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Cardiovascular System Function
Transports nutrients, wastes, and hormones; regulates pH and temperature; protects against infection and blood loss.
Cardiovascular System Structure
Blood, heart, and blood vessels.
Arteries
Vessels carrying blood away from the heart
Veins
Vessels carrying blood to the heart
Circulatory System
Systemic circuit
Circulatory System
Pulmonary circuit
Heart Function
Pump blood.
Heart Structure
Two pumps (right and left), layers of pericardium, myocardium, endocardium; chambers of two atria and two ventricles; valves into and out of ventricles.
Pericardium Layers
Fibrous, parietal, fluid layer, visceral.
Myocardium
Muscular layer of the heart.
Endocardium
Innermost layer of the heart.
Atrioventricular Valves
Tricuspid and bicuspid (mitral).
Semilunar Valves
Pulmonary and aortic
Pericardium Function
Protects the heart and anchors it.
Fibrous Pericardium
Dense and non-flexible connective tissue layer of the pericardium.
Serous Pericardium
Parietal layer (attached to fibrous layer) and visceral layer (outer surface of the heart wall, also known as epicardium).
Pericardial Fluid
Lubricates the space between the visceral and parietal pericardium.
Layers of the Heart Wall (superficial to deep)
The epicardium (visceral pericardium), the myocardium (cardiac muscle tissue), and the endocardium (endothelium).
Upper Chambers of the Heart
Right and left atria.
Lower Chambers of the Heart
Right and left ventricles.
Right Heart
Right atrium and right ventricle; pumps deoxygenated blood from the body to the lungs.
Left Heart
Left atrium and left ventricle; pumps oxygenated blood from the lungs to the body.
Atrioventricular Valves Function
Allow blood to flow from atria into ventricles; prevent blood flowing from ventricles to atria
Outflow (Semilunar) Valves Function
Allow blood to flow from ventricles into arteries; prevent blood flowing from arteries to ventricles
Atrioventricular (AV) Valves
Right = tricuspid valve, left = bicuspid or mitral valve.
Outflow Valves (Semilunar Valves)
The right outflow valve (pulmonary valve) opens into the pulmonary trunk (pulmonary artery). The left outflow valve (also called the aortic valve) opens into the aortic arch (aorta).
Cardiac Muscle Tissue
Connect to and communicate with neighboring cells via gap junctions in intercalated discs.
Autorhythmicity
Form cardiac conduction system; myocytes spontaneously depolarize after repolarizing.
Sinoatrial (SA) Node
Normal pacemaker of the heart, located in the right atrial wall below the superior vena cava.
Cardiac Conduction
Spontaneous Depolarization of autorhythmic fibers in the SA node firing about once every 0.8 seconds, or 75 action potentials per minute
Cardiac Conduction System Pathway
SA node -> Internodal fibers -> AV node -> AV bundle -> Right and Left Bundle Branches -> Purkinje fibers -> regular myocardium in ventricles.
Electrocardiogram (ECG or EKG)
Recording of the electrical changes on the surface of the body resulting from the depolarization and repolarization of the myocardium.
P Wave
Atrial depolarization.
QRS Complex
Atrial repolarization + ventricular depolarization.
T Wave
Ventricular repolarization.
Cardiac Cycle
All events associated with one heartbeat, including diastole (relaxation phase) and systole (contraction phase) of both the atria and the ventricles.
Stroke Volume (SV)
Volume of blood ejected from the left (or right) ventricle every beat.
Cardiac Output (CO)
SV x heart rate (HR).
Cardiac Reserve
Difference between the CO at rest and the maximum CO the heart can generate.
Factors Affecting Stroke Volume
The amount of ventricular filling before contraction (preload), the contractility of the ventricle, and the resistance in the blood vessels (afterload).