Bio exam 2 p2

studied byStudied by 0 people
0.0(0)
learn
LearnA personalized and smart learning plan
exam
Practice TestTake a test on your terms and definitions
spaced repetition
Spaced RepetitionScientifically backed study method
heart puzzle
Matching GameHow quick can you match all your cards?
flashcards
FlashcardsStudy terms and definitions

1 / 49

encourage image

There's no tags or description

Looks like no one added any tags here yet for you.

50 Terms

1
Which of the following is a term used to describe the collection of microorganisms that live in and on the human body?
Microbiome
New cards
2
Which of the following allows for a single gene to encode for more than one polypeptide?
alternative mRNA splicing.
New cards
3
Why are so many emerging infectious diseases linked to RNA viruses?
They lack the DNA proofreading mechanisms.
New cards
4
Which of the following is NOT a possible cause of epigenetic changes?
DNA mutations
New cards
5
In eukaryotes, DNA packing seems to affect gene expression primarily by
controlling access to DNA.
New cards
6
How does the Earth BioGenome Project differ from other large-scale genomics projects?
It aims to sequence the genomes of all organisms on Earth, not just a select few.
New cards
7
What are single nucleotide polymorphisms (SNPs)?
Variations in the DNA sequence that occur when a one base pair is changed
New cards
8
During which stage of meiosis does crossing over and formation of tetrads occur?
prophase
New cards
9
Technological advances to manipulate gene expression include which one of the following.
RNA interference gene silencing (RNAi)
New cards
10
After fertilization of an egg, the resulting zygote has
a diploid chromosome number - one from each parent
New cards
11
What type of RNA is considered coding RNA?
mRNA
New cards
12
In eukaryotes, DNA replication occurs in
5' -> 3' direction
New cards
13
What is correct order of stages of Mitosis?
Prophase, Metaphase, Anaphase, Telophase, Cytokinesis
New cards
14
Epigenetics refers to
A change in gene expression without a change in DNA base sequence.
New cards
15
Genetic changes that underlie oncogenesis alter fundamental properties of cells including all ofthe following except one choice. Which one is FALSE?
Malignant cells are more highly oxygenated and do not migrate toward a blood supply.
New cards
16
Infectious diseases that can be specifically transmitted from other vertebrate animals to humans are called
zoonotic diseases.
New cards
17
The 3-D structure of RNA is very different from DNA because
All of these choices are true.
New cards
18
Which of the following is a type of immunotherapy that involves modifying T-cells to target cancer cells?
CAR-T therapy
New cards
19
What is EGFR?
A gene that is associated with the development of cancer
New cards
20
Identify the following image.
https://lms.rpi.edu/bbcswebdav/pid-581961-dt-content-rid-9949945_1/xid-9949945_1
karyotype
New cards
21
Autosomal disorders cannot be caused by
X-linked disorders
New cards
22
What is epigenomics?
The study of how environmental factors can affect gene expression
New cards
23
Which of the following is a key component of the Sanger sequencing method?
DNA polymerase
New cards
24
What is the likelihood that a child of an affected parent with an autosomal dominant disorder will inherit the disorder?
50%
New cards
25
Which of the following genes are known to increase the risk of breast and ovarian cancer when mutated?
BRCA1 and BRCA2 genes
New cards
26
The Central Dogma in molecular biology refers to
DNA is transcribed into RNA and RNA is translated to protein.
New cards
27
What is the process by which new blood vessels are formed from existing blood vessels called?
Angiogenesis
New cards
28
The ENCODE Project revealed new insights about the human genome. Identify the one correctanswer.
Recognition that evolutionary change occurs through sequences that alter gene regulation.
New cards
29
Epidemiology is the study of the origin of diseases, how they spread, and how to prevent their spread. Why was Covid-19 considered a pandemic, yet the H5N1 bird flu was not?
A disease is named a pandemic when new incidences of the disease increase, spread rapidly, and with a very wide global distribution.
New cards
30
There is the need for differential gene expression in humans because of one of the following. Identify the one CORRECT answer.
Almost all cells contain the same genotype.
New cards
31
If the sequence of the DNA template strand for mRNA synthesis is ACC AAA CCG, the mRNA sequence is
UGG UUU GGC
New cards
32
X-linked conditions are more common in men than in women because
men need to inherit only one copy of the recessive allele for the condition to be fully expressed.
New cards
33
What is personalized medicine?
A type of medicine that uses genetic information to tailor treatments to individual patients
New cards
34
What is the purpose of adding dideoxynucleotides (ddNTPs) to the Sanger sequencing reaction?
To terminate DNA chain extension at specific bases
New cards
35
During anaphase,
sister chromatids separate into individual chromosomes and are pulled apart.
New cards
36
BRCA1 and BRCA2 are genes that are
essential for repairing damaged DNA.
New cards
37
Technological advances to manipulate gene expression include which one of the following?
CRISPR-Cas9
New cards
38
What is chromosome nondisjunction?
Failure of a chromosome to separate during cell division
New cards
39
What are some conditions that can result from chromosome nondisjunction?
All of the above
New cards
40
What does the ENCODE project aim to do?
Map all functional elements in the human genome
New cards
41
How does CRISPR work?
By cutting DNA at specific locations and allowing for precise editing of the genetic sequence
New cards
42
During DNA replication, one DNA strand is copied to make a new DNA molecule composed of two DNA strands. This new DNA contains
one strand is the original DNA strand and the other the new DNA strand.
New cards
43
We have learned the following from Cancer Genomics Project except for the following one statement that is FALSE.
All breast cancer patients have the same oncogenic signature.
New cards
44
A codon is
a triplet-nucleotide sequence that codes for a specific amino acid or termination of translation.
New cards
45
The following figure shows the lac operon in its active and inactive state. What molecule activates the lac operon to produce the 3 enzymes for lactose utilization?
lactose
New cards
46
What is CRISPR/Cas9?
All these choices are correct.
New cards
47
Transcription factors bind to
DNA
New cards
48
What is the likelihood that a child of two carriers of an autosomal recessive disorder will inherit the disorder?
25%
New cards
49
These small, single-stranded RNA molecules, 22 nucleotides long, can block the translation of mRNA and are involved in the expression of ~1/3 of all human genes. Choose the CORRECT answer.
microRNAs (miRNAs)
New cards
50
What is MRSA?
A bacteria that is resistant to certain antibiotics
New cards
robot