1/96
Flashcards covering key vocabulary and concepts from biology lectures, designed for exam preparation.
Name | Mastery | Learn | Test | Matching | Spaced |
---|
No study sessions yet.
Covalent Bonds
A bond between atoms where pairs of electrons are shared.
Polar Molecule
A molecule with an unequal distribution of electrical charge, having one end slightly positive and the other slightly negative.
Ionic Bonds
Bonds formed by the attraction between positive and negative charges.
Hydrogen Bonds
Weak intermolecular force- attraction between 2 water molecules.
Cohesion
The sticking together of water molecules due to hydrogen bonds.
Adhesion
Property of water, sticking to a solid surface.
Solution
A mixture of solvent and solutes.
Hydrophilic
Substances that dissolve in water; polar molecules.
Hydrophobic
Non-polar substances that do not dissolve in water, such as fats and lipids.
Metabolism
All the biochemical reactions that occur within an organism.
Buoyancy
The upward force that a fluid exerts on an object immersed in it.
Viscosity
The stickiness of a fluid that determines how easily it can flow.
Thermal Conductivity
Absorption and transfer of heat
Specific Heat
The amount of heat required to raise the temperature of a substance; water has a high heat capacity.
DNA
Deoxyribonucleic acid; used by living organisms to store hereditary information.
RNA
Ribonucleic acid; a polynucleotide chain.
Nucleic Acids
Polynucleotide chain of one or two types: DNA or RNA
Polynucleotide Chain
Long unbranched chain of nucleotides (DNA or RNA)
Genetic Code
Order of bases in DNA that determines the sequence of amino acids in a protein
Pentose Sugar
5 carbon monosaccharide sugar
Phosphate Group
Acidic and negatively charged
Purine
Nitrogenous base; Adenine (A) and Guanine(G)
Pyrimidine
Nitrogenous base; Cytosine (C) and Thymine (T)
Cell Membrane
Outer boundary of cells that encloses all its contents
Cytoplasm
Jelly like substance where all the organelles are suspended
Prokaryotes
Does not have a nucleus- just a strand/ loop of DNA floating around in the nucleoid.
Peptidoglycan
Cell wall is made of this
Eukaryotes
Plants, animals, fungi, etc all are
Plastids
A family of organelles with 2 outer membranes and internal membrane sacs
Vacuole
Flexible fluid filled compartment surrounded by a single membrane
Centrioles
Cylindrical objects that organise the assembly of structures composed of microtubules
Undulipodia
Cilia and flagella used to generate movement of the cell
Homeostasis
The maintenance of a constant internal environment
Essential amino acids
Cannot be synthesized in sufficient amounts so must be obtained from diet
Non-essential amino acid
Can be synthesized as are found in the body
Denaturation
Change to the conformation of a protein is called denaturation, which is permanent
Phospholipid Bilayer
Bilayer of phospholipids and other amphipathic molecules that form a continuous sheet- controls passage of substances and is maximum 10 nm
Phospholipids
Polar head consisting of glycerol and phosphate molecules and 2 nonpolar tails made of fatty acid chains
Amphipathic
Hydrophilic heads + hydrophobic tails
Integral Proteins
Hydrophobic on at least one part of their surface and therefore are embedded in the hydrocarbon chains- extend across the membrane
Peripheral Proteins
Hydrophilic on the surface and so not fully embedded in the the bilayer
Glycolipids
One of the phospholipids attached to a single monosaccharide carbohydrate chain- usually facing out of the cell
Glycoprotein
Protein embedded in the membrane attached to a single carbohydrate chain
Simple Diffusion
Net movement of substances from a region of high concentration to low concentration (down the concentration gradient) to reach equilibrium.
Facilitated Diffusion
Net movement of large polar molecules and ions down the concentration gradient till the point of equilibrium, without ATP
Channel Proteins
Integral Lipoproteins that contain a hydrophilic pore for ions to cross through
Carrier Proteins
Integral glycoproteins that bind to a solute and undergo conformational change to translocate solutes across the membrane
Osmosis
Net movement of water molecules down the concentration gradient to the point of equilibrium
Tonicity
Is the way cell membranes react to different osmotic conditions
Organelles
Discrete structures in cells that are adapted to perform one or more vital functions
Compartmentalization
Mechanism of creating compartments inside the cell
Expression of Gene
Use of gene in a cell (switches on)
Cell Differentiation
Expression of certain genes in different cell types
Stem Cell Niche
Precise location of these stem cells, provides an environment for them to remain inactive and proliferate for a long time
Totipotent Cells
Found in early stages of embryonic development and can differentiate into any cell type
Pluripotent Cells
Embryonic stem cells; totipotent→ pluripotent; can differentiate into a variety of cell types but not all
Multipotent Cells
Can differentiate into a limited number of cells with a specific tissue and is found in adults
Enzymes
Mainly proteins that function as biological catalysts
Catalysts
Substances that increase the rate of chemical reactions but are not changed by the reactions themselves.
Metabolism
Complex network of independent and interacting chemical reactions that occur in living organisms
Anabolic Reactions
Anabolic reactions build up smaller molecules into larger ones and require energy to do so
Catabolic Reactions
Catabolic reactions break down larger molecules into smaller ones and release energy
Active Site
Specific region of enzymes where substrates bind
Induced Fit
Molecular motion: Allows substrates to move closer to the active site by the chemical properties of the enzyme
Immobilized Enzymes
Enzymes attached to an insoluble material, enabling recovery, reuse and increased enzyme stability
DNA Replication
Production of new strands of DNA with base sequences identical to existing ones
Helicase
Ring shaped protein that separates the two strands of DNA by cleaving the hydrogen bonds
DNA Polymerase
Assembles new strands of DNA using the two original strands as a template
Transcription
Synthesis of RNA, using DNA as a template
Translation
The process of polypeptide synthesis using mRNA
mRNA
Messenger RNA that has a site to which the ribosome can bind
tRNA
Transfer RNA that translates the mRNA base sequence into the amino acids
Codons
Three bases coding for amino acids. Required triplets as only 2 bases aren't enough.
Gene Mutation
Change to the base sequence of the gene
Substitution mutation
One base in the coding sequence of a gene is replaced by another.
Insertion mutation
One extra nucleotide is added resulting in an extra base in the sequence of the gene
Deletion mutation
One nucleotide is removed resulting in one less base sequence of the gene
Non-sense mutation
Change of a codon into a stop codon
Missense mutation
Alteration of one amino acid in the sequence of amino acids. If it is positioned at an uncritical point, it does not have an effect, otherwise it can be lethal.
Parent cells
Cells that divide to form daughter cells by mitosis or meiosis
Daughter cells
Cells produced when a cell divides by mitosis and meiosis
Mitosis
Nuclear division resulting in 2 genetically identical daughter cells
Meiosis
Nuclear division consisting of two parts in order to result in 4 haploid daughter cells
Sister Chromatids
2 Chromatids that make up the double structure of the chromosome
Euchromatin
Active genes are loosely packed to make them easily accessible
Heterochromatin
Inactive genes tightly packed for better economy of space
Nondisjunction
Failure of homologous chromosomes or sister chromatids to separate properly during cell division
Alleles
Different versions of the same gene
Genotypes
The combination of alleles
Phenotype
The physical appearance/ characteristics expressed by the organism by the alleles
Dominant allele
Allele that is usually expressed and masks the expression of the other allele
Recessive allele
Allele which does not have an effect on the phenotype if the dominant allele is present
Phenotypic Plasticity
Organisms can respond to their environment by varying their patterns of gene expression.
Single nucleotide Polymorphisms
SNPs: Position in a gene where different bases can be present
Karyogram
Arrangement of chromosomes in order of size
Sex Chromosomes
X and Y chromosomes
Sex Linkage
A special case of linkage occurring when the affected gene is located on the sex chromosome (Usually X)