are called
Operator
The repressor binds to a DNA sequence in the lαc operon called the
catabolite activator protein (CAP)
has long been viewed as exerting positive control of many operons in E. coli, including the lαc operon.
Co-repressor
The only difference is that for the trp operon the small molecule regulator is called a
Global gene regulation
is the coordinated regulation of many genes.
Regulon
is a set of separate genes and operons at contain the same regulatory sequences and are controlled by a single type of regulatory protein
