Cytosolic innate receptors

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4 Terms

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What do cytosolic innate receptors recognize?

Intracellular cytosolic PAMPs such as viral nucleic acids and bacterial signaling molecules.

2
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What does RIG-1 recognize?

Viral RNA.

3
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What do NOD-like receptors (NLRs) recognize?

Bacterial cell wall components in the cytosol.

4
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What happens when cytosolic innate receptors are activated?

They inhibit the growth of intracellular pathogens and recruit white blood cells to destroy infected host cells.