syncope

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Last updated 5:45 PM on 9/13/26
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4 Terms

1
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Define

Def: transient loss of consciousness accompanied by loss of postural tone, followed by complete resolution without intervention.

2
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Causes

[1] Cardiac related syncope:

Structural cardiac lesion → Limit heart's ability to ↑ cardiac output

  • hypertrophic cardiomyopathy

  • aortic stenosis

  • pulmonary embolism

  • MI

Dysrhythmia → sudden and without prodrome

  • ventricular tachycardia

  • Torsades des pointes

  • supraventricular tachycardia

  • bradycardia

  • Brugada or QT syndrome → in young people

[2] Vasovagal syncope:

symp: dizziness, nausea, pallor, diaphoresis, \downarrow vision

sign: hypotension, bradycardia

hx: phlebotomy, prolong standing in warm place, fear

[3] Situational syncope:

autonomic reflex response from physical stimulus

  • micturition, defecation, extreme coughing


4. Carotid Sinus Hypersensitivity

  • Hx of shaving, head turning, wearing constricting collar

5. Orthostatic Syncope

  • Sudden change in posture after recumbence is associated with inadequate compensatory increase in HR and peripheral vascular resistance

  • Due to ↓ intravascular volume or poor vascular tone

  • Causes:

    • Peripheral neuropathy

    • Spinal cord injury

    • Medication side effect

6. Neurologic Syncope

  • Brainstem ischemia or vertebrobasilar insufficiency → diplopia, vertigo, focal neurological deficits, nausea

  • Intermittent obstruction of brachiocephalic or subclavian artery → hx of upper extremity exercise

  • Subarachnoid hemorrhage → headache, trauma


3
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Dd

D.D - Seizures

Brief tonic-clonic movement

Postictal state

Tongue biting

Incontinence

Epileptic aura

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Diagnosis

Diagnosis

  • Sudden without warning → suggest dysrhythmias

  • Preceding exertion → structural cardiopulmonary lesion

  • Palpitation or chest pain → cardiac etiology

  • Vertigo or focal weakness → neurologic cause

  • Back or Abd. pain → leaking abdominal aortic aneurysm or ruptured ectopic pregnancy

  • Orthostatic hypotension with SBP drop 20 mmHg upon standing → vasovagal syncope

  • BP differential between upper extremities > 20 { mmHg} → subclavian steal syndrome

  • ECG → ischemia or dysrhythmia

    • prolonged QT interval → torsades des pointes

    • PR interval shortening with delta wave → Wolff-Parkinson-White syndrome