ochem 2 exam 3 true false

Fischer esterification of carboxylic acids can be catalyzed by acid or by base.

f

Amine N-H hydrogens are more acidic than amide N-H hydrogens

f

Acid catalyzed a-bromination of ketones proceeds via an enol tautomer.

True

Reduction of 2-butanone by LiAH4 gives a racemic mixture of 2-hydroxybutane.

True

The driving force for reduction of a ketone by hydrazine is formation of N2 gas.

True

Nucleophilic acyl substitution is a ———- reaction (rate=k… ) and the ? is rate-determining.

biomlecular, first step = addition

LDA reacts with 2-butanone to give an equimolar mixture of both the more- substituted and less-substituted enolates

False

Grignard reagents, like H3C-MgBr, add 1,2 to a,b-unsaturated carbonyl

True

Base-catalyzed racemization of a chiral center alpha to a carbonyl involves

reversible formation and re-protonation of a planar enolate anion.

True