Y2 Pharmaceutical calculations

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4 Terms

1
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What is the equation for bioavailability?

Bioavailability = Drug in circulation / Dose

<p>Bioavailability = Drug in circulation / Dose</p>
2
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What is the equation for loading dose required?

Vd = Volume of distribution

Css = Required concentration at steady state

Determined from reference sources

F = Drug bioavailability

<p>Vd = Volume of distribution</p><p>Css = Required concentration at steady state</p><p>Determined from reference sources</p><p>F = Drug bioavailability</p>
3
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What is the equation for volume of distribution?

VD is in Litres (L)

<p>VD is in Litres (L)</p>
4
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What is the equation for maintenance dose?

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