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Interaction of a pathogen-associated molecular pattern (PAMP) with a pattern recognition receptor (PRR) results in
transmembrane signal transduction that initiates transcription of genes involved in phagocytosis, inflammation, and pathogen killing.
Which of the following is an example of a barrier defense that forms part of the innate immunity of vertebrates?
Acidity in the stomach kills many microbes.
The process by which antibodies block interactions between pathogens or their products and host cells is termed
neutralization.
What does the plasma membrane of a phagocyte attach to on a microorganism?
Glycoproteins
The process by which a phagocyte moves toward a chemical signal at the site of an infection is called
chemotaxis.
Which of the following phagocytic processes occurs last in the sequence?
Exocytosis
What is the role of opsonins?
They create "handles" that make it easier for the pseudopods of phagocytes to attach to the microbe invader.
What is a phagolysosome?
The structure that results from the fusion of a phagosome and a lysosome.
Which of the following cell types is involved in innate immunity?
macrophages
Which of these immune system cells are phagocytes?
neutrophils
Some cells may not have class I MHC proteins on their surfaces due to a viral infection or because they have become cancerous. How does the immune system respond?
Natural Killer cells attach to these cells and kill them.
Which of the following is another term for antibodies?
immunoglobins
How are immune cells able to detect foreign pathogens?
They are able to detect structures on the surfaces of foreign cells that are not found in the host.
How does a capsule help certain bacteria evade detection by the immune system?
The capsule is composed of polysaccharides that are similar to those found in the host; thus, the immune system does not recognize it as foreign.
Which of the following microorganisms actually grows inside the macrophage?
Tuberculosis bacterium
How does the protozoan Trypanosoma evade detection by the immune system?
It can change the surface antigens frequently, preventing the immune system from tracking it.
Which statement about protective mechanisms employed by normal microbiota is false?
Normal microbiota spreading to locations where they are not normally found to prevent colonization from pathogens.
Arrange the following steps in order to describe the chronological order of the events in phagocytosis.
chemotaxis
adherence
ingestion
maturation
killing
elimination
Choose the statement that best describes why the lectin or alternative pathway would stimulate a more immediate response than the classical pathway.
Neither pathway relies on antibodies.
Choose the statement that is the most likely outcome of enhanced margination.
enhanced phagocytosis
The rapid increase in adaptive immunity after a second antigen exposure is called
immune memory.
Mucous membranes are a part of
innate defense.
According to the animation, B cells interact directly with
helper T cells.
Which of the following defense systems would be involved in fighting a viral pathogen?
T lymphocytes
According to the animation, antibodies interact with which innate defenses
Phagocytosis and the complement system
Which cells directly attack abnormal cells in the body?
Cytotoxic T cells
Chemokines are a group of small proteins that
attract T cells, phagocytes, and lymphocytes, as well as potentiate specific immune responses.
The cells active in both innate and adaptive immunity develop from common pluripotent precursors in the bone marrow called
stem cells.
Why is the spleen considered a secondary lymphoid organ?
B and T lymphocytes migrate to the spleen.