Med Pharm 1

What 4 classes is epi

Sympoathomimetic

Vasopressor

inotrope

What is the MOA for epi

Stimulates beta and alpha receptors

beta more than alpha

What is the concentration and dose for IM epi for anaphylaxis

1g/1mL

0.3-0.5

What is the duration of IM Epi

5-15 minutes

What is the RPT time and dose for IM epi anaphylaxis

0.3-0.5mg q5-15 minutes

or start drip

What are 2 indications for respiratory epi

bronchodilator

croupe

What is 2 routes and dosages for respiratory epi

0.3-0.5mg IM

0.5mg Neb in 3mL of saline over 15 minutes

What is the RPT dosage and time for respiratory IM epi

q20min x3

What is the repeat time and dosage for neb respiratory epi

q2hr

0.5mg in 3mL NS over 15 minutes

What is the pediatric dosage for IM epi and max dosage

0.01mg/kg

0.3mg MAX

What is the pediatric dosage for neb epi

0.05mg/kg in 3mL NS over 15 minutes

What are the indications for vasopressor epi drip

hypotension

unstable bradycardia

What is the concentration for vasopressor epi drip vial

1mg/10mL

What is the dosage for vasopressor epi drip

2-20mcg/min IV/IO

How do you set up the fluid bag for a vasopressor epi drip (concentration, amount in bag, volume of bag)

1mg in 500mL NS

2mcg/mL

what is the dosage for pediatric vasopressor epi drip and how do you set up the bag

1mg/500mL NS

0.1-1mcg/kg/min IV/IO

What is the indication for push dose epi 2

hypotension

bradycardia

What is the dosage for push dose epi

5-20mcg

How do you reconstitute push dose epi and from what vial do you pull from. What is the reconstituted concentration

0.1mg from 1mg/10mL vial

+ 9mL NS

10mcg/mL

What is the RPT dose and time for push dose epi

5-20mcg

q2-5min

What is the weight cutoff for push dose epi

don’t use for less than 50kg

What is the indication for cardiac epi

Cardiac arrest

What is the dosage for cardiac epi

1mg IVP

What is the RPT dose and time for cardiac epi

1mg q3-5 min

What are 4 contraindications for respiratory epi

tachycardia

hypertension

arrythmia

chest pain

What is the indication for dphenhydramine (Benadryl)

Allergy

Anaphylaxis

What is the dosage for diphenhydramine (benadryl)

25-50mg IV IO PO

What is the class for diphenhydramine (benadryl) 2 things

Antihistamine

H1 blocker

What is the MOA for diphenhydramine (benadryl) 3

H1 receptor antagonist

sedative and anticholinergetic

Reverses EPS

What is the max dose and time for diphenhydramine (benadryl)

Max 50mg

What is the duration for diphenhydramine (benadryl)

4-8hr

What are 2 considerations to think of with diphenhydramine (benadryl)

Minor sedation

Pediatric paradoxal reactions

What is the pediatric dose for diphenhydramine (benadryl)

1mg/kg

What is the duration of anaphylaxis epi

5-15min

What is the duration of respiratory epi

5-15 min

What is the duration of push dose epi

1-2min

What is the duration of cardiac epi

3-5min

What is the indication for methylprednisalone (solumedrol) 3

Anaphylaxis

Asthma

Allergy

What class is methylprednisolone (solumedrol)

Systematic corticosteroid

What is the dose for methylprednisolone (solumedrol)

125mg IV IO

What is the MOA for methylprednisolone (solumedrol)

Synthetic glococorticoid that supresses inflammation

What is the duration for methylprednisolone (solu medrol)

4hrs

Can you repeat solu medrol

no

What are 3 contraindications for methylprednisolone (solu medrol)

head Tx

systematic fungal infection

GI bleed

What is the pediatric dosage for methylprednisolone (solumedrol)

1-2mg/kg

What is the indication for acetaminophen 2

fever

mild to moderate pain

What is the class for acetaminophen 2

antipyretic

analgesic

What is the MOA for acetaminophen

Unclear

Works centrally to reduce fever and pain pathways

What is the dosage and repeat time for acetaminophen

1000mg PO

q8h

What is the pediatric dose for acetaminophen and RPT time

15mg/kg

q4-6h

What is the adult max dose daily for acetaminophen

4g

Why do you caution use of acetaminophen and percocet

percocet is a combination drug

What class is acetazolamide 2

diuretic

carbonic anhydrase inhibitor

What is the MOA for acetazolamide 3

Inhibits carbonic anhydrase

Decreases H+ renal secretion

Increases Na, K, bicarb, h20 secretion

What is the prophylactic dose for acetazolamide

125mg PO

What is the treatment dose for acetazolamide

250mg PO

What is the max dose for acetazolamide and RPT time

250mg

q12h

What is the pediatric dose for acetazolamide

2.5mg/kg PO

What is the indication for acetazolamide

Acute mountain sickness

What is one contraindication for acetazolamide

Sulfa allergy

What are 3 adverse effects of acetazolamide

parasthesia

polyuria

dehydration

What is the duration for acetazolamide

4-12hr

What class is dexamethasone

systematic cortico steroid

What is the MOA for dexamethasone 3

Long acting

decreases inflammation

supresses normal immune response

What is the acute mountain sickness dose for dexamethasone

4mg PO

What is the HACE dose for dexamethasone

8mg IV IO PO

then 4mg q6h

What is the pediatric dose for dexamethasone

0.15mg/kg IV IO PO

What is the indication for dexamethasone 2

HACE

Severe acute mountain sickness

What are 4 considerations with dexamethasone (adverse effects and consideratioin)

descent is required

Restlessness

hyperglycemia

hypertension

What is the RPT time for dexamethasone

q6h

What is the duration of dexamethasone

24-72h

What class is Nifedipine

Calcium channel blocker

What is the MOA for Nifedipine 4

Inhibit Ca movement

vasodilation

reduce preload and afterload

no AV effect

What is the dosage for nifedipine ER and RPT time

30mg PO q12h

What is the normal release dose for nifedipine and RPT time

20mg PO q8h

What is the pediatric dose for nifedipine and RPT time

0.5mg/kg PO q8h

not recommended

What is the indication for nifedipine

HAPE

What are 2 considerations when using nifedipine

Descent is required

avoid hypotension

What is the duration for nifedipine

6-8h

What class is naloxone (narcan) 2

Antidote

Opioid Antagonist

What is the MOA for Naloxone (narcan)

Compettive opioid receptor inhibitor

What is the dose for naloxone

0.4-2mg IV IO IM IN

What is the pediatric dose for naloxone

0.1mg/kg IV IO IM IN up to adult dose

What is the indication for naloxone 2

respiratory depression from opioids

Unknown coma

What are 2 considerations when using naloxone

Use minimum needed

Caution in opioid dependents and neonates

What is the duration for naloxone

20-60 minutes

What is the RPT time and max dosage for naloxone

q2-3min

max 10mg

What class is flumazenil 2

Antidote

GABA (benzo) antagonist

What is the MOA for flumazenil

Inhibits activity on benzo receptor site on GABA benzo receptor complex

What is the dose for flumazenil 1st and 2nd

1st 0.2mg IV over 30 seconds

2nd 0.3mg over 30 seconds

What is the pediatric dose for flumazenil

0.01mg/kg up to adult dose

What is the indication for flumazenil

Reverse respiratory depression and sedation of benzo od

What are 3 contraindications for flumazeil

Chronic benzo use

TCA overdose

Seizure prone

What is the RPT dose for flumazenil and time

0.5mg over 30s

q1m

What is the max dose for flumazenil

3mg

What class is pralidoxme chloride (2-Pam) (duodote ATNAA) 2

Antidote

Cholinesterase reactivator

What is the MOA for pralidoxime chloride (2-pam)(duodote ATNAA)

reactivate acetylcholinesterase that has been inactiviated by poisoning

What is the dose for pralidoxime chloride (2pam)(duodote ATNAA)

600mg IM

What is the pediatric dose for pralidoxime chloride (2pam)(duodote ATNAA) and MAX dose

15mg/kg IM

max 600mgW

What is the indication for pralidoxime chloride (2pam)(duodote ATNAA) 2

Organophosphate

Nerve agent