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Chemical buffer systems, respiratory center control, kidneys and liver
Three primary systems that regulate pH balance
Chemical buffer systems, respiratory center control
Two first lines of defense against fluctuations in systemic pH
Chemical buffer systems
Does not remove excess acid or base; just neutralizes the H+ or OH- ions
Respiratory center control
Increased alveolar ventilation removes CO2 and therefore decreases H2CO3/H+ and other volatile acids
Hypoxemia
Low PaO2
Hypoxia
Reduction of oxygen supply to tissues below physiological levels