Lecture 5: Endo/Repro Exam 2: Histology Genital system- female I: ovaries, folliculogenesis

prophase I of meiosis I

in the female ovaries at birth, all gametes are arrested in ______

12.7

Menarche mean age:

51.4

Menopause: mean age:

cortex

ovarian follicles are located in what part of the ovaries?

medulla

ovarian blood vessesl are located in what part of the ovaries?

primordial follicle

ID the ovarian cell:
-single layer, flattened follicle cells
-600-800K at birth
-primary oocyte (1° - MI not complete)
-prophase of meiosis I
-duplicated chromosomes (4n DNA)
(post-crossing over)

primordial follicle

ID the ovarian cell stage:

primary (early) follicle

ID the ovarian cell stage:

primary (early) follicle

ID the ovarian cell:
-single layer, cuboidal follicle
cells (FC)
-primary oocyte (1°)
-zona pellucida appears
-prominent basal lamina
-stromal cells begin to
condense around follicle

follicular cells

ID the pink structure:

basal lamina

ID the yellow structure:

zona pellucida

ID the blue structure:

primary (late, multilaminar) follicles

ID the ovarian cell stage:

primary (late, multilaminar) follicles

ID the ovarian cell:
-obvious growth of oocyte
-several layers of follicular cells - called granulosa cells (GC). Possibly pseudostratified
-zona pellucida well developed
-perforated by microvilli from oocyte and granulosa cells
-gap junctions between microvilli

zona pellucida

ID the pink structure:

granulosa cells

ID the yellow structure:

follicular antrum

ID the location in which the pink box is sitting in:

secondary (antral) follicles

ID the ovarian cell stage:

future corona radiata

ID the blue structure:

cumulous oophorus

ID the pink structure:

granulosa cells

ID the yellow structure:

follicular antrum

ID the red region of the follicular cell:

granulosa cells

ID the orange region of the follicular cell:

theca interna

ID the yellow region of the follicular cell:

theca externa

ID the green region of the follicular cell:

stroma

ID the blue region of the follicular cell:

theca interna

this region synthesizes androgens (via LH stimulation):

theca externa

this region contains myofibroblasts that expel the ovum during ovulation:

Mature vesicular follicle (Graafian follicle)

ID the ovarian cell stage:

Mature vesicular follicle (Graafian follicle)

ID the ovarian cell stage:
-secondary (2°) oocyte (meiosis I
[reduction division] has completed)
-unequal cytokinesis gives rise to
first polar body
-still 2n DNA - will become 1n
at the completion of meiosis II*)

corpus luteum

-breakdown of follicle basement membrane
-ingrowth of blood vessels
-proliferation and infolding of GCs and theca interna

corpus luteum

ID the ovarian cell stage:

granulosa lutein cells

ID the yellow structures:

theca lutein cells

ID the blue structures:

progesterone

Rising _______ levels will stimulate endometrial gland secretion

corpus albicans

ID the ovarian cell stage:

corpus albicans

-form each cycle and following pregnancy
-after ~10d degeneration leads to drop in progesterone

follicular atresia

death and resorption of the follicle:

glassy membrane

ID the structure:

basement membrane

the glassy membrane is the former ______