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Flashcards generated from lecture notes, focusing on vocabulary terms and definitions.
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DNA
A double helix structure responsible for inherited traits, made from billions of base pairs bonded together to a sugar-phosphate backbone.
Nucleotide
Composed of a sugar, a phosphate group, and a nitrogenous base.
Purines
Adenine (A) and Guanine (G) are nitrogenous bases with a double-ring structure.
Pyrimidines
Cytosine (C) and Thymine (T) are nitrogenous bases with a single-ring structure.
Restriction Enzymes
Enzymes that come from bacteria and make cuts in DNA at specific sequences.
Restriction Fragment Length Polymorphisms (RFLPs)
DNA fragments of different lengths resulting from the cutting of DNA by restriction enzymes.
Gel Electrophoresis
A technique used to separate DNA fragments based on size by applying an electric field.
Autopsy
A post-mortem examination to determine the cause and manner of death.
Confidentiality
A set of rules that govern the limits of access to information, or place restrictions on certain types of information, except under specific circumstances.
HIPAA (Health Insurance Portability and Accountability Act)
US legislation that protects the privacy of patient health information.
Polygraph
A test that measures physiological responses to questions to determine truthfulness.
Independent Variable
The variable that is manipulated by the researcher in an experiment.
Dependent Variable
The variable that is measured in an experiment to see if it is affected by the independent variable.
Control
A standard of comparison in an experiment.
Antigens
Substances that can trigger an immune response.
Gene
A unit of heredity that is transferred from a parent to offspring and is held to determine some characteristic of the offspring.
Chromosome
A thread-like structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes.
Eukaryotic Cells
Cells with a nucleus and other membrane-bound organelles.
Prokaryotic Cells
Cells without a nucleus or other membrane-bound organelles.
Cause of Death
The specific injury, disease, or condition that directly caused a person's death.
Manner of Death
The circumstances surrounding a death, such as natural, accidental, suicide, homicide, or undetermined.
Mechanism of Death
he physiological derangement that results in death.
Livor Mortis
The pooling of blood in the body after death, causing a purplish discoloration of the skin.
Rigor Mortis
The stiffening of muscles after death.
Algor Mortis
The cooling of the body after death.
Clinical Empathy
Understanding and sharing the feelings of a patient.
Systolic Blood Pressure
The pressure in the arteries when the heart beats (contracts).
Diastolic Blood Pressure
The pressure in the arteries when the heart is at rest between beats.
BMI (Body Mass Index)
A measure of body fat based on height and weight.
Metabolic Syndrome
A cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes.
Familial Hypercholesterolemia (FH)
A genetic disorder characterized by high cholesterol levels.
Genotype
The genetic makeup of an organism.
Phenotype
The observable characteristics of an organism resulting from the interaction of its genotype with the environment.
Agents of Disease
Biological, chemical, or physical entities capable of causing illness or disease.
Chain of Infection
The sequence of events required for an infection to spread from a reservoir to a susceptible host.
Reservoir
A place where an infectious agent normally lives and multiplies.
Innate Immunity
Non-specific defense mechanisms that come into play immediately or within hours of an antigen's appearance in the body.
Acquired Immunity
Antigen-specific immune response.
Aseptic Technique
A procedure performed under sterile conditions to minimize contamination.
Isolation Streak
A technique used to separate bacteria on a petri dish to obtain pure cultures.
Bacteria Morphology
The shape and structure of bacterial cells (e.g., cocci, bacilli, spirilla).
Gram Stain
A differential staining technique used to classify bacteria based on their cell wall structure.
Primary Assessment ABCs
Airway, Breathing, and Circulation - the initial steps in assessing a patient's condition.
Diffusion
The movement of molecules from an area of high concentration to an area of low concentration.
Osmosis
The movement of water across a semipermeable membrane from an area of high water concentration to an area of low water concentration.
Hypertonic Solution
A solution with a higher solute concentration compared to another solution.
Hypotonic Solution
A solution with a lower solute concentration compared to another solution.
Isotonic Solution
A solution with the same solute concentration as another solution.
Blood Clotting
The process by which blood changes from a liquid to a solid state to stop bleeding.
Triage
The process of prioritizing patients based on the severity of their condition.
Design Process
A systematic approach to problem-solving, involving steps like defining the problem, generating solutions, and testing.
Atherosclerosis
The buildup of plaque inside arteries, leading to narrowing and reduced blood flow.
Stent
A small, expandable mesh tube used to open up blocked arteries.
Xenotransplantation
The transplantation of living cells, tissues, or organs from one species to another.
Stem Cells
Cells that have the ability to differentiate into various cell types.
Ghost Organs
Donated organs that have had their cells removed, leaving a scaffold for stem cells to grow on.
Bioprinting
Creating a scaffold from scratch using bioinks and stem cells.
Primary Prevention
Actions taken to prevent a disease or condition from occurring.
Secondary Prevention
Actions taken to detect a disease or condition early so it can be treated.
Tertiary Prevention
Actions taken to reduce the impact of a disease or condition that has already occurred.
Biomimicry
Copying designs from nature to create new products.
GIS (Geographic Information System)
A tool that helps people communicate and analyze information into a visual presentation (map).
Bioprospecting
The search for plant and animal species and other organisms that may yield medicinal drugs and other commercially valuable compounds.
Blood Spatter Analysis
The examination of bloodstains to determine the events that occurred at a crime scene.
Karyotype
A display of chromosome pairs of a cell arranged by size and shape.
Deletion (mutation)
A mutation in which a section of DNA is lost or deleted.
Insertion (mutation)
A mutation in which extra nucleotide base pairs are inserted into a new place in the DNA.
Inversion (mutation)
A mutation in which a section of DNA is reversed.
Duplication (mutation)
A mutation in which a section of DNA appears twice (duplicated).
Translocation (mutation)
A mutation in which a section of DNA moves from one chromosome to another.
TBI
Traumatic Brain Injury - damage to the brain caused by an external force.
CTE
Chronic Traumatic Encephalopathy - a progressive degenerative disease of the brain found in individuals with a history of repetitive brain trauma.
Pathogen
Any disease-producing agent (especially a virus or bacterium or other microorganism).
Antibiotic
A medicine used to save lives because it destroys harmful bacteria and cures infections.
Virus
A submicroscopic infectious agent that replicates only inside the living cells of an organism.
Prion
Infectious proteins causing neurodegenerative diseases.
Cell Membrane
The semipermeable membrane surrounding the cytoplasm of a cell.
Transcription
The process of making RNA from DNA.
Translation
The process of making proteins from RNA.
Hydrophilic
Having an affinity for water.
Hydrophobic
Having aversion for water.
Receptor
A protein that binds to a specific molecule, triggering a response in the cell.
Endocrine system
System that produces hormones.
Digestive system
System that breaks down food and absorbs nutrients.
Eukaryotic
Cells with a nucleus.
Arteries
Vessels that carry blood away from the heart.
Nervous system
System that controls and coordinates the body's functions through electrical and chemical signals, fast response with short term effects..
Veins
Vessels that carry blood back to the heart.
SpO2
Oxygen Saturation - The measure of oxygen in the blood.
Medical History
A record of a patient's past medical conditions and treatments.
Chief Complaint
The primary reason for a patient's visit.
Neurological Assessment
An evaluation of the nervous system and its functions.
Genetic Mutation
A change in the DNA sequence.
Recessive Gene
A gene whose expression is masked by the presence of a dominant gene.
Dominant Gene
A gene whose expression overshadows the expression of a recessive gene.
Carrier
An individual who carries a recessive gene but does not express it.
Infection
The invasion and multiplication of microorganisms in body tissues.
Drug Delivery
The method of delivering a drug into the body.
Antigen
A toxin or other foreign substance that induces an immune response in the body, especially the production of antibodies.
Antibody
A blood protein produced in response to and counteracting a specific antigen.