Exotics

African hedgehog

Toxic neutrophil

Mouse and rat, what cell type?

Eosinophil

Mouse

Monocyte

Guinea pig

Monocytes

Guinea pig

Large granular lymphocyte

Guinea pig

Lymphocyte with Kurloff body

Chinchilla

Heterophil

Rabbit

Heterophil

Rabbit

Basophil

Rabbit

Eosinophil arrow, heterophil below

Rabbit

Heterophil and lymphocyte

Rabbit

Monocyte

Ferret

Eosinophil and neutrophils

Hedgehog

Neutrophil and eosinophils

Hedgehog

Neutrophils and monocytes

Guinea pig bone marrow, identify each

Rubriblast, prorubricyte, rubricyte and band

Guinea pig bone marrow

Myeloblast

Guinea pig bone marrow

Promyelocytes

Guinea pig bone marrow

Basophil myelocyte

Guinea pig bone marrow

Promegakaryocyte next to megakaryocyte

Guinea pig bone marrow

Promegakaryocyte

Chinchilla

Toxic seg and band

Chinchilla

Toxic band

What infectious agent causes diarrhea in ferrets, often with green mucus, and in chronic conditions a bird-seed-like appearance?

Two main ddx?

Ferret enteric coronavirus (epizootic catarrhal enteritis, ECE)

Ddx: foreign body and Helicobacter mustelae gastritis

Cytospin from tracheal wash of a guinea pig

Normal. Ciliated respiratory epithelial cells (CRE), goblet cells (G), heterophil (H), macrophage (M)

Conjunctival scraping from a guinea pig

Normal melanocytes

Choroid plexus imprint (from CNS)

Alpha cells have dark blue cytoplasm and densely stained nuclei, and beta cells have paler nuclei with a cribriform chromatin distribution. Two gamma cells with intracellular vesicles are seen (arrows).

Guinea pig conjunctival scraping

Normal epithelium

Ferret lymph node

Normal, two mast cells in centre

Ferret, liver

Intracytoplasmic bile pigment

Rabbit, nasal flush

Heterophilic rhinitis

Ferret, subcutaneous mass

Mixed-cell inflammation

Mass from a hamster

Fibroblasts from an abscess

Ferret abdominal fluid

Macrophagic inflammation in peritonitis

Hedgehog, skin

Eosinophilic inflammation

Tiger, tongue

Neutrophils, eosinophils, and a mast cell

Sugar glider, skin

Calcinosis circumscripta

Ferret, liver

Macrophagic inflammation with Mycobacterium (goodii)

Rabbit, conjunctival swab

Heterophilic inflammation

Rat, skin

Lipoma

Ferret, skin

Histiocytoma

Ferret, chordoma

Ferret, tail

Chordoma

Large foamy physaliphorous cells with a background of mucinous pinkish material

Ferret, tail

Chordoma

Large foamy physaliphorous cells with a background of mucinous pinkish material

Rat, ear

Zymbal gland adenoma

Rat, ear

Zymbal gland adenoma

Caudal abdominal mass in a hedgehog

Uterine leiomyoma

Ferret, prostate

Squamous metaplasia

Ferret, lymph node

Reactive

Ferret, spleen

Multiple myeloma

Guinea pig, neck mass

Thyroid adenoma

Tiger, skin

MCT

Rat

Histiocytic sarcoma

Ferret, lymph node

Lymphoma

Ferret, lymph node

Lymphoma

Ferret, abdominal mass

T-cell lymphoma with pleomorphism

Ferret, spleen

Multiple myeloma

Ferret

Carcinoma

Guinea pig, uterine impression

Endometrial adenoma

Hamster, ventral skin

Mammary adenocarcinoma

Ferret, abdominal mass

Adrenal adenocarcinoma

Ferret, abdominal mass

Adrenal adenocarcinoma

Hedgehog, oral FNA

SCC

Gerbil, abdominal mass

Poorly-differentiated sarcoma

Rabbit, nodule on muzzle

Shope fibroma

Rabbit (Shope) fibroma virus (Poxviridae)

The virus ordinarily produces localized fibromas where cytologic preparations consist of spindle-shaped cells exhibiting moderate anisocytosis and anisokaryosis (Figures  7.86a and  7.86b). The nuclei are large (1–3 times the size of erythrocytes), round to oval, eccentric, and exhibit finely stippled chromatin with multiple nucleoli. The basophilic cytoplasm occasionally contains round to oval eosinophilic inclusions that vary in size (3–5 μm) and shape

Sugar glider, mass projecting from right aspect of marsupium

Carcinoma or ACA, ddx amelanotic melanoma

Ferret, perianal mass

Anal sac adenocarcinoma

Guinea pig, skin

Melanoma

Ferret, abdominal mass

Ferret, abdominal mass

Term

Adrenal gland adenoma

Hedgehog, right cervical mass

Thyroid carcinoma

Ferret, abdominal fluid cytospin

Chylous effusion, but see mixed population of nondegenerate neutrophils and macrophages that show intermittent foamy cytoplasm. Small lymphocytes are in low numbers.

Ferret, abdominal mass

Lymphoma

Ferret, fluctuant mass on the head

Mucocele

Hamster, fecal smear

Campylobacter-like organisms in case of septic colitis

Hamster, rectal swab

Campylobacter-like organisms in a case with colitis

Hamster, fecal smear

Budding yeast in a case with diarrhea

Ferret, lung

Blastomyces dermatitidis

Rabbit, fecal smear

Saccharomyces spp. yeast, part of normal flora of the cecum

Rabbit, fecal smear

Saccharomyces spp. yeast, part of normal flora of the cecum

Rat, fecal smear

Trichomonas in a case with diarrhea

Hedgehog, swelling under right forelimb

Mammary adenocarcinoma

Rat, rapidly growing mass on face

Ddx sebaceous carcinoma, Zymbal gland adenocarcinoma based on location

Hedgehog, vaginal mass

Leiomyosarcoma, was also within the uterine horn

Sugar glider, mass in left axilla

Calcinosis circumscripta

Blood smear from a turkey

Clumping, vacuolation, and pyknotic nuclei from 48h in EDTA

Avian blood smears

Clumping due to heparin

Blood smear from eclectus parrot

Hypochromic RBCs

Blood smear from a turkey vulture

Increased numbers of immature erythrocytes (early and mid-polychromatic rubricytes) without an appropriate increase in polychromasia due to lead poisoning

Avian blood smear

Artifact from slow drying

Blood smear from an eclectus parrot

Agglutination and erythrophagia

Blood smear from a hawk

Basophilic rubricyte and increased polychromatophils

Amazon parrot blood

Lymphocyte

Conure blood

Immature erythrocyte—early polychromatic rubricyte (arrow), lymphocyte (arrowhead), and thrombocytes

Domestic chicken blood

Large lymphocytes (arrowheads), medium lymphocyte (arrow), and thrombocyte

Amazon parrot

Lymphocytes

Barred owl

Lymphocyte with azurophilic cytoplasmic granules (arrow) and thrombocyte

Domestic duck

Two large lymphocytes (center) and two thrombocytes (arrow)

Conure

Large reactive lymphocyte

Gannet (a sea bird) blood smear

Monocytosis