Chapter 12: The Gastrointestinal system and Drug Therapy

What is another term for heartburn?

Gastroesophageal Reflux Disease (GERD)

Which drug listed below is an example of an OTC drug used to treat GERD?

cimetidine

Which histamine H2-receptor antagonist affects the cytochrome P-450 system and may interact with many other drugs?

cimetidine

Which drug listed below forms a protective coat over an ulcer, helping it resist degradation by gastric acid, pepsin, and bile salts?

sucralfate

What GI disorder is characterized by inflammation of the large intestine or colon that leads to diarrhea, abdominal pain, and weight loss?

ulcerative colitis

Which drug or drug combination is correctly paired with its DEA control schedule?

dphenoxylate/atropine C-V

Which medication below treats diarrhea by interfering with enzyme-dependent electron transfer in anaerobic energy metabolism?

nitazoxanide

What is a potential problem associated with low-fiber diets?

constipation

Which drug listed below is a stimulant laxative?

bisacodyl

Which drug below is approved for chronic idiopathic constipation?

lubiprostone

Which of the following drugs is used for chemotherapy-induced emesis and frequently causes headaches in patients treated with it?

ondansetron

Which of the following must be dosed hourly to treat GERD?

antacids

What drug used to treat GERD is not a proton pump inhibitor?

famotidine

What is peptic disease?

a disorder of the upper GI tract caused by the action of acid and pepsin

Patients in the intensive care unit are frequently given H2 blockers to prevent the development of

stress ulcers

Antimotility medications are used to treat

diarrhea

What drug is used to treat traveler's diarrhea?

rifaximin

Patients on long-term narcotic pain medication should also be taking a(n)

stimulant laxative

Psyllium (Fiberall, Metamucil) is used as each of the following except as a(n)

antiemetic agent

The sensation of the room spinning when one gets up or changes positions is known as

vertigo

What is the goal of antiemetics?

to reduce nausea and vomiting

Hepatitis is not caused by

bacterial infections

Which of the following drugs is a synthetic prostaglandin analog for NSAID-induced gastric ulcers that is also used to induce labor?

misoprostol

Which of the following PPIs is available as a tablet that is placed on the tongue and allowed to dissolve (i.e., an orally disintegrating tablet)?

lansoprazole

Which of the following PPIs has an injectable dosage form?

pantoprazole

A patient who has an aspirin sensitivity should not take which of the following medications?

bismuth sibsalicylate

Which of the following conditions is an autoimmune disease?

Crohn's

Which of the following drugs is not typically associated with constipation?

magnesium

Which of the following is used to treat flatulence and is an inert silicone polymer for gastric defoaming?

simethicone

Which of the following drug classes is used to treat HIV and hepatitis B infections?

nucleoside reversw transcriptase inhibitor