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What do cytosolic innate receptors recognize?
Intracellular cytosolic PAMPs such as viral nucleic acids and bacterial signaling molecules.
What does RIG-1 recognize?
Viral RNA.
What do NOD-like receptors (NLRs) recognize?
Bacterial cell wall components in the cytosol.
What happens when cytosolic innate receptors are activated?
They inhibit the growth of intracellular pathogens and recruit white blood cells to destroy infected host cells.
