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Nursing research
Systematic, logical, and empirical inquiry using rigorous methods to produce unbiased, verifiable answers about nursing practice.
Goal of nursing research
To generate new knowledge and add to the nursing profession's evidence base.
Evidence-based practice (EBP)
The integration of best research evidence, clinical expertise, and patient preferences and values to improve patient care.
Impact of nursing research vs. EBP
Research generates new knowledge; EBP applies existing knowledge to practice for better patient outcomes.
Deductive reasoning
A top-down approach that starts with a theory and tests specific hypotheses.
Inductive reasoning
A bottom-up approach that builds general principles or theories from observations.
PICO question
A structured question format guiding research or EBP projects: Population, Intervention, Comparison, Outcome, (Time).
Types of PICO questions
Therapy, Etiology, Diagnosis, Prognosis, Prevention, Meaning.
Sampling
Selecting a portion of a larger population to represent the whole group in a study.
Importance of sampling
It ensures representativeness and allows findings to be generalized to the target population.
Target population
The entire group the study wants to generalize to.
Accessible population
The portion of the target population the researcher can actually reach.
Sample
A subset chosen from the accessible population.
Sampling error
The difference between the sample statistic and the true population parameter.
Factors affecting sampling error
Sample size (larger = less error) and population variability (more variation = more error).
Point estimate
A single best estimate of a population value.
Interval estimate (confidence interval)
A range in which the true population value likely falls.
Narrow confidence interval
More precision and less variability.
Wide confidence interval
Less precision and greater variability.
Data collection methods
Biophysiological measures, records/data mining, structured observation, and surveys/self-reports.
Reliability
The consistency of measurement results over time, raters, or items.
Validity
The degree to which an instrument measures what it intends to measure.
Types of validity
Content validity, criterion validity, and construct validity.
Relationship between reliability and validity
A tool can be reliable without being valid, but it cannot be valid if it is not reliable.
Quantitative research
Research using numerical data to test relationships, effects, or cause-effect hypotheses.
Qualitative research
Research exploring experiences, meanings, and perceptions using words and observations.
Hierarchy of evidence
Meta-analysis, systematic review, randomized controlled trial, quasi-experimental, cohort, case-control, cross-sectional, case report, expert opinion.
Properties of a true experimental design
Randomization, manipulation, and control.
Blinding
Concealing group assignments to reduce bias (single-, double-, or triple-blind).
Allocation concealment
Preventing knowledge of upcoming group assignments before enrollment.
Intervention fidelity
Ensuring the intervention is delivered consistently as planned.
Intention-to-treat analysis
Analyzing participants in their original assigned groups regardless of completion or adherence.
Independent variable
The variable manipulated by the researcher (the cause).
Dependent variable
The variable that measures the outcome (the effect).
Quasi-experimental design
It lacks random assignment but includes an intervention.
Confounding
When a third variable affects both the independent and dependent variables.
Bias
A systematic deviation from truth that distorts study results.
Strengths of quasi-experimental designs
Practical, ethical, and adaptable to real-world settings.
Weaknesses of quasi-experimental designs
Less control and higher risk of confounding and bias.
Observational design
A study where the researcher observes without manipulating variables.
Difference between observational and experimental design
No manipulation or randomization; focuses on associations, not causation.
Main types of observational studies
Cohort, case-control, and cross-sectional.
Cohort study
Measures exposure before outcome to assess incidence or risk (prospective or retrospective).
Case-control study
Identifies past exposures after outcome occurrence to find risk factors (retrospective).
Cross-sectional study
Examines exposure and outcome at the same time to measure prevalence.
Internal validity
The degree to which observed changes in the DV are truly caused by the IV.
External validity
The generalizability of results to other populations or settings.
Systematic review
A comprehensive synthesis of all available studies on a specific research question using rigorous, transparent methods.
Meta-analysis
A statistical method that combines quantitative results from multiple studies to produce a single overall effect.
Forest plot interpretation
If the diamond crosses the line of no effect, results are not significant; if it doesn't, they are statistically significant.
Levels of measurement
Nominal, ordinal, interval, and ratio.
Confidence interval
A range that likely contains the true population value (commonly 95% CI).
Type I error
Rejecting a true null hypothesis (false positive).
Type II error
Failing to reject a false null hypothesis (false negative).
Alpha level for Type I error
Typically 0.05 (5%).
Statistical significance
Indicates that results are unlikely due to chance (p < 0.05).
Clinical significance
Indicates whether results have real-world, meaningful impact.
Power in inferential statistics
The probability of detecting a true effect (1 - β), ideally ≥ 0.80.
Emergent design
A flexible research plan that evolves as data collection continues.
Reflexivity
Researcher self-awareness of bias and influence on interpretation.
Purposive sampling
Selecting participants who best represent or inform the phenomenon of interest.
Data saturation
The point at which no new data or themes emerge.
Triangulation
Using multiple sources, methods, or researchers to verify results.
Memoing
Writing notes to capture analytical insights during data analysis.
Bracketing
Setting aside researcher preconceptions to prevent bias.
Coding
Organizing data into categories or themes for analysis.
Phenomenology
Explores the essence of lived experiences among several individuals.
Grounded theory
Generates a theory from data collected in the field about a process or interaction.
Ethnography
Describes and interprets shared cultural patterns in a group.
Narrative study
Explores and retells stories of individual experiences.
Case study
Provides an in-depth description and analysis of a specific case or situation.
Trustworthiness criteria in qualitative research
Credibility, transferability, dependability, confirmability.