Virology chapter 2

How is WNV spread?

It is spread by mosquitos

Where did WNV start?

Uganda

What are some characteristics of WNV?

50 nm

RNA code

Encodes polyproteins

What is odd about WNV symptomology?

only 1 in 5 develope any symptoms at all (flu stuff)

What is the cause of serious symptoms from WNV?

Chronic issues like ccancer, kidney, or other diseases can cause neurological issues in select people. 1-10 why develop central nervous issues die.

How is WNV detected

ELISA(enzyme linked immonosorbent assay) or molecular pcr

How do you deal with WNV?

Control mosquito population (no vaccine)

What mammals are resistent to WNV?

Rats, guinne pigs, and rabits

What are some characteristics of NIV (nipha virus)

40-600 nm

Single stranded negative-sense RNA

Where was NIV first found?

Malyasia

What are the symptoms of NIV?

Fever, headache, and potentially comas in 24-48 hours

What is odd about NIV

It can have a latent effect are reappear years later

How is it diagnosed?

ELISA or molecular pcr

What mainly transmits NIV?

Pigs

What are some characteristcs of rabies?

Bullet shaped virion

• Approximately 180nm long and

75nm wide

• Non-segmented, negative strand

RNA

How do you get rabies?

Bodily fluid from an infected individual gets into your system

How do you treat NIV?

All you can do is symptomatic care (no vaccine)

How is rabies diagnosed?

PCR and spinal fluid test but commonly require a host head

Why is elisa less useful for detecting NIV?

It requires a very high concentration of virus

How do we reduce rabbies?

Vaccinate pets and reduce exposure to infected animals.