Human Diseases SBA Question Bank

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100 Terms

1
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Which of the following signs may be a manifestation of primary biliary

cirrhosis?

Gynaecomastia

3 multiple choice options

2
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A patient with poorly controlled epilepsy has just started a new mediation,

they are unsure of the name. They have an appointment next week to have

their full blood count checked. What medication are the most likely taking?

Carbamazepine

3 multiple choice options

3
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A 78-year-old patient has poor eyesight and is waiting for surgery to improve

this. What is the most likely cause?

Cataract

3 multiple choice options

4
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Which white patch on the oral mucosa can often be managed effectively

with topical beclometasone?

Lichen Planus

3 multiple choice options

5
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A patient with multiple myeloma takes intravenous zoledronic acid. Which

of the following medications would increase their risk of osteonecrosis of

the jaw?

Prednisolone

3 multiple choice options

6
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An epileptic patient has extensive gingival overgrowth. Which medication is

the most likely to cause this in this patient?

Phenytoin

3 multiple choice options

7
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An 83-year-old edentulous patient with osteoporosis attends and Emergency

Department (ED) with a fractured mandible. The radiograph shows extensive

alveolar resorption with a displaced fracture extending through the left

body of the mandible. What is the most likely classification of this fracture?

Pathological

3 multiple choice options

8
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In a patient with bone or joint problems, what is the most likely diagnosis in

a patient with Bouchard's nodes?

Osteoarthritis

3 multiple choice options

9
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A patient with poorly controlled type 1 diabetes is what American Society of

Anaesthesiologists (ASA) classification?

III

3 multiple choice options

10
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Which part of the ear is affected in a patient who suffers from vertigo?

Labyrinth

3 multiple choice options

11
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An elderly patient slips outside your dental practice. They hit their head but

did not lose consciousness. A week later she reattends and seems confused.

What type of brain injury is she most likely to have sustained?

Subdural Haematoma

3 multiple choice options

12
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Which of the following drugs is a histamine H2-receptor antagonist?

Ranitidine

3 multiple choice options

13
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A patient who reports hallucinations and difficulty sleeping, which has

improved with haloperidol, is most likely to suffer from which condition?

Paranoia

3 multiple choice options

14
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A patient attends with a head injury. They are complaining of a headache

are irritable and cannot remember the incident. What is the most likely

diagnosis?

Concussion

3 multiple choice options

15
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A 14-year-old has inherited a genetic disorder from their father where they

have multiple supernumery teeth. Which conditions is this most likely to be?

Cleidocranial Dysotosis

3 multiple choice options

16
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Which neurotransmitter is most commonly targeted by medications used to

control Parkinson's disease?

Dopamine

3 multiple choice options

17
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A 5-year-old patient attends an Emergency Department (ED) with a

fractured distal radius. The radiograph shows an incomplete fracture of the

bone with no displacement. What classification of fracture is this?

Green Stick

3 multiple choice options

18
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A patient with epilepsy has been having a seizure in the dental chair for 5

minutes. How would you manage this patient?

5mg Buccal Midazolam

3 multiple choice options

19
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Following a blow to the face, a patient has a derange occlusion, a tear in

the gingival mucosa and a step can be felt on the lower border of the

mandible. What type of fracture is this?

Open, Displaced

3 multiple choice options

20
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What is the most likely type of shock to occur following a severe myocardial infarction?

Cardiogenic

3 multiple choice options

21
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A patient has a 3-month history of pain following extraction of lower left

third molar (LL8). They had radiotherapy 7 years ago to manageoropharyngeal carcinoma. On examination there is gingival erythema and exposed bone in the extraction socket. Which pathological process is most likely to have led to this patient's current position?

Endarteritis Obliterans

3 multiple choice options

22
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A patient with Barrett's oesophagus with oesophageal webbing is likely

demonstrating what type of altered cell differentiation?

Metaplastic

3 multiple choice options

23
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Which is the most appropriate blood test that may be used to investigate a

79-year-old female patient, complaining of headaches, tenderness on

palpation of her right temple and decreased vision in her right eye?

C-reactive protein (CRP) levels

3 multiple choice options

24
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The following drugs are used in the treatment of rheumatic disorders. From

the list below, which drug often needs to be avoided in patients with

asthma?

Ibuprofen

3 multiple choice options

25
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Calcium carbonate can be prescribed as part of the management of gastric

ulceration. What is its principal mechanism of action?

Neutralise Gastric acid secretion

3 multiple choice options

26
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23-year-old patient presents complaining of facial pain. On examination

they have pain when palpating the masseters bilaterally, there are no

palpable or audible joint noises. What is the most likely temporomandibular

disorder diagnosis?

myofacial pain

3 multiple choice options

27
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A 56-year-old patient complains of a localised constant dull ache in the

upper right first molar (UR6) region. This tooth was extracted 6 months ago.There are no precipitating or relieving factors. Clinical and radiographic

examination exclude pathology. What is the most likely diagnosis?

Persistent dento-alveolar pain

3 multiple choice options

28
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A patient attends your practice with a scabbed and ulcerated lesion on the

lateral aspect of their nose. It is quickly increasing in size and on

examination there are palpable ipsilateral cervical lymph nodes. What

would be the most appropriate management?

Refer to Oral maxillo facial surgery via 2-week wait pathway

3 multiple choice options

29
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Two minutes after chlorhexidine mouthwash rinse, your patient starts to

complain of difficulty breathing and develops a wheeze. On examination you

note a rash developing at the upper part of their chest and their lips

starting to swell. What is the most appropriate medication to administer?

Adrenaline

3 multiple choice options

30
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The part of the ear that is responsible for equalizing atmospheric pressure is

most likely to be the...

Eustachian tubes

3 multiple choice options

31
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When assessing a trauma patient, what would be the most appropriate

technique to open their airway?

Jaw thrust

3 multiple choice options

32
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Damage to cranial nerve V can lead to which of the following?

Anaesthesia

3 multiple choice options

33
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Damage to cranial nerve III can lead to which of the following?

Ptosis

3 multiple choice options

34
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A patient who had gallstones is most likely to have had which type of

surgery?

Cholecystectomy

3 multiple choice options

35
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A 28-year-old patient reports a history of oral ulcers. On further questioning

they divulge that they have also been to their GP for genital ulceration and

their optician as they have had sore eyes. What diagnosis might you be

suspicious of?

Bechet's disease

3 multiple choice options

36
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A patient presents with an indurated, rolled-edged ulcer to the tongue that

has been present for 1 month. What is the most appropriate initial

investigation?

incisional biopsy

3 multiple choice options

37
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Your patient has lost consciousness in the dental chair and cannot maintain

their own airway. What airway adjunct would be most appropriate to use

with this?

Guedel airway

3 multiple choice options

38
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Damage to the V cranial nerve could be assessed with which equipment?

Von frey hairs

3 multiple choice options

39
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Which of the following cancers is often associated with human papilloma virus infection?

oropharyngeal cancer

3 multiple choice options

40
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patient with a longstanding history of severe Crohn's disease is most likely

to have had which of the following surgery for symptom control?

Bowel resection

3 multiple choice options

41
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Orthopneoa is a possible symptom of?

Left sided heart failure

3 multiple choice options

42
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Which of the following are not likely causes of confusion in patients?

Prescription of a non-steroidal anti-inflammatory drug

3 multiple choice options

43
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Koilonychia (spoon shaped fingernails) is a sign of?

Chronic iron deficiency anaemia

3 multiple choice options

44
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A facially viable sign of hypercholesterolaemia is?

Xanthelasma

3 multiple choice options

45
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Which of the following signs is not a potential feature of rheumatoid arthritis?

Dupuytren's contracture

3 multiple choice options

46
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The stated alcohol consumption limit for females per week is?

14 units

3 multiple choice options

47
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Which of the following is not a recognised cause of finger clubbing?

Myocardial infarction

3 multiple choice options

48
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The artery used to take the pulse at the wrist in a patient is the?

Radial artery

3 multiple choice options

49
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Tachycardia is defined as?

Pulse rate >100 beats per minute

3 multiple choice options

50
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Bradycardia is defined as?

A pulse rate less than 60 beats per minute

3 multiple choice options

51
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At post-mortem examination a patient who died of myocardial infarction would show evidence of?

Coagulative necrosis

3 multiple choice options

52
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The skin has the potential to regenerate because?

The majority of cells are liable

3 multiple choice options

53
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At post-mortem examination a patient who died of cerebral infarction would show evidence of?

colliquative necrosis

3 multiple choice options

54
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Granulation tissue contains?

Fibrovascular tissue

3 multiple choice options

55
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Granulomas contain?

Macrophages

3 multiple choice options

56
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H1 receptors antagonists are prescribed to patients with?

Hay Fever

3 multiple choice options

57
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Which of the following viruses is the causative agent in cases of herpangina?

Enterovirus

3 multiple choice options

58
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Which diagnostic test is indicated if laboratory confirmation of herpes labialis is required?

Lesion swab for HSV PCR

59
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What is the risk of HBV transmission through a needlestick injury?

30%

3 multiple choice options

60
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Which of the following is the commonest route of HCV transmission in the UK?

Intravenous drug use

3 multiple choice options

61
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What is the mechanism of action of acyclovir?

Inhibition of viral polymerase enzyme

3 multiple choice options

62
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The most common AIDS opportunistic infection in the UK is?

Pneumocystis Jiroveci (Pneumonia)

3 multiple choice options

63
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The most common form of oral candidiasis in HIV-infected patients is?

Pseudomembranous Candidasis

3 multiple choice options

64
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The following is true regrind oral hairy leukoplakia?

Associated with Epstein - Barr infection

3 multiple choice options

65
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The Following are indicator diseases for HIV?

Oral Candidiasis

3 multiple choice options

66
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The following Is true of HIV?

Late diagnosis is associated with high morbidity and mortality

3 multiple choice options

67
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Which of the following is not a part of the innate immune system?

CD8+ T-cells

3 multiple choice options

68
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Which of the following is a true statement about the actions of the complement system?

Attracts phagocytic cells to the site of infection

3 multiple choice options

69
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Which of the following is a possible cause of primary infection?

Chronic mucocutaneous Candidiasis

3 multiple choice options

70
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Which of these is not a method of testing for allergic disease?

IgG4

3 multiple choice options

71
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Which of the following statements is true when using skin prick testing diagnosis of type 1 allergies?

Better sensitivity compared with specific IgE testing

3 multiple choice options

72
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Which of the following is not a risk factor for the development of latex allergy?

Pencillin Allergy

3 multiple choice options

73
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In anaphylaxis, the correct of adrenaline to be administered intramuscularly is?

0.5ml 1:1000

3 multiple choice options

74
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What is the mechanism of action of methotrexate?

Competitive inhibitor of dihydrofolate reductase

3 multiple choice options

75
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Behcets syndrome is not associated with?

Vitamin B12 deficiency

3 multiple choice options

76
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Which of the following is defined as an organ-specific autoimmune disease?

Autoimmune thyroid disease

3 multiple choice options

77
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Vascular Claudication:

is usually managed non-surgically

3 multiple choice options

78
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Aortic Aneurysm:

Arise most commonly in the infrarenal abdominal aorta

3 multiple choice options

79
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Carotid Artery Stenosis due to atheroma:

Can be managed with surgical endarterectomy

3 multiple choice options

80
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The major risk factors for peripheral occlusive arterial disease include:

Hypertension

81
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Deep vein thrombosis:

Is more common In patients undergoing lower limb surgery

3 multiple choice options

82
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A DVT in the popliteal vein in the leg is most likely to embolise to:

The lungs

3 multiple choice options

83
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The Term that describes leaking of blood from the right ventricle to the right atrium is?

Tricuspid regurgitation

3 multiple choice options

84
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Which of the following is not a risk factor for atherosclerosis arterial disease?

Female gender

3 multiple choice options

85
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The most common material/substance causing embolism is?

Thrombus

3 multiple choice options

86
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Virchow's triad refers to the components predisposing to the pathological process of?

Thrombosis

3 multiple choice options

87
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If a patient with asthma becomes wheezy during an oral surgery procedure, the correct inhaler treatment would be?

Salbutamol

3 multiple choice options

88
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The oxygen content of a room air is?

21%

3 multiple choice options

89
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The key clinical features of hypoxia is?

Cyanosis

3 multiple choice options

90
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The most common type of lung cancer is?

Squamous cell carcinoma

3 multiple choice options

91
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The number of deaths in the UK each Year from lung cancer is?

35000

3 multiple choice options

92
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OSAS is usually treated by?

CPAP

3 multiple choice options

93
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The major cause of chronic lung infection in cystic fibrosis is?

Pseudomonas aeruginosa

3 multiple choice options

94
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A Typical adverse effect of an anticholinergic inhaler such as tiotropium?

Dryness of the mouth

3 multiple choice options

95
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community acquired pneumonia is most commonly caused by?

Streptococcus Pneumonia

3 multiple choice options

96
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A typical case of diffuse lung fibrosis is?

Asbestos

97
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BMI grade 1 lies in the range of?

25-30

3 multiple choice options

98
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Which of the following does not promote gastrooesophageal reflux?

Milk

3 multiple choice options

99
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Crohn's disease?

Is characterised by transmural inflammation

3 multiple choice options

100
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Which of the following is a proton pump inhibitor?

Omeprazole

3 multiple choice options