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Mouthwash
are adjunct to, not a substitute for, regular brushing and flossing
Plaque
primary aetiologic agent int he development of dental caries, gingivitis, and, periodontal disease
mechanical removal of plaque
_____________ through frequent and efficacious brushing and flossing is the principle means of preventing periodontal disease and diminishing the risk of caries
Mouthwashing
easier to perform and may aid in controlling supragingiva plaque and gingivitis
short periods of time
Mouthwashes should only be used for ______ and should never be the sole means of oral hygiene
Chlorhexidine gluconate
is a cationic bis-guanide with broad spectrum antimicrobial activity
Chlorhexidine gluconate
currently the most effective mouthwash for reducing plaque and gingivitis
Chlorhexidine
may also potentiate oral discomfort in patients with chemo-therapy induced mucositis, xerostomia, or ulcerative oral mucosal conditions
Benzydamine hydrochloride
added to some chlorhexidine containing mouthwashes for its AAA and anesthetic properties,
thymol
eucalyptol
menthol
methyl salicylate
4 phenol related essential oils that claim to penetrate the plaque biofilm and kill microorganisms that cause gingivitis.
phenol related essential oils
MOA involve bacterial cell destruction, enzyme inhibition, and extraction of endotoxin from gram negative bacterial
Cetylpyridinium chloride
quaternary ammonium compound with antiseptic and antimicrobial properties
Cetylpyridinium chloride
it is cationic and thus binds to bacterial surfaces causing disruption of cell membranes, leakage of intracellular components and disruption of metabolism.
Sodium benzoate
if active ingredient, acts by dispersing fatty proteinacious substances
Triclosan
increase ability of mouthwash
Hydrogen peroxide
has been used as treatment for minor gingivitis for its oxidizing cleansing properties
Hydrogen peroxide
a bleaching agent used for its oxidative properties
Hydrogen peroxide
recommended for the treatment of acute ulcerative disease
Hydrogen peroxide
Used for stain removal
Povidone iodone
an iodophore which iodine is linked to povidone.
Povidone iodine
display affinity for the cell membrane thereby delivering free iodine directly to the bacterial cell
Povidone iodine
broad spectrum of activity against bacteria, fungi, protozoa, and viruses
Metabolic complications
absorption of excess iodine has been postulated to result in ____
lysozyme
lactoferrin
glucose oxidase
lactoperoxidase
mouthwashes that are directed against the bacterial peroxidase system contain 4 enzymes namely:
Fluoride
assists in the prevention of dental caries by promoting remineralization of fluorapatite and fluorohydroxyapatite thereby increasing enamel resistance to acid attack
Fluoride
available in different concentrations as acidulated phosphate fluoride or sodium fluoride