Glial Cells and CNS Non-Neoplastic Lesions

Flashcards based on key concepts related to glial cells and non-neoplastic lesions in the CNS.

What are the two main types of cells in the central nervous system (CNS)?

Glial cells and Neurons.

What is the function of astrocytes in the CNS?

Astrocytes form the blood-brain barrier and assist in healing.

Which glial cells form the myelin sheath in the CNS?

Oligodendrocytes.

What are microglia known as in the CNS?

Tissue macrophages.

What is the IHC marker for glial cells?

Glial fibrillary acidic protein (GFAP).

What kind of necrosis is associated with brain injury?

Liquefactive necrosis.

What are gemistocytic astrocytes characterized by?

They are densely eosinophilic with glassy cytoplasm.

What do Rosenthal fibers consist of?

Dense, pink, thick, elongated fibers made up of heat shock protein (HSP) and ubiquitin.

Which glial cells form the myelin sheath in the peripheral nervous system (PNS)?

Schwann cells.

What stain is used for myelin in histological studies?

Luxol fast blue.