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substance use disorders
pathological use of a substance that leads to a disorder of use
symptom groups of substance use disorders
impaired control, social impairment ,risky use, physical affects (tolerance, withdrawl, intoxication)
addiction
chronic medial condition
intoxication
process of using substance to excess
tolerance
takes higher dose to achieve intial level of response
withdrawl
symptoms occur when a person stops using a substance
comorbidities with substance use disorders
psychiatric- any combo of two or more substance use disorders and mental disorders
risk factors for substance use disorders
genetics- runs in fams, twins
neurobiological- neutrotransmitters
environemntal- chronic stress, coping, social support, poverty (main)
theroy pf pvoerh
hard to get out
caffiene
most widely used psychoactive substance in world
result in intoxication, overdose, withdrawl
cannabis
third most common
hallucinogens
cause a profound disturbance in reality
acid, LSD, ketamines, PCP
inhalants
solvents for glues and adhesives, propellants, thinners, fuels
known for quick high via tolulating
inhalants- sudden sniffing death
rush, sudden cardioac respone with arrythmias and res sitress
opioid use disorder examples
heroin, prescription drugs
opioid intoxication
slow psychomotor, drowsy, poor memory, pin point pupils (myosis), consipation, dec in rr and bp, be aware of alcohol use
brady, hypotension, hypothermia, sedation, hypokinesis, slurred speech, head nod, euphoria, analgesia, calmness
opioid cravings result in
larger amounts of drug with longer periods of use, tolerance cycle
opioid intoxication may inflict (psych)
impairment in life roles, interpersonal conflict, and puts pt in psychically hazzardous situation
opioid overdose usually leads to? treatment? what does treatment do?
death usually due to res arrest, naloxone promotes breathing
opioid withdrawl
tachycardia, hypertn, hyperthermia, insomnia, mydriasis, diaphoresis, inc rr, tearing, rhinorrhea, muscle spams, abd cramps, n/v/d, bone/muscle pain, anxiety
opioid withdrawl drugs
methadone, clonidine, nuprenoprphine/naloxone, lofexidine
opioid maintenance
pharm- methadone or buprenorphine/naloxone reduce cravings, naltrexone prevents high
psychotherapy- Individual, behavioral, CBT, family
sedative, hypnotic, and antianxiety medication use disorder examples
benzodiazepines, benzo-like drugs, carbamates, barbiturates, barbiturate like drugs
treatment to overdose on sedative, hypnotic, and antianxiety medications
gastric lavage (stomach pump)
withdrawl treatment to sedative, hypnotic, and antianxiety medications
gradual reductoin to prevent seixures
stimulant use disorder examples
anphetamine type, cocaine
stimulant use disorder treatment of withdrawl
group/individual
diazepam for agitation
1-2 week cocaine withdrawl needs NO inpatient care, no drugs to reduce symp
depression treatment AFTER withdrawl is compete (buproprion)
stimulant intoxication
inc energy, decrease appetite, mental alertness, inc hr/bp, dilated pupils
long term= chest pains, panic attacks, depression, delsions/hallucinations
stimulant withdrawl
depression, hypersomnia, fatigue, irritability, poor concentration, psychomotor retardation, inc appetite, paranoia, drug cravings
tobacco withdrawl
distressing, treatment is behavioral therapy, hyponosis, nictoine replacement, buproprion, verniciline
gambling disorder treatment
gamblers anonymous, SSRIs, bupropion, mood stabilizers, anticonvulsants
alcohol use disorder- alcohol
sedatiive w initial euphoria
alcohol use disorder-scale of diagnosis
mild= 2-3 symp
mod=4-5 symp
severe=5 or more symptoms
epidemiology for alcohol use disorder
twice common in men, american indians/alaska natives highest rates
comorbiditiy for alcohol use disorder
bipolar, schizophrenia, antisocial, major depressive disorder
risk factors for alcohol use disorder
genetics- runs in fams
neurobiological- neurotransmitters affect judement
social- inc risk w peer pressure
cultrual- fam norms/values, parental control/guidance
heavy drinking
a lot of. drinking frequently
binge drinking
consuming a large amount of alcohol in a short period of time, typically defined as 5 or more drinks in 2 hours for men and 4 or more drinks for women.
alcohol intoxication- legal
blood concentration of 0.08-0.10 mg/dl
alcohol withdrawl
shakes/jitters 6-8 hrs
mild/mod= aggitation, low appetite, n/v, insomnia, low cognition, perceptual changes, inc bp, hr, temp
severe= seizures (12-24 hrs), delirium (within 72 hes)
ativan is replacement therapy
what is replacement therapy for alcohol use disorder
ativan to taper to zero
Wernicke-Korsakoff Syndrome
pt with heavy use of alcohol for many years may suffer from short-term memory disturbances
Wernicke’s encephalopathy
from alcohol use disorder
altered gait, vestibular dysfunction, confusion, and several ocular motility abnormalities
fetal alcohol syndrome
intellectual disability, low nasal bridge, epithancal folds, shortpalpebral fissure, thin upper lip flat midface
systemic affects of alcohol use disorder
peripheral neuropathy, alcoholic myopathy (cardiaomyopathy=poor heart pumping)
esophagitis, gastritis, pancreatitis, hepatitis, chirrosis
leukopenia, thrombocutopenia
cancer of head/neck
assessment of alcohol use disoder:
SBIRT= screening, brief intervention, and referral to treatment
AUDIT= alcohol use disorders identification test
CAGE 4= questions to identify alcohol abuse
CAGE-AID= same questions as CAGE but adds drug use to alcohol
codependence- alcohol use disorder
cluster of behaviors involving the families of alcoholic patients
overly responsible behaviors, define their self-worth in terms of caring for others to the exclusion of their own needs
alcohol use disorder implemntation
promote safety/sleep (FIRST LINE)
reintroduce god nutrition/hydration and self care
explore harmful thoughts and spiritual distress
health teaching/promotion of alcohol use disorder
prevention against genetic vulnerability
public classes
pharmacotherapy for substance use disorder
disulfiram, maltrexone, benzodiazepines
psychotherapy for sutbance use disoders
CBT and motivational interviewing
what is motivational interviewing
APRN driven, strengthen motivation for change