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Define Anatomy
the scientific discipline that investigates the body's structures
Define Developmental Anatomy
studies the structural changes that occur between conception and adulthood
Define Embryology
subspecialty of developmental anatomy, studies changes from conception to the end of the 8th week of development
Define Cytology
examines the structural features of cells
Define Histology
examines tissues, which are composed of cells and the materials surrounding them
Define Gross Anatomy
the study of structures that can be examined without the aid of a microscope
How is the body studied in regional anatomy?
area by area
Define System
a group of structures that have one or more common function
Define Surface Anatomy
involves looking at the exterior of the body to visualize structures deeper inside the body
Who was the first medical scientist to use x-rays?
Wilhelm Roentgen
Define Physiology
the scientific investigation of the processes or functions of living things
What are the major goals of studying human physiology?
to understand and predict the body's responses to stimuli and to understand how the body maintains conditions within a narrow range of values in a constantly changing environment
Define Cell Physiology
examines the processes occurring in cells
Define Systemic Physiology
considers the functions of organ systems
Define Pathology
the medical science dealing with all aspects of disease with an emphasis on the cause and development of abnormal conditions as well as the structural and functional changes resulting from disease
Name the six levels at which the body can be studied
chemical, cell, tissue, organ, organ system, organism
Define Organization
refers to the specific interrelationships among the parts of an organism
Define Metabolism
all of the chemical reactions taking place in the cells and internal environment of an organism
Define Responsiveness
an organism's ability to sense changes in its internal or external environment
Define Differentiation
involves changes in a cell's structure and function from an immature, generalized state to a mature, specialized state
Define Morphogenesis
the change in the shape of tissues, organs, and the entire organism
Define Reproduction
the formation of new cells or new organisms
Who is considered the first modern anatomist?
Andreas Vesalius
Define Homeostasis
the existence and maintenance of a relatively constant environment within the body
Give two examples of homeostatic mechanisms
sweating and shivering
Define Negative-Feedback
the response to the original stimulus results in deflation from the set point, becoming smaller
What are the three components of a negative feedback mechanism?
receptor, control center, effector
What is the function of a receptor?
monitors the value of a variable
What is the function of the control center?
establishes the set point around which the variable is maintained through communication with the receptors and effectors
What is the function of an effector?
adjusts the value of the variable back toward the set point
Define Positive-Feedback
response to the original stimulus results in deviation from the set point becoming even greater
What are the two basic principles of positive feedback?
1. many disease states result from failure of negative feedback systems to maintain homeostasis
2. some positive feedback systems can be detrimental instead of helpful
What are the organs of the integumentary system?
skin and accessory structures such as hair, glands, and nails
What are the functions of the integumentary system?
protection, sensation, temperature regulation, vitamin D production, excretion
What is the Epidermis?
the superficial layer of skin made of stratified squamous epithelial tissue
T/F:
The epidermis is highly vascular
false
What is the function of keratinocytes?
produce the protein keratin to make cells more durable
What is the function of melanocytes?
produce the pigment melanin
Langerhans cells
part of the immune system
merkel cells
associated with nerve endings, responsible for detecting light touch and superficial pressure
What are the layers of the epidermis from superficial to deep?
stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
Stratum basale
deepest portion of epidermis, made of cuboidal/columnar cells
stratum spinosum
8-10 layers of flattened, diamond-shaped cells
stratum lucidum
thin, clear zone above stratum granulosum made of dead cells with indistinct boundaries
stratum corneum
25+ layers of overlapping squamous cells
cornfield cells
dead cells with hard protein envelope and filled with keratin
thick skin
has all 5 strata and the stratum corneum has many layers
where is thick skin found?
found in areas subject to lots of pressure and friction, hairless
thin skin
more flexible than thick skin, covers the rest of the body, strata are thinner, has hair
dermis
connective tissues
what cells are in the dermis?
fibroblasts, adipocytes, and macrophages
T/F:
The dermis contains mostly collagen fibers, but some elastic and reticular fibers
true
T/F:
the dermis is avasuclar
false
Papillary layer
loose connective tissue with thin fibers, give us fingerprints
reticular layer
dense irregular connective tissue, main layer of dermis, elastic and collagen fibers create cleavage lines
subcutaneous tissue
attaches skin to underlying bone and muscle, supplies skin with blood vessels and nerves, stores lipids
What is the subcutaneous tissue made of
loose connective tissue with collagen and elastic fibers
Hair shaft
protrudes above the surface of the skin
Hair root
located below the surface of the skin, base expands to form the hair bulb
What are the 3 concentric layers of dead keratinized epithelial cells?
medulla, cortex, cuticle
hair medulla
central axis of the hair
hair cortex
surrounds medulla and forms the bulk of the hair
hair cuticle
single layer of cells containing hard keratin
hair follicle
tubelike invagination of epidermis that extends into the dermis, where the hair develops and grows
dermal root sheath
dermis that surrounds epithelial root sheath
function of the epithelial root sheath
holds hair in place
growth stage of hair
hair increases in length as new matrix cells are produced
resting stage of hair
no hair growth

arrector pilli
muscle that pulls hair follicle into upright position
sebaceous glands
alveolar glands that produce sebum along with the holocrine glands
what are the two types of sweat glands
eccrine and apocrine
eccrine glands
regulate body temperature, most common type of sweat gland, merocrine glands
(dermis)
apocrine glands
cause of body oder, open into hair follicles, found in axillae and genitalia and around the anus, become active at puberty
ceruminous glands
modified eccrine glands in the ear canal, release cerumin
mammary glands
modified apocrine glands in the breasts that produce milk
___________ nail root and _________ nail body
proximal, distal
T/F:
The nail fold covers lateral edges
true
T/F:
nail grove holds the middle of the nail in place
false
Cuticle
part of skin that grows onto nail body

hyponychium
portion of stratum corneum under free edge of nail body
function of the nail matrix
forms nail root
nail bed
attaches to nail; between nail matrix and hyponychium
lunula
portion of nail bed that appears whitish
what is a burn?
injury to a tissue cause by heat, cold, friction, chemicals, electricity, or radiation
partial-thickness burns are classified as
first and second degree burns
first degree burn
involve only epidermis and may result in redness, pain, and slight swelling
second degree burn
damage epidermis and dermis
full thickness burns
third degree burns
third degree burn
epidermis and dermis are completely destroyed along with sensory receptors and deeper tissue may be involved; painless
What are the four major parts of the skeletal system?
bones, cartilage, tendons, ligaments
What are the functions of the skeletal system?
body support, organ protection, body movement, mineral storage, blood cell production
What are the three types of cartilage?
hyaline cartilage, fibrocartilage, elastic cartilage
chondroblasts
produce a matrix surrounding themselves
chondrocyte
a chondroblast surrounded by the matrix, occupies a lacuna
perichondrium
protective connective tissue sheath
articular cartilage
hyaline cartilage that covers the ends of bones where they come together to form joints, has no perichondrium, blood vessels, or nerves
two types of cartilage growth
appositional and interstitial
appositional growth
chondroblasts in the perichondrium add new cartilage to the outside edge of the existing cartilage
interstitial growth
chondrocytes in the center of the tissue divide and add more matrix between the existing cells
three types of bone cells
osteoblasts, osteocytes, osteoclasts