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what is a CPG
comprehensive and current summary of evidence, expertise, and patient perspective regarding a condition
what is the purpose of a CPG
make recommendations about best clinical practice for a specific condition
CPGs are ____ not ______
guidance, standard of care
what are the 5 steps in CPG development?
1) determine a specific, focused topic requiring interview
2) identify and convene relevant stakeholders
3) conduct a systematic review
4) develop recommendations
5) submit for external review
what are 6 unique characteristics of CPGs
interdisciplinary, sponsored, kept current, documented consensus, recommendations, long length
clinicians should use CPGs to
make informed decisions
what 3 things should you consider when using a CPG?
year published, sponsorship, breadth of authorship
a primary difference in purpose between a SRMA and a CPG is:
SRMAs are more objective data findings while CPGs are more subjective recommendations based on data
what does an event represent
an outcome
an event is typically:
dichotomous, defined by a standard
what is event rate
how many people experienced or did not experience the event
what is required to calculate the event rate?
counts (numerical values)
how do you calculate experimental event rate (EER)?
treatment event yes/total in treatment group
how do you calculate control event rate? (CER)
control event yes/total in control group
where might you find the counts you need to calculate event rate?
tables, figures, text
what is the equation for relative risk/benefit?
EER/CER
what does relative risk/benefit mean
if you are in the treatment group, you are X times more/less likely to experience the event than the control group
what is absolute benefit increase/risk reduction (ABI or ARR)?
the actual difference in risk/benefit between treatment and control groups
how do you calculate ABI / ARR
EER-CER
what is number needed to treat (NNT)
reflects the number of patients needed to treat for at least 1 person to experience the benefit/avoid the risk
what would a perfect NNT be
1
how do you calculate NNT
1/ABI
in which equation should you use the aboslute value?
NNT
what is peer review?
the study has been double-checked by peer experts for quality, interpretation, etc.
what presentation venue is not necessarily presenting peer reviewed publications?
institutional
what are the 3 possibly outcomes after submission for publication?
rejection, revise/resubmit, acceptance
what are the quality standards used in peer-reviewing?
subjective to each reviewer
true or false: there is no checklist/guideline for peer-reviewers to follow when reviewing potential publications
true
true or false: peer review is exempt from bias due to rigorous screening procedures
false
true or false: if you are in the lab for some research, you get to be an author on the study
false
what is impact factor?
the ratio of citations of a journal in a year to number of articles published in the journal in the past 2 years
a key indicator of the quality of a journal is:
impact factor
what are 2 measures of a journal’s strength
impact factor and ranking by discipline
what should you consider when choosing a journal to submit your research to?
aims and scope, accessibility, and strength of the journal
what is H-index
the number of published manuscripts (H) that has the same number of citations (H)
H-index is like ___ ___ but for author strength
impact factor
the higher the H-factor, the more articles that have been ____ AND ____
published, referenced
what are the 4 steps in reviewer participation
commit to the process, offer constructive assistance to authors, recommend a decision/provide your rationale, be prepared to review a revised version
where might you find predatory journals?
open access publishing
what is a hallmark of predatory publishers?
reaching out to authors unsolicited asking for content