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84 Terms

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Allele

A variant form of a gene at a particular locus.

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Autosome

A chromosome that is not a sex chromosome.

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Binary Fission

A method of asexual reproduction in single-celled organisms where the cell divides into two identical daughter cells.

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Cell Cycle

The series of events that take place in a cell leading to its division and duplication of its DNA.

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Centimorgan (cM)

A unit used to measure the distance between genes on a chromosome.

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Centromere

The region on a chromosome where sister chromatids are joined.

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Chromatid

One of the two identical halves of a replicated chromosome.

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Chromatin

The complex of DNA and proteins that makes up eukaryotic chromosomes.

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Chromosome

A thread-like structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information.

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Crossing Over (Recombination)

The exchange of genetic material between homologous chromosomes during meiosis I.

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Diploid (2N)

A cell or organism containing two sets of chromosomes.

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DNA

Deoxyribonucleic acid, the molecule that carries genetic information.

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Dominant

An allele that expresses its phenotypic effect even when heterozygous with a recessive allele.

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Epistasis

A circumstance where the expression of one gene is modified by one or more other genes.

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Evolutionary Genetics

The study of the genetic relationships between organisms and the evolution of genes.

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Gamete

A sex cell (e.g., sperm or egg) with a haploid number of chromosomes.

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Gene

A unit of heredity that determines characteristics of offspring.

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Genetics

The study of heredity and the variation of inherited characteristics.

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Genome

All the genetic material in a cell or organism.

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Genotype

The genetic makeup of an organism.

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Haploid (1N)

A cell or organism containing one set of chromosomes.

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Heredity

The passing of characteristics genetically from one generation to another.

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Heritability

The proportion of phenotypic variance attributable to genetic variance.

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Heterozygous

Having two different alleles for a particular gene.

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Homologous Chromosomes

Chromosomes that have the same genes at the same loci but possibly different alleles.

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Homozygous

Having two identical alleles for a particular gene.

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Karyotype

The chromosomal constitution of an individual, typically depicted in an organized manner.

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Linkage

The close location of genes or DNA markers on chromosomes.

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Locus (plural loci)

The specific location of a gene on a chromosome.

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LOD analysis

A statistical technique for determining if two genetic loci are inherited together.

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Meiosis

A type of cell division that produces four daughter cells with half the number of chromosomes.

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Mitosis

A type of cell division resulting in two daughter cells with identical chromosomes.

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Molecular Genetics

The study of the structure and function of genes at the molecular level.

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Phenotype

The observable characteristics of an organism resulting from genotype-environment interaction.

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Ploidy

The number of sets of chromosomes in a cell (e.g., haploid, diploid).

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Probability

The likelihood of a specific event occurring, based on past occurrences.

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Recessive

An allele that expresses its effect only when homozygous.

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Sex Chromosome

A chromosome involved in determining the sex of an organism.

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Sister Chromatids

Two identical copies of a single chromosome connected at the centromere.

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Somatic Cell

Any cell of a living organism other than the reproductive cells.

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Synapsis

The pairing of homologous chromosomes during prophase I of meiosis.

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Transmission Genetics (Mendelian Genetics)

The study of the transmission of traits in successive generations.

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Triploid (3N)

A cell or organism containing three sets of chromosomes.

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Ploidy Level

The number of sets of chromosomes in a cell.

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Mendel's Law of Segregation

States that allele pairs separate during gamete formation; each gamete receives one allele.

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Mendel's Law of Independent Assortment

States that alleles of different genes assort independently during gamete formation.

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Chi-squared Test

A statistical test comparing observed and expected results to determine significance.

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G1 Phase

Cell growth and preparation for DNA replication.

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S Phase

The phase of the cell cycle where DNA replication occurs.

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G2 Phase

Further growth and preparation for cell division in the cell cycle.

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M Phase

The phase of the cell cycle where mitosis and cytokinesis occur.

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Homologous Chromosome Pair

A pair of chromosomes, one from each parent, that carry the same genes.

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S phase of the Cell Cycle

Phase in which DNA is replicated; sister chromatids form.

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Mitosis Purpose

To produce two genetically identical daughter cells for growth and repair.

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Meiosis Purpose

To produce gametes with genetic variation for sexual reproduction.

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Binary Fission vs. Mitosis

Binary fission is simpler, occurring in prokaryotes, while mitosis is more complex, involving a spindle apparatus.

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Meiosis I

The first division in meiosis that separates homologous chromosomes.

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Meiosis II

The second division in meiosis that separates sister chromatids.

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Genetic Variation Importance

Genetic variation is crucial for natural selection and adaptation in populations.

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Recombinant Chromosomes

Chromosomes that result from crossing over during meiosis.

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DNA Replication Mechanism

The process by which DNA is copied during the S phase.

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Phenotypic Ratios

The ratio of different phenotypes in the offspring of a genetic cross.

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Monohybrid Cross Example

A genetic cross between individuals differing in one trait, like flower color.

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Dihybrid Cross Example

A genetic cross involving two traits, such as seed shape and color.

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Trihybrid Cross Example

A genetic cross involving three traits simultaneously.

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Natural Selection Role

Natural selection relies on genetic variation for evolving populations.

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Chromosomal Mapping

The process of determining the position of genes on a chromosome.

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Kinetochores

Protein complexes on chromatids where spindle fibers attach during cell division.

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Germ Cells

Reproductive cells that are haploid and can undergo meiosis.

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Phenotypic Expression

The display of traits resulting from an organism's genotype and environment.

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Gene Mapping

The determination of the order of genes on a chromosome.

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Somatic vs Germ Line Mutations

Somatic mutations occur in non-reproductive cells, while germ line mutations are passed to offspring.

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Environmental Influence on Traits

The impact of external factors on an organism's phenotypes.

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Linkage Mapping

The technique used to find the relative positions of genes on a chromosome.

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Epistatic Interaction

When one gene's expression is influenced by another gene.

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Karyotype Analysis

The examination of an individual's chromosomes to identify chromosomal abnormalities.

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F1 Generation

The first filial generation resulting from a genetic cross.

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Backcross

Crossing an F1 individual with one of its parents.

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Testcross

Crossing an individual with an unknown genotype with a homozygous recessive individual.

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Genetic Drift

Random changes in allele frequencies in a population.

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Speciation

The formation of new and distinct species through evolution.

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Isolation Mechanisms

Processes that prevent interbreeding between different species.

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Chromosomal Abnormalities

Alterations in chromosome number or structure, which can lead to genetic disorders.

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Genetic Counseling Purpose

To provide information and support regarding genetic diseases and conditions.