Chapter 16 - Transcription and Translation

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Spliceosomes

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19 Terms

1

Spliceosomes

________ are structures consisting of small nuclear RNAs (snRNAs) and small nuclear ribonucleoproteins (snRNPs) that remove introns from pre- mRNA and then splice together the exons.

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2

genetic information

The process by which ________ in a sequence of DNA nucleotides is transcribed into freshly generated RNA molecules is known as transcription.

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3

reverse transcriptase

Because ________ is less precise than RNA polymerase, retroviruses have a high mutation rate.

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4

phrase central dogma

The ________ refers to the usual flow of genetic information in a cell, in which DNA is transcribed into mRNA, which is subsequently translated into proteins by ribosomes.

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5

peptide bond

Once the ________ between the amino acids is established, the first tRNA releases its amino acid (which is now connected to the second amino acid), and the ribosome releases the first tRNA.

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6

rough endoplasmic reticulum

The information in mRNA is used by ribosomes on the ________ to translate proteins.

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7

TATA boxes

________ are found in most eukaryotic promoters because they are high in thymine and adenine nucleotides.

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8

vesicle

A(n) ________ carrying the protein will bud out from the rough endoplasmic reticulum and go to the Golgi.

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9

tRNA

During translation, ________ (transfer RNA) folds into a three- dimensional structure that functions as an adaptor molecule.

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10

Codons

________ are three base- pair sequences in mRNA that are complementary to the DNA base pair sequence.

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11

DNA

In organisms, ________ and RNA are the bearers of genetic information.

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12

enzyme RNA polymerase

To begin transcription, the ________ must connect to a promoter, which is a noncoding DNA sequence.

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13

MRNA

________ (messenger RNA) is a single- stranded RNA that transports information from the DNA to the ribosome.

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14

three dimensional rRNA functions

The ________ as a ribozyme, catalyzing the translational events.

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15

Introns

________ are non- coding RNA segments found in eukaryotic pre- mRNAs.

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16

Transcription factors

________ are proteins that aid RNA polymerase in binding to the promoter region and initiating transcription.

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17

viral DNA

The information in the ________ incorporated into the host cell's genome will subsequently be transcribed and translated by the host cell.

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18

Reverse transcriptase

________ creates a DNA duplicate of the virus's RNA genome.

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19

DNA

Because the freshly manufactured RNA must be orthogonal to the template ________ strand, RNA polymerase reads the template ________ strand from 3′ to 5′.

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