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- yourself --> through history since often non-specific history and clinical signs
What is the best tool for working up muscle disease cases?
- duration
- intermittency
- triggers
- exercise schedule
- diet, pasture, housing, plants (box elder)
- medication
- vaccination --> flu or stranges
- other animals
What might you want to ask an owner with a horse with muscle issues?
1. at rest to see if its square, size, shape symmetry, fasciculation (elbow or rear legs)
2. during exercise: walk/trott, gait or lameness, weakness, stiffness or pain
How do you want to inspect the horse if its having muscle issues?
- muscle tone
- consistency or sensitivity
- swelling, atrophy, heat
- comparison of both sides
How do you want to palpate a horse if its having muscle issues?
- percussion myotonia (pic is after percussion)
- lumbar = extension
- gluteal = flexion
How do you want to percuss the horse if its having muscle issues?

- CK
- AST
- LDH
What are the enzymes seen with muscle membrane damage, in horses?
- increase after the injury = will be delayed
- CK is quick and spikes after 4-6 hours
- LDH and ASK is slow and spikes 24-48 hours
When do we want to look at muscle enzymes in a horse with muscle disease?
- a horse after training
What does a CK of 500 mean?
- a horse with extreme fatigue
What does a CK of 1,000 - 10,000 mean?
- a horse with rhabdomyolysis
What does a CK of 10,000 - 100,000 mean?
true
True or false
only large increase of muscle enzymes mean disease and you need a base line value before testing
- NEVER in a horse with overt clinical signs
- mild exercise in affected horses, is often enough to induce changes in muscle enzymes = 15 - 30 mins with a blood sample at rest and take blood 4-6 hours and 24-48 hours later
When can you do an exercise test to see if muscle rise?
- myoglobinuria
- increased CREAT
- electrolyte imbalance
What might your U/A look like in a horse with a muscle disease?
- bergstroem needle
- punch
- excision = best way
What are methods to do a muscular bx?
true
True or false
you should always know how to do the biopsy and know where to send a muscle biopsy before taking it
- semimembranosus
- gluteus medius
- sacrocaudalis dorsalis
What muscles do we commonly take bx from in horses?