MED ORG LEC - Endocrine Drugs (ATP FINALS)
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32 Terms
Organification
A reaction in the thyroid gland where iodide is transformed into MIT & DIT
Thyroxine
Name of this hormone?
T4
Other name of Thyroxine
T3
Other name of Triiodothyronine
Hypothyroidism
Therapeutic use of Thyroxine (T4)
Methimazole
Name of this structure?
Hyperthyroidism
Hypothyroidism or Hyperthyroidism?
Exophthalmos
Hyperthyroidism
Hypothyroidism or Hyperthyroidism?
Increased metabolism
Hypothyroidism
Hypothyroidism or Hyperthyroidism?
Reduced appetite
Glycolysis
A metabolic effect of insulin
Glulisine
A rapid-acting insulin analog (B3 Val to Lys; B2a Lys to Glu)
Less ADR
An advantage of 2nd Generation Sulfonylurea
TRUE
True or False?
Pramlintide is a semisynthetic analogue of amylin.
TRUE
Pramlintide suppresses glucagon action
SGLT2 inhibitor
Classification of this structure?
Blocks transporter for glucose reabsorption
How does this drug help in the treatment of diabetes
Aldosterone
Name of this structure?
TRUE
True or False?
Aldosterone can be used for Addison’s disease
FALSE
True or False?
Substitution in the 16-C can increase aldosterone’s activity
FALSE
True or False?
3-keto and saturation in Carbons 4 and 5 is essential for activity of aldosterone
FALSE
True or False?
Halogenation in carbons 6 and 9 can decrease aldosterone’s activity
Aldosterone
Used for diagnosing Conn’s syndrome
Flutamide
A trifluoromethylphenyl derivative
Etidronate
Used for Osteoporosis (bone-related)
Saxagliptin
An alpha amino acyl moeity (pancreatic hormone)
Finasteride
Name of this structure?
Finasteride
Used for male patterned baldness
Progesterone
Hormone responsible for thickening of endometrium lining
FSH
Hormone that stimulates follicle (egg) development
Luteal Phase
Phase where the uterus is being prepared for possible pregnancy by corpus luteum
Follicular Phase
Phase where follicles in the ovary mature and endometrial lining begins to regenerate
Demethylation at 19-C
Structural modification that does not improve pregnancy activity