Campbell Chapter 12 - The Cell Cycle

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Cell division

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60 Terms

1

Cell division

The ability of organisms to produce more of their own kind.

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2

Omnis cellula e cellula

Rudolf Virchow's concept that all cells arise from pre-existing cells.

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3

Cell cycle

The series of events that a cell goes through as it grows and divides.

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4

Chromosomes

Structures made of DNA and proteins that contain genetic information.

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5

Mitosis

The division of genetic material in the nucleus of a cell.

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6

Cytokinesis

The division of the cytoplasm of a cell.

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7

Sister chromatids

Joined copies of the original chromosome.

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8

Centromere

The region where sister chromatids are attached most closely to each other.

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9

Somatic cells

Non-reproductive cells that have 23 pairs of chromosomes.

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10

Gametes

Reproductive cells that have half as many chromosomes as somatic cells.

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11

Chromatin

The form of chromosomes when a cell is not dividing.

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12

Prophase

The first stage of mitosis where chromatin fibers condense into discrete chromosomes.

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13

Prometaphase

The stage where the nuclear envelope fragments and microtubules invade the nuclear area.

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14

Metaphase

The stage where chromosomes align at the metaphase plate.

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15

Anaphase

The stage where sister chromatids separate and move towards opposite ends of the cell.

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16

Telophase

The stage where daughter nuclei form and chromosomes become less condensed.

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17

Cleavage furrow

The indentation that forms during cytokinesis in animal cells.

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18

Cell plate

The structure that forms during cytokinesis in plant cells.

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19

Binary fission

The process of cell division in bacteria and archaea.

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20

Evolution of mitosis

The hypothesis that mitosis evolved from simpler prokaryotic mechanisms of cell reproduction.

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21

Hypothesis

Ignores potential intermediate mechanisms used by extinct species

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22

Chromosomes

Structures that carry genetic information in the form of DNA

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23

Cleavage furrow

Indentation that forms during cytokinesis in animal cells, leading to cell division

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24

Cell plate

Structure formed during cytokinesis in plant cells, contributing to cell division

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25

S phase

Stage of the cell cycle where DNA replication occurs and chromosomes consist of two identical chromatids

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26

Tubulin

Protein involved in the formation of microtubules, important for mitotic spindle formation and chromosome separation in eukaryotic cell division

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27

Actin

Protein involved in cytokinesis, aiding in the formation of the cleavage furrow or cell plate

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28

Kinetochore

Protein structure located on the centromere of a chromosome, serving as a connection point for microtubules during cell division

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29

Cell cycle

The series of events that take place in a cell leading to its division and duplication

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30

Cell cycle control system

Set of molecules that regulate the sequential events of the cell cycle

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31

Cyclins

Proteins that fluctuate in concentration throughout the cell cycle and are involved in regulating cell cycle progression

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32

Cyclin-dependent kinases (Cdks)

Kinases that are attached to cyclins to become active and regulate cell cycle events

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33

Cell cycle checkpoints

Points in the cell cycle where stop and go-ahead signals can regulate the progression of the cycle

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34

G1 checkpoint

Checkpoint in the cell cycle where a cell receives a go-ahead signal to complete the cycle and divide

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35

G0 phase

Phase in the cell cycle where cells exit the cycle and do not divide

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36

Cancer cells

Cells that exhibit loss of cell cycle controls and can go on dividing indefinitely

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37

Metastasis

Spread of cancer cells from the original tumor to other parts of the body

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38

Chemotherapy

Treatment for cancer that interferes with specific steps in the cell cycle to inhibit cell division

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39

Benign tumors

Tumors that remain at the original site and can be removed by surgery

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40

Malignant tumors

Tumors that include cells that can spread to new tissues and impair organ functions

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41

Histogram

A graphical representation of data that shows the distribution of cells among different cell cycle phases.

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42

Cell cycle phases

The different stages that a cell goes through during its life cycle, including G1, S, G2, and M phases.

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43

Treated sample

A sample of cells that has been subjected to a specific treatment or intervention.

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44

Stem cell-derived inhibitor

A substance derived from stem cells that can halt or slow down the progression of the cell cycle in cancer cells.

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45

G1, S, and G2 phases

The three phases of the cell cycle where DNA replication, growth, and preparation for cell division occur.

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46

Mitotic spindle

A structure made up of microtubules that controls the movement of chromosomes during mitosis.

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47

Cyclin-dependent kinases (CDKs)

Enzymes that are activated by the protein MpF and play a crucial role in regulating the cell cycle.

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48

Receptor tyrosine kinases

Proteins that trigger cell division by activating signaling pathways involved in cell cycle progression.

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49

Interdisciplinary collaboration

Collaboration between different scientific disciplines to gain a comprehensive understanding of cancer and develop effective treatments.

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50

Model organisms

Organisms, such as fruit flies, that are used in scientific research to study biological processes and diseases like cancer.

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51

Cytokinesis

The process of dividing the cytoplasm of a cell after mitosis, resulting in the formation of two daughter cells.

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52

Binary fission

The process of cell division in bacteria, where the chromosome replicates and the daughter chromosomes move apart.

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53

Cell cycle control system

A molecular system that regulates the progression of the cell cycle, ensuring proper cell division.

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54

Checkpoints

Specific points in the cell cycle where the progression is halted until certain conditions are met.

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55

Density-dependent inhibition

The phenomenon where cells stop dividing when they become too crowded, preventing overgrowth.

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56

Anchorage dependence

The requirement for cells to be attached to a surface in order to divide.

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57

Cancer cells

Cells that have lost the ability to regulate their cell cycle and divide uncontrollably, forming tumors.

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58

Metastasis

The spread of cancer cells from the primary tumor to other parts of the body, forming secondary tumors.

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59

Cell plate

A structure that forms during cytokinesis in plant cells and eventually develops into a new cell wall.

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60

Genetically identical daughter cells

The result of most cell divisions, where the two daughter cells have the same genetic material as the parent cell.

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