chapter 42

Which of the following is a barrier against pathogens provided by the skin?

Desiccation

Although interferons have several effects, they are particularly useful against infections with which type of pathogen?

Viruses

Which organelle do phagocytes use to digest engulfed particles?

Lysosome

Which innate immune system component uses MHC I molecules directly in its defense strategy?

NK cells

Which of the following is both a phagocyte and an antigen-presenting cell?

Macrophage

Which immune cells bind MHC molecules on APCs via CD8 coreceptors on their cell surfaces?

CTLs

What “self” pattern is identified by NK cells?

Missing self

The acquired ability to prevent an unnecessary or destructive immune reaction to a harmless foreign particle, such as a food protein, is called .

Immune tolerance

Upon reexposure to a pathogen, a memory B cell can differentiate to which cell type?

Plasma cell

Foreign particles circulating in the blood are filtered by the .

Spleen

The structure of an antibody is similar to the extracellular component of which receptor?

BCR

The first antibody class to appear in the serum in response to a newly encountered pathogen is .

IgM

What is the most abundant antibody class detected in the serum upon reexposure to a pathogen or in reaction to a vaccine?

IgG

Breastfed infants typically are resistant to disease because of .

Passive immunity

Allergy to pollen is classified as:

Immediate hypersensitivity

A potential cause of acquired autoimmunity is .

Molecular mimicry

Autoantibodies are probably involved in:

Systemic lupus erythematosus

Which of the following diseases is not due to autoimmunity?

HIV/AIDS