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apical pulse
Pulse felt or heard over the apex of the heart. It is measured in the fifth left
intercostal space (between the ribs) about 8 to 9 cm from the midline
cardiac output
The amount of blood pumped from the right or left ventricle per minute
Korotkoff sounds
Arterial sounds heard with a stethoscope during determination of blood
pressure with a cuff
perfusion
The passage of fluid, such as blood, through an organ or tissue
precordium
The anterior region over the heart and the lower part of the thorax; adjective, precordial
pulse pressure
The difference between systolic and diastolic pressure
stroke volume
The amount of blood ejected by the left ventricle with each beat
Valsalva maneuver
Bearing down, as in childbirth or defecation, by attempting to exhale
forcefully with the nose and throat closed. This action has an effect on the
cardiovascular system
bruit
An abnormal sound heard in auscultation
cardiac tamponade
Pathologic accumulation of fluid in the pericardial sac. May result from
pericarditis or injury to the heart or great vessels
ectopic beat
A heartbeat that originates from some part of the heart other than the SA
node
extrasystole
Premature contraction of the heart that occurs separately from the normal
beat and originates from a part of the heart other than the SA node
flutter
Very rapid (200 to 300 bpm) but regular contractions, as in the atria or the
ventricles
hypotension
A condition of lower-than-normal blood pressure
intermittent claudication
Pain in a muscle during exercise caused by inadequate blood supply. The pain disappears with rest
mitral valve prolapse
Movement of the cusps of the mitral valve into the left atrium when the
ventricles contract
occlusive vascular disease
Arteriosclerotic disease of the vessels, usually peripheral vessels
palpitation
A sensation of abnormally rapid or irregular heartbeat
pitting edema
Edema that retains the impression of a finger pressed firmly into the skin
polyarteritis nodosa
Potentially fatal collagen disease causing inflammation of small visceral arteries. Symptoms depend on the organ affected
Raynaud disease
A disorder characterized by abnormal constriction of peripheral vessels in the arms and legs on exposure to cold
regurgitation
A backward flow, such as the backflow of blood through a defective valve
subacute bacterial endocarditis (SBE)
Growth of bacteria in a heart or valves previously damaged by rheumatic fever
tetralogy of Fallot
A combination of four congenital heart abnormalities: pulmonary artery
stenosis, interventricular septal defect, displacement of the aorta to the right, and right ventricular hypertrophy
thromboangiitis obliterans
Inflammation and thrombus formation resulting in occlusion of small vessels, especially in the legs. Most common in young men and correlated with heavy smoking. Thrombotic occlusion of leg vessels may lead to gangrene of the feet. Patients show a hypersensitivity to tobacco. Also called Buerger disease
vegetation
Irregular outgrowths of bacteria on the heart valves; associated with rheumatic fever
Wolff–Parkinson–White syndrome (WPW)
A cardiac arrhythmia consisting of tachycardia and a premature ventricular beat caused by an alternative conduction pathway
cardiac catheterization
Passage of a catheter into the heart through a vessel to inject a contrast
medium for imaging, diagnosing abnormalities, obtaining samples, or
measuring pressure
central venous pressure (CVP)
Pressure in the superior vena cava
cineangiocardiography
The photographic recording of fluoroscopic images of the heart and large
vessels using motion picture techniques
Doppler echocardiography
An imaging method used to study the rate and pattern of blood flow
Holter monitor
A portable device that can record up to 24 hours of an individual's ECG
readings during normal activity
homocysteine
An amino acid in the blood that at higher-than-normal levels is associated
with increased risk of cardiovascular disease
phlebotomist
Technician who specializes in drawing blood
phonocardiography
Electronic recording of heart sounds
plethysmography
Measurement of changes in the size of a part based on the amount of blood contained in or passing through it. Impedance plethysmography measures changes in electrical resistance and is used in the diagnosis of deep vein thrombosis
pulmonary capillary wedge pressure (PCWP)
Pressure measured by a catheter in a branch of the pulmonary artery. It is an indirect measure of pressure in the left atrium
radionuclide heart scan
Imaging of the heart after injection of a radioactive isotope; the PYP
(pyrophosphate) scan using technetium-99 m (99mTc) is used to test for myocardial infarction because the isotope is taken up by damaged tissue; the MUGA (multigated acquisition) scan gives information on heart function
Swan–Ganz catheter
A cardiac catheter with a balloon at the tip that is used to measure pulmonary arterial pressure. It is flow-guided through a vein into the right side of the heart and then into the pulmonary artery
transesophageal echocardiography (TEE)
Use of an ultrasound transducer placed endoscopically into the esophagus to obtain images of the heart
triglyceride
Simple fat that circulates in the bloodstream
ventriculography
X-ray study of the ventricles of the heart after introduction of an opaque dye by means of a catheter
atherectomy
Removal of atheromatous plaque from the lining of a vessel. May be done by open surgery or through the lumen of the vessel
commissurotomy
Surgical incision of a scarred mitral valve to increase the size of the valve
opening
embolectomy
Surgical removal of an embolus
intraaortic balloon pump (IABP)
A mechanical assist device that consists of an inflatable balloon pump inserted through the femoral artery into the thoracic aorta. It inflates during diastole to improve coronary circulation and deflates before systole to allow blood ejection from the heart
ventricular assist device (VAD)
A pump that takes over the function of the left ventricle in delivering blood
into the systemic circuit. These devices are used to assist patients awaiting heart transplantation or those who are recovering from heart failure; most common is a left ventricular assist device (LVAD)
angiotensin-converting enzyme (ACE) inhibitor
A drug that lowers blood pressure by blocking the formation in the blood of
angiotensin II, a substance that normally acts to increase blood pressure
angiotensin receptor blocker (ARB)
A drug that blocks tissue receptors for angiotensin II; angiotensin II receptor antagonist
antiarrhythmic agent
A drug that regulates the rate and rhythm of the heartbeat
beta-adrenergic blocking agent
Drug that decreases the rate and strength of heart contractions; beta-blocker
calcium-channel blocker
Drug that controls the rate and force of heart contraction by regulating calcium entrance into the cells
Coumadin
Drug that inhibits clotting by inhibiting formation of vitamin K, a factor necessary for blood coagulation. Trade name for the generic warfarin
digitalis
A drug that slows and strengthens heart muscle contractions
diuretic
Drug that eliminates fluid by increasing the kidneys’ output of urine. Lowered blood volume decreases the heart’s workload
heparin
Substance that inhibits blood clotting by interfering with the conversion of
prothrombin to thrombin
hypolipidemic agent
Drug that lowers serum cholesterol
lidocaine
A local anesthetic that is used intravenously to treat cardiac arrhythmias
loop diuretic
Drug that increases urine output by inhibiting electrolyte reabsorption in the kidney nephrons (loops)
nitroglycerin
A drug used in the treatment of angina pectoris to dilate coronary vessels
statins
Drugs that act to lower lipids in the blood. The drug names end with -statin, such as lovastatin, pravastatin, atorvastatin
streptokinase (SK)
An enzyme used to dissolve blood clots
tissue plasminogen activator (tPA)
A drug used to dissolve blood clots. It activates production of a substance
(plasmin) in the blood that normally dissolves clots
vasodilator
A drug that widens blood vessels and improves blood flow