virus meds

what are the five meds for viruses

acyclovir

ganciclovir

rivavirin

lamivudine

zidovudine

what is acyclovir used for

HSV

VZV- varicella

prophylaxis

CMV

What is acyclovir action

interferes with viral DNA synthesis

adverse effects of acyclovir

malaise

headache

NV

contraindication with acyclovir

HF

kidney disease

pregnancy

IV admin for acyclovir

slowly over an hour to risk neurotoxicity - monitor neurological checks

drug interactions with acyclovir

nephrotxic meds

what is Ganciclovir used for

treat CMV

Action of Ganciclovir

inhibits DNA synthesis

adverse effects of Ganciclovir

chills

fever

pruritic (itchy)

anorexia

Leukopenia, neutropenia, thrombocytopenia

neuropathy

sepsis

hematuria

infertility issues

teratogenic- cause fetal demise

black box warning for Ganciclovir

carcinogenic and teratogenic

thrombocytopenia

granulocytopenia

cancer causing