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3 major functions of the nervous system
1. sensory input
2. integration
3. motor output
2 main subdivisions of the nervous system
1,central nervous system (brain and spinal cord)
2, peripheral nervous system (all nerves)
What is integration?
thinking
What are the two divisions of the PNS?
sensory (afferent) and motor (efferent)
What are glia?
supporting cells, specialized connective tissue cells that support neurons
Neurons
nerve cells that is amitotic (no ability to divide)
Astrocytes
star-shaped cells that anchor small blood vessels to neurons
Microglia
Act as phagocytes, eating damaged cells and bacteria, act as the brains immune system (CNS)
Ependymal cells
line cavities of the brain and spinal cord, circulate cerebrospinal fluid via cilia (CNS)
Oligodendroglia
glial cell that produces myelin sheath (CNS_
Schwann cells
coil around the axon and are responsible for the formation of myelin, adjacent schwann cells don't touch
Satellite cells
hold neurons close to blood vessels in PNS
Soma
cell body
Dendrites
processes that extend from cell body like branches, receive signals from other neurons and bring them toward the cell body
Axon
process that conducts impulses away from the nerve cell
Axon terminal
The endpoint of a neuron where neurotransmitters are stored
axon hillock
Cone shaped region of an axon where it joins the cell body.
myelin sheath
fatty substance that protects and insulates electrical impulse of the axon, also increases impulse transmission speed
Nodes of Ranvier
a gap in the myelin sheath of a nerve, between adjacent Schwann cells.
5 steps of exciting a neuron
1. Cell membrane at rest= polarized (-70mV)
2. Stimulus= excited neuron, becomes depolarized
3. Depolarization= AP (nerve impulse) (-55mV to 30 mV)
4. Repolarization= back to resting potential
5. Back to resting Potential (-70mV)
reflex arc
receptor, sensory neuron, integration center, motor neuron, effector
patellar reflex
knee jerk
pupillary reflex
both pupils constrict when light is directed at one eye, useful for checking brain stem function and drug use
flexor reflex
moves a limb away from a painful stimulus
plantar reflex
elicited touching the soles of the feet. toes curl downward
Babinski reflex
in response to the sole of the foot being stroked, a big toe moves upward or toward the top surface of the foot and the other toes fan out, useful in checking for motor cortex or corticospinal tract damage
Actions of Neurotransmitters
-excitatory (cause depolarization)
-inhibitory (reduce ability to cause action potential)
-direct (bind to and open ion channels provoking a rapid action potential change)
-indirect (no direct contact with ion channels, long-lasting effects)