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Flashcards on Energy Metabolism
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Energy Metabolism
All chemical reactions by which the body obtains and spends energy.
Anabolic process
Building of substances.
Catabolic process
Breakdown of substances.
Oxidation
Losing electrons.
Reduction
Gaining electrons.
Oxidation in cellular metabolism
Results in ATP formation (energy currency).
Metabolic coupling
One metabolic reaction cannot proceed without the reactions it is linked to.
1st law of thermodynamics
Energy cannot be created nor destroyed; in a closed system, energy is constant, but can be transformed.
Steady state
Energy intake = Energy Expenditure (and Energy storage).
Positive energy balance
More energy coming into the body than needed, stored as adipose tissue.
Negative energy balance
Extra energy comes from storage.
1g of carbohydrate
4 kcal or 17 kj.
1g fat
9 kcal = 38kj.
1g protein
4 kcal = 17 kj.
1g alcohol
7 kcal = 30kg.
Calorimetry
The science of measuring heat production.
Indirect calorimetry
Measure of O2 consumption and CO2 production as an indicator of heat production.
Respiratory Quotient (RQ)
Ratio of moles CO2 produced per moles O2 consumed at the tissue level.
2nd law of thermodynamics
Chemical transformations always result in a loss of free energy available to drive metabolic process.
Gibbs Free energy (G)
Free energy available to drive metabolic processes.
Metabolic rate
Measure energy balance.
Resting metabolic rate
Estimate of energy required while at rest.
Basal Metabolic rate
Clinical measurement of metabolism, measured under several standardized conditions.
ATP
Adenosine Triphosphate.
Glycolysis
Breaking glucose down to pyruvic acid.
Glycogenesis
Taking glucose and forming glycogen.
Glycogenolysis
Break down of glycogen to glucose.
Gluconeogenesis
Creation of new glucose.
Beta Oxidation
loss of electrons.
Lipolysis
Taking triglyceride and breaking it down to fatty acids and glycerol.
Lipogenesis
Building up.
Liver
Important supplier.
Muscle
Tends to be a consumer.
Red blood cells
Only use anaerobic glycolysis.