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NURS207: Foundations
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body fluid is primarily made up of…
water
what percent of the body is water?
70%
obese people have ____ water percentage
less
water is ___ free
fat
____ tend to have a higher percentage of body fat than men
women
purpose of water in the body
solvent for electrolytes, maintains normal body temp, transportation of nutrients, wastes, hormones, RBC & WBC, platelets
intracellular fluid
65% of liquid, fluid found within the cells of the body
extracellular fluids
36% of fluid, fluid outside the cells
intracellular fluid contains solutes such as…
oxygen, electrolytes, glucose
intracellular fluid is vital to normal cell functioning because..
it provides a medium for pmetabolic processes to take place
extracellular fluid is the transport system that…
carries nutrients to the cells and waste products from the cellse
extracellular fluid consists of…(3 kinds of fluids)
interstitial, intravascular, transcellular
transcellular fluid is within…
the cerebrospinal column, joints, eyes, lymph, pleural cavity
electrolytes
contain electrically charged particles called ions
cations
ions with a positive charge
anions
ions with a negative charge
examples of cations
sodium, potassium, calcium, magnesium
examples of anions
chloride, bicarbonate, phosphate, sulfate
cations of the intracellular fluid
potassium (K+) and Mg (magnesium)
anions of intracellular fluid
phosphate (PO4-) and sulfate (SO4)
ions of extracellular fluid
calcium (Ca++) and sodium (Na++)
albumin
protein in the plasma, carries ions, has an osmotic effect, draws water to it
osmolality
the concentration of solutes to water
when body water decreases…
the concentration of solutes increases, serum osmolality increases
urine osmolality measures..
renal function and hydration status
acid
a substance containing hydrogen ions that can be released
base
a substance that accepts hydrogen ions
pH
the hydrogen ion concentration
normal pH
7.35-7.45
acidosis range
6.8-7.35
alkalosis
7.45-7.8
chemical buffers
prevent body fluids from becoming too acidic or alkaline
what is the most common body acid?
carbonic-acid (H2CO3)
what is the most common body base?
bicarbonate (HCO3-)
what should the ratio of bicarbonate to carbonic-acid be?
20:1
when serum CO2 is increased, in causes…
respirations to increase in rate and depth
when serum CO2 is decreased, it causes respirations to ___ in rate and depth
decrease
if there is acidosis the kidneys…
excrete hydrogen ions and form bicarbonate ions
if there is alkalosis the kidneys…
retain hydrogen and excrete bicarbonate (HCO3-) ions
what electrolytes need to be taken daily because they are not in the body?
sodium and chloride
what electrolytes are stored in the cells and bones?
potassium and calcium
osmotic pressure…
holds fluid in the vessels
hydrostatic pressure…
forces fluid into the tissue spaces
solute
the substance that dissolves in a solution
solvent
the liquid/solution
osmosis (passive)
the movement of a pure solvent through a semipermeable membrane from an area of less concentration to higher concentration until equilibrium is reached
osmotic pressure
the drawing power for water
a high solute concentration means…
a high osmotic pressure and it draws water into itself until equilibrium is reached
osmolarity of a solution is the…
concentration of particles in a solution (solute), pulling power of the solution
diffusion
the movement of a solute in a solvent across a semipermeable membrane from an area of high concentration to an area of low concentration
osmosis refers to ____ movement
solvent
diffusion of solutes refers to ____ solute movement
solute
net movement
movement that occurs between diffusion and osmosis until equilibrium is reached
capillary filtration
process by which water and diffusible substances move together in response to pressure of blood against the walls of the capillaries
what is the movement during capillary filtration? (high to low or low to high)
high to low pressure, this is how nutrients and oxygen are delivered to tissues and it is driven by hydrostatic pressure
hydrostatic pressure
the pressure of fluid on the walls of the container it is contained
reabsorption
prevents too much fluid from leaving capillaries no matter how much hydrostatic pressure exits
osmotic pressure is affected by ____ especially ____
plasma proteins such as albumin
colloid osmotic pressure
tends to keep fluid in the intravascular which opposes hydrostatic pressure
at the _____ end of the capillaries, hydrostatic pressure is greater than colloid pressure which causes fluid and solute to move out of the capillary and into the interstitial space
arterial
at the _____ end of the capillaries, colloid pressure is greater than hydrostatic pressure so the colloid pressure draws water back into capillaries to be filtered through the kidneys
venous
active transport
goes against the concentration gradient, requires metabolic activity and energy
how do sodium and potassium move in and out of the cell? (by what kind of transport)
active transport
fluid in the body can regulated by…
fluid intake, output, hormonal controls
fluid intake daily
oral is 1500 mL but with foods it will equal 2500 mL
thirst is stimulated by…
receptors in the hypothalamus, eating salty food or excessive fluid loss
thirst is dimisnihed by…
illness, LOC, aging
decreased thirst may be due to…
hypovolemia
fluid output daily
1500 mL through urine
sensible water loss
can be measured through urination, defecation, wounds
insensible water loss
cannot be measured, evaporation through skin and lungs
the kidneys must produce a minimum of ____ mL of urine every 24 hrs
500-600
the kidneys must produce at least ____ mL/hr
30
urine production is influenced by what two hormones?
ADH/vasopressin and aldosterone
Which of the following is true?
Hydrostatic pressure is greatest at the venous end of the vessels.
Osmosis refers to the movement of solvent (water) in the direction of the greatest concentration of solutes.
Ideally, intake and output should be equal.
ADH causes diuresis.
Osmosis refers to the movement of solvent (water) in the direction of the greatest concentration of solutes.
Ideally, intake and output should be equal.
relative changes of fluid and electrolyte imbalance
when fluids or electrolytes shift from one body space to another
absolute changes of fluid and electrolyte imbalance
when fluids and electrolytes are lost outside the body
hypovolemia occurs when…
the body loses both water and electrolytes from the ECF
dehydration
results from loss of water from circulation, fluid shifts from inside the cell to the outside
hemoconcentration
where there is an increased concentration of cells and solids in the blood due to fluid loss
causes of dehydration or hypovolemia
diabetes, renal failure, fever, exercise, sweating, vomiting, diarrhea
assessments of hypovolemia or dehydration
dry mucous membranes, decreased tissue turgor, tachycardia, tachypnea, low BP, flat neck veins, thirst
interventions for hypovolemia and dehydration
give oral fluids and IVs, mouth care, stop bleeding and replace blood
hypervolemia
the body retains water and sodium
edema
excess interstitial fluid
what is edema caused by?
increased capillary permeability, increased capillary hydrostatic pressure, decreased plasma oncrotic pressure
third space syndrome
fluid shifts from the vascular space into an area that is not readily accessible
water intoxication
overhydration, body takes in more water than it excretes
water intoxication symptoms
mental changes, blurred vision, muscle cramps and twitching, paralysis, N/V