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Evolution
the changing of characteristics in a population over time (NOT in individuals)
What are the two theories of how biodiversity occurs?
Special creation and evolution
catastrophism
the world came about suddenly and quickly through sudden dramatic changes (great flood), related to special creation
gradualism
large effects come from small changes over long time periods
Uniformitarianism
rates of change have been the same throughout history
Was Darwin the first person to propose evolution?
No, he only proposed the mechanism
Lamarckism
inheritance of acquired traits, doesn’t explain the hierarchy of species
Who discovered the correct mechanism for evolution?
Codiscovered by Wallace and Darwin
Natural selection
the process that promotes maintenance and spread of traits promoting survival and fecundity
What 3 things will always cause evolution?
individuals vary, variation has a heritable component, and individuals with certain attributes survive and reproduce best
What two ideas are the foundation of modern biology?
gradualism and evolution by natural selection
What ideas came about during the Darwinian revolution?
evolution is not purposeful or goal-driven
an intelligent designer is not needed for biodiversity
evolution does not necessarily favor more complex/bigger
Artificial selection
process of changing traits of domestic animals by humans by promoting the survival and reproduction of individuals with desirable traits
What three elements cause evolution via natural selection?
individuals vary
variation has a heritable component
humans choose to to breed individuals with desired traits
orthogenesis
evolution is a straight line leading to humans (less to more complex)
Who were Darwin’s two bulldogs?
Thomas Huxley and Alfred Wallace
Thomas Huxley
Stood in for Darwin during public debates
Saltation
Evolution occurs in big steps, new species are formed without intermediates
Hopeful Monsters
brand new, highly functioning organisms resulting from a single evolutionary step (saltation)
Thomas Hunt Morgan
developed concepts of Mendelian genetics with fruit flies
Bean Bag Genetics
genes are discrete traits of inheritance distributed on chromosomes, mutation and crossing over of genes is the source of new traits. Fails to consider complex interactions of genes
Mutationists
evolution occurs via mutation without natural selection
What groups did biology divide into by the 20th century?
lamarckists, saltationists, mutationists, and darwinians
What did the new synthesis combine?
Mendelian genetics and natural selection
What is the raw material of natural selection?
Variation
Heritable Variation
Variation arising from differences in traits that are passed from parents to offspring
What are the sources of heritable variation?
Mutation and gene flow
Mutation
random changes to genetic code
Gene flow
genes that code for traits moving from one population to another
Fitness
lifetime reproductive success of an individual
Example of fitness consequences
mouse color affecting predation based on the habitat it lives in
Adaptation
attunement to the environment or a trait that increases fitness in a particular environment
Directional selection
selection away from the current phenotype to a single new one or selection for the replacement of one allele with another
purifying/stabilizing selection
selection for the current phenotype
Disruptive Selection
selection for 2 distinct phenotypes, selection against intermediate for 2 different allele states
Example of Natural selection
light colored moth, then the industrial revolution made everything dark, all the moths became dark- directional selection
exaptation
trait that evolved for one reason but is now used for another
Example of exaptation
feathers evolved for insulation but are now used for flight, see red to be red
gene
sequence of dna that specifies a functional product
Allele
version of a gene
locus
location of a gene on a chromosome
Genotype
combination of alleles that an individual has at a locus
Phenotype
observable characteristics of an organism
What conclusions did mendel come to?
inheritance is particulate- individuals have two alleles and can be homo/heterozygous
some alleles are dominant and some are recessive
the law of segregation
the law of segregation
alleles at locus separate into 2 gametes
Why did Mendel work in an ideal scenario?
each trait was determined by 1 gene
each gene was unlinked
each trait was controlled by a simple dominant/recessive system
Linkage disequilibrium
nonrandom association of alleles on different loci
Law of independant assortment
alleles of each gene segregate independently
Hardy Weinburg Model assumes
there is no evolution
What does the Hardy Weinburg model allow the calculation of?
The gene frequency in the following generation
What is the hardy weinburg equation?
1=p²+2pq+q²
What are the old and new definitions for evolution (genetically)?
old: change in characteristics of a population over time
new: change in gene frequency of a population over time
Darwinian fitness
reproductive success relative to the average reproductive success in a population
Selection Coefficient
fitness reduction of one genotype relative to another
What are the 3 theories for why there is heterozygosity in the wild?
mutation selection balance, heterozygote advantage, and frequency dependent selection
Mutation selection balance
natural selection perpetually removes less fit alleles, mutation perpetually removes less fit alleles, mutation perpetually introduces more fit alleles, deletarious alleles always exist at low frequencies
Heterozygote advantage
the heterozygote is the most fit, for example sickle cell anemia
frequency dependent selection
fitness of alleles changes with allele frequency. High fitness when rare, low when common.
Genetic drift
evolution due to chance events AKA sampling error
Founder events
new populations are founded with few individuals, there is almost always a change in gene frequency. Examples are tay-sachs and huntingtons