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Nucleic Acids
Repeating nucleotides (monomer) forms DNA (polymer)
Parts of a nucleotide
5 carbon deoxyribose sugar
Phosphate group ( - charge)
Nitrogenous base
The carbon sugar
5 carbon atoms which are shaped like a pentagon
1’ holds the nitrogen base
2” deoxyribose (H) or ribose sugar (OH)
3’ holds the hydroxide that bonds with the phosphate group of another nucleotide
5’ holds the phosphate group
Directionality of DNA
DNA runs antiparallel (opposite ends), with nucleotides added to the 3’ end of the growing strand.
DNA bonds
Hydrogen bonds between the nitrogenous bases (A-T is double bonded while G-C is triple bonded — makes it stronger) and phosphodiester bonds between the nucleotides.
Pyrimidines (T, C, with single rings) always bond with purines (A, G, with double rings) in nucleic acids.
RNA
differences to DNA:
ribose sugars
uracil
single stranded
similarities to DNA:
linear 5’ - 3’ strand
sugar-phosphate backbone
nucleotide monomers
nitrogen base = perpendicular to backbone