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Radiation can be emitted in the form of
particles, electromagnetic radiation, or both
Emitted radiation includes
alpha, beta, and gamma rays
Alpha particles are ___ charges
positively
Beta particles are ___ charges
negatively
Gamma rays have ____ charge
No
____________ occurs as the source emits radiation in attempt to become stable
Radioactive decay
Elements with higher atomic number are more likely to be
radioactive
____ is the radioactive sources rate of decay
Activity
The SI unit of activity is the
Becquerel (Bq)
1 Becquerel (Bq) = ___ dps
1 dps
1dps = ____ Curie(ci)
2.70X 10^ -11 CI
What is formula for activity?
A= Ao (0.5) ^ t/T1/2
__________ of a radioactive source describes the duration of time it takes for the activity to decay to half the original value
Half- Life (T 1/2)
______ of a radioactive source describes the average lifetime decay
Mean life (Ta)
Radioactive materials can be used for diagnostic tests like
nuclear medicine
What is example of nuclear medicine radioactive material
Technetium-99
What are some examples of therapeutic radioactive materials?
Iodine-125, Palladium- 103, iridium- 192, colbolt-60, Strontium- 90
_______ is a "short-distance therapy" that uses radioactive materials to treat certain cancers internally
Brachytherapy
Brachytherapy sources typically have lower energies that have a
rapid- fall off
Brachytherapy is common used for treatments of the
Uterus, cervix, lung, prostate, and breast
There are different types of brachytherapy applications that can be used depending on the
size and location of the tumor
__________ are plastic molds that conform to patients skin surface with source placed on the outer surface mold
External applicators
External applicators, brachy, are used to treat
tumor beds, skin surfaces, or mucosal surfaces
_____ is a brachy applicator with radioactive source placed within body cavity
intracavitary
Intracavitary applicators are use to treat
GYN tumors
Vaginal cylinders, tandem and ovoid, and fletcher-suit applicator are what type of brachytherapy appicators
Intracavitary
_____ is a type of brachy where the radioactive source is placed with needles, wire, or seeds directly into malignant tissues
interstitial
The most common radioisotopes used in brachytherapy are
sealed sources
What does sealed sources mean?
that they are covered by metal casing
sources that are used for low dose rate brachytherapy (LDR) treat
40-200 cgy/hr
Sources that are used for high dose rate brachytherapy (HDR) treat
12Gy/hr or .2 cgy/hr
_____ was the original radioactive isotope, which helped start brachytherap
Radium (ra-226)
Half life= 2.67 days
Ex use: liver caner and lymphoma treatment
Exampling which radioactive source:
Yttrium (y-90)
Half life= 2.7 days
Ex of use= Permanent implant (seeds) for prostate cancer treatment
Exampling which radioactive source:
Gold (Au-198
Half life= 8 days
Ex of use= thyroid cancer treatment
Exampling which radioactive source:
Iodine (I-131)
Half life= 17 days
Ex of use= permanent implants for prostate cancer treatment
Exampling which radioactive source:
Palladium (Pd- 103)
Half life= 50.5 days
Ex of use= treats pain caused by bone mets
Exampling which radioactive source:
Strontium (sr- 89)
Half life= 59.4 days
Ex of use= permanent implants for the treatment of prostate cancer
Exampling which radioactive source:
Iodine (I-125)
Half life= 73.8 Days
Ex of use= HDR treatments and made of nylon ribbons with seeds
Exampling which radioactive source:
Iridium (Ir-192)
Half life= 5.26 Years
Ex of use= External beam treatments
Exampling which radioactive source:
Cobalt (Co-60)
Half life= 28 years
Ex of use= treats cancers in the eye (pterygium)
Exampling which radioactive source:
Strontium ( Sr-90)
Half life= 30 years
Ex of use= Brachytherapy for cancers of the cervix or uterus
Exampling which radioactive source:
Cesium ( C-137)
Half life= 1,622 years
Ex of use= original radioactive isotope
Exampling which radioactive source:
Radium (Ra- 226)
_____ radiation is man-made radiation created within an x-ray tube that consists of a cathode and an anode within a class envelope
photon
Photons (x-rays) are formed when a high voltage is applied between the
cathode and anode
The voltage of proton is supplied by a
generator
1 kilovolt = ___ volts
1000
1 megavolt= ___ volts
1,000,000
1 megavolt= ____ kilovolts
1,000
_____ is a negatively charged electrode with a tungsten filament that releases electrons when heated ( aka thermionic emission)
Cathode
Tungsten has a Z number of ___ and melting point of ___
Z = 74
Melting point= 3370 Celsius
____ is a positively charged electrode made of tungsten and is also known as the target
anode
Rotating anodes allow for more ______
heat dissipation
Hooded anodes prevent unwated
secondary electrons
Targets in megavoltage therapy machines are known as
transmission targets
In a linear accelerator, there is a waveguide between the electron gun and target to increase
electron energies
Therapy x-ray photons have energies from
50 keV to 25 MeV
Common beam energies for linear accelerators range from
4MV to 25 MV
Orthovoltage energies range from
150-500 kV
Superficial therapy energies range from
50-150 Kv
When electrons interact with the target, they either produce
bremsstrahlung, x-rays or characteristic x-rays
______ is an electron interaction that occurs near the nucleus
Bremsstralung
In bremsstrahlung the electron does what?
Slows down as it approaches the nucleus and then changes uts direction
______ is where the incoming electron interacts with an inner shell electron, causing the inner shell electron to be ejected
Characteristic
With characteristic x-rays an outer shell fills the
new vacancy
Characteristic X-rays only occur in
Diagnostic Radiograph NOT radiation therapy
______ beam radiotherapy includes high-energy charged, particles, such as protons, alpha particles, and carbon ions
particle
What is a cyclotron?
Charged particle accelerator
What is a cyclotron used for
Used in proton herapy to speed up protons
The common benefit of protons is the dose distribution because of _____
bragg peak
Bragg peak is the dose curve of a proton beam. It starts off low at beginning but then rapidly rises toward the ends of the path and then.....
abruptly falls to zero
The depth of Bragg peak can be adjusted based on the
beam energy
X-ray photons are electromagnetic energy and travel in...
waves
Characteristic of a wave include
frequency, wavelength, velocity, and amplitude
___ is the number of waves that pass a given point in one second.
Frequency
___ is the measured distance between two specific points of the wave
wavelength
What an example of a wavelength?
Peak to peak or valley to valley
What unit is wavelength measured in?
meters
___ is how fast the wave is traveling (speed)
velocity
X-rays travel at the speed of
light in a vacuum
What is the SI unit for the speed of light?
3 X 10^8 m/sec
_____ us half the distance from one crest to one valley of the wave
Amplitude
____ have both wave and particle characteristics
photons
Photons have no
mass or charge and low LET
As the radiation beam travels through matter, it will diverge and decrease in intensity because of the
inverse square effect
The beam decreases in intensity because it is either absorbed or scatter in a different.......
direction than it travels through matter
The beam intensity will decrease more as the thickness of attenuating material _____
increases
3 multiple choice options
The radiation beam intensity (dose) with decrease with increasing distance due to the
beams divergence
____ is inversely proportional to square of distance from source
beam intensity
IF distance increases by two, then the intensity
decreases by 4
IF distance decreases by two, then intensity
increases by 4
PDD equations use the inverse sqaure law when implementing
Mayneord F factor
Beam quality describes the beams ability to
penetrate
Different types of radiation have different beam qualities and can produce different ____
amounts of response
Quality factor (QF) are assigned to describe the type of
Radiation
What is the quality factor of X-rays, gamma rays, beta particles, electrons
1
What is the quality factor of protons
2
What is the quality factor of neutrons
3 to 10
What is the quality factor of heavy particles (alpha particles)
20
___ interaction with electrons can produce coherent or elastic scattering, photoelectric effect and Compton scattering
Photons
3 multiple choice options