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Agglutination
Clumping of microorganisms or blood cells, typically due to an antigen-antibody interaction/reaction.
Antibodies
Proteins secreted by white blood cells that attach to antigens, keeping them from harming the body. Y-shaped proteins that attach to particular kinds of antigens to destroy them (secreted by WBC)
Antigen-antibody response
reaction in which anti-bodies attach to specific antigens; causes agglutination in cross blood-type transfusions
Antigens
any foreign substance or cell in the body that reacts with antibodies (trigger the attack of antibodies in the immune response). foreign substances that trigger the attack of antibodies in the immune response
Cell-surface protein
Proteins embedded in the cell membrane used for cell transport
Lines of convergence
a two-dimensional view of the intersection of lines formed by drawing a line through the main axis of at least two drops of blood that indicates the general area of the source of the blood spatter
point of origin
a three-dimensional view formed using lines of convergence and angles of impact of at least two different drops of blood to identify the source and location of blood splatter (tangent angle of impact)
Red Blood Cells
erythrocytes - donut-shaped cells that carry oxygen throughout the body
satellite drop of blood
secondary drop formed when some blood breaks free from the main contact drop of blood
White blood cells
leukocytes - cells that police the body by destroying foreign materials.
Rh factor
presence or lack of antigens on the surface of red blood cells, which causes a reaction between Rh-positive blood and Rh-negative blood
ABO blood typing
Method of identifying which self-recognition proteins of types A and B are at the surface of an individual's red blood cells; the absence of either type is designated O.
Plasma
liquid portion of blood which contains platelets
Platelets
thrombocytes which carry out the fundamental task of healing through clotting.
Spines
the pointed edges of a stain that radiate out to form the spatter. More present on a non-smooth surface. Indicates the blood dropped at an angle.
Blood spatter analysis
a field of forensic science that deals with the physical properties of blood and the patterns produced under different conditions as a result of various forces applied to the source of blood
blood spatter patterns
Helps establish the events that took place; help distinguish between an accident and foul play.
list the types of blood spatter patterns:
Passive fall
Arterial spurts
Splashes
Smears
Trails of blood
Pools or blood
surface tension
the force that acts on the surface of a liquid and that tends to minimize the area of the surface
cohesion
Attraction between molecules of the same substance
adhesion
An attraction between molecules of different substances
ELISA blood Test
a common laboratory testing technique that detects and counts certain antibodies, antigens, proteins and hormones in bodily fluid samples. This includes blood, plasma, pee, saliva (spit) and cerebrospinal fluid (CSF). "ELISA" stands for "enzyme-linked immunosorbent assay
Luminol
the most sensitive chemical test that is capable of presumptively detecting bloodstains diluted to as little as 1 in 100,000; its reaction with blood emits light and thus requires the result to be observed in a darkened area. Blue glow when contact w blood
composition of blood
55% plasma, 45% formed elements - plasma, red blood cells, white blood cells, platelet
red blood cell function
transport oxygen and carbon dioxide
white blood cell function
Phagocytosis (neutrophils and monocytes) and antibody formation (lymphocytes) - kills bacteria and viruses
Define Red Blood Cells
erythrocytes; the most abundant cells in our blood, they are produced in the bone marrow and contain a protein called hemoglobin which carriers oxygen to our cells. Responsible for the transmission of carbon dioxide waste back to the lungs.
Define White Blood Cells
leukocytes; they are part of the immune system and destroy infectious agents called pathogens.
define plasma
this is the yellowish liquid portion of the blood that contains electrolytes, nutrients, and vitamins as well as hormones, clotting factors and proteins such as antibodies to fight infection.
define platelets
thrombocytes, the clotting factors that are carried in the plasma. They clot together in a process known as coagulation to seal a wound and prevent loss of blood.
coagulation
process of blood clotting
how many liters of blood does an average adult have?
5 liters, 7-8% of body weight
What is considered a living tissue?
Blood
list what blood does:
carries oxygen and nutrients to all parts of the body, carries CO2 and waste to the lungs, kidneys and liver, fights against infection, and help heals wounds
how many RBC are there in 2-3 drops of blood?
1 billion
For every ___ red blood cells there are platelets and WBC
600;40;1
When are blood types established?
before birth by specific genes inherited by parents, you inherit one gene from your father and one from your mother
agglutinogens
antigens on the surface of the RBC that is the basis for blood typing based on composition arrangement
when was blood typing discovered?
1900
who discovered blood typing?
Karl Landsteiner
what does blood typing do (basic terms)
identifies the presence or absence of particular proteins embedded on the cell
Why is blood typing used frequently
it is quicker and cheaper than dna profiling
what type of evidence is blood
class evidence (can link and exclude suspects from crimes)
List the Blood types
A+, A-, B+, B-, AB+, AB-, O+, O-
list the blood types from most common to least common
O (43%), A (42%), B (12%), AB (3%)
How many people have the rhesus factor?
85%
universal recipient
Type AB blood
universal donor
Type O blood
Blood transfusion
whole blood or cells are taken from a donor and infused into a patient
whole blood or cells are taken from a donor and infused into a patient
blood falling directly to floor at 90 degree angle will produce circular drops, w secondary satellites
Arterial Spurts
Found on walls or ceilings, Large patterns under pressure from an artery, but with less volume; distinct rises and falls of blood pressure apparent. Caused by pumping action of the heart
Splashes
A bloodstain pattern created from a large volume of liquid blood falling onto a surface
smears
left by bleeding victim depositing blood as he or she touches or brushes against a wall or furniture
spurt
trails of blood left by a bleeding victim as he/she moves from one location to another. Droplets are round or smeared
pool of blood
occurs when blood collects in a level (not sloped) and undisturbed place
Harder less porous surface
the less spatter results
rough surfaces
irregularly shaped stains with serated edges and satelite spatter
list harder surfaces
glass, paper, hardwood
List rougher surfaces
carpet, tile, cloth
directionality of the angle of impact
The direction of travel of blood striking an object may be discerned because the pointed end of a bloodstain always faces its direction of travel
gunshot spatter
bloodstain characterized by fine forward spatter from an exit wound and backward spatter from an entrance wound
cast off spatter
created when a blood-covered object flings blood in an arc onto a nearby surface
arterial spray spatter
caused by an injury to the heart or a main artery and the pressure of the continuing pumping
a void pattern
An area within a deposited spatter pattern that is clear of spatter, caused by an object or person blocking the area at the time of the spatter's deposition.