a small cylindrical organelle which occur in pairs; located near the nucleus in animal cells; involved in the production of spindle fibres during cell division.
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Centrosome
organelle situated near the nucleus in animal cells, involved in the formation of the spindle prior to nuclear division.
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Chloroplast
organelle that is the site of photosynthesis and contains chlorophyll.
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Contractile vacuole
a small vesicle in the cytoplasm of many freshwater protists that expels excess water.
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Cytoplasm
fluid that fills each cell and is enclosed by the plasma membrane.
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Cytoskeleton
a microscopic network of protein filaments and tubules in the cytoplasm that give cells shape and which are for internal organization.
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Differentiation
process by which cells become specialized, when some genes and not others are expressed in a cell's genome.
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Electron microscope (EM)
microscope in which a beam of electrons replaces light so the powers of magnification and resolution are correspondingly much greater.
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Endoplasmic reticulum
system of branching membranes in the cytoplasm of eukaryotic cells, existing as rough ER (with ribosomes) or as smooth ER (without ribosomes).
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Eukaryote
group of organisms that have a nuclear membrane surrounding their genetic material, i.e., they have a true nucleus.
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Extracellular matrix (ECM)
a large network of proteins and other molecules that surround, support and give structure to cells and tissues in the body.
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Egg/ovum (plural, ova)
a female gamete.
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Embryo
an organism in the earliest stages of growth, when its basic structures are being formed.
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Embryonic stem cell
undifferentiated cell in early-stage embryo, capable of continual cell division and of developing into all the cell types of an adult organism.
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Flagellum (plural, flagella)
a long, thin structure occurring singly or in groups on some cells and tissues; used to propel unicellular organisms and to move liquids past anchored cells (flagella of prokaryotes and eukaryotes have a different internal structure).
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Freeze etching
preparation of specimens for electron microscope examination by freezing, fracturing along natural structural lines and preparing a replica.
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Gamete
a haploid male or female sex cell that is able to unite with another of the other sex to form a zygote.
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Golgi apparatus
a stack of flattened membranes in the cytoplasm, involved in the processing, modifying and packaging of molecules.
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Lysosome
membrane-bound vesicles, common in the cytoplasm, containing digestive enzymes.
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Magnification
how many more times larger an object appears.
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Microfilament
the thinnest class of the cytoskeletal fibres, made of solid rods of globular protein called actin.
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Micro-organism
a living organism that cannot be seen by the naked eye, such as bacteria, protists and single-celled fungi.
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Microtubule
tiny, hollow protein tube in cytoplasm (e.g. a component of the spindle).
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Mitochondrion (pl. mitochondria)
organelle in eukaryotic cells, site of Krebs cycle and the electron-transport pathway.
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Motile
capable of locomotion (whole organism movement).
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Multicellular
consisting of many cells (e.g. animals, plants and most fungi).
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Multinucleate
a cell that has two or more nuclei.
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Multipotent
can create, maintain and repair the cells of one particular organ or tissue.
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Nuclear envelope
a lipid bilayer surrounding the genetic material of the cell, containing nuclear pores that control the movement of molecules between the inside of the nucleus and the cytoplasm.
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Nuclear pore
organized gaps in the nuclear membrane; exit points for mRNA.
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Nucleolus
compact region of nucleus where ribosomes are synthesized.
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Nucleus
largest organelle of eukaryotic cells; controls and directs the activity of the cell.
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Organ
a part of an organism, consisting of a collection of tissues, having a definite form and structure, and performing one or more specialized functions.
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Organelle
a unit of cell substructure.
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Plasma membrane
the membrane of lipid and protein that forms the surface of cells; constructed as a fluid mosaic membrane.
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Plastid
an organelle containing pigments (e.g. chloroplast).
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Pluripotent
able to develop into many different types of cells or tissues in the body, except for becoming placental cells or totipotent stem cells.
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Post-transcriptional modification
changes that occur to a newly transcribed mRNA, after transcription has occurred and prior to its translation into a protein.
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Prokaryote
unicellular organism without a true nucleus; they have a loop of naked DNA.
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Proliferation
increase in the number of cells as a result of cell growth and cell division.
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Protists
eukaryotes consisting of single-celled organisms.
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Resolution
the amount of detail that can be seen.
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Sperm (spermatozoa)
motile male gametes of animals.
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Spindle
structure formed from microtubules, associated with the movements of chromosomes in mitosis and meiosis.
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Stem cell
undifferentiated cell in embryo or adult that can undergo unlimited division and can give rise to one of many different cell types.
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Stem cell niche
specific microenvironments in the body that either maintain the stem cells or promote their proliferation and differentiation.
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Striated
muscle tissue that is marked by alternating dark and light bands.
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Tissue
collection of cells of similar structure and function.
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Tonoplast
membrane around the plant cell vacuole.
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Totipotent
capable of giving rise to any cell type in an organism, including making more totipotent stem cells and making the cells that become the placenta.
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Ultrastructure
fine structure of cells, determined by electron microscopy.
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Unicellular
consisting of a single cell (e.g. prokaryotes, protists and some fungi).
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Vacuole
fluid-filled space in the cytoplasm, especially large and permanent in plant cells.
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Vesicle
membrane-bound sac.
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Transcription
the synthesis of messenger RNA using a DNA template.
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Translation
the information of mRNA is decoded into protein (amino acid sequence).