PC 2 mod 2.2 lec 7 (beta-lactam med chem)

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Last updated 3:32 AM on 8/15/26
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10 Terms

1
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penicillin

example of

<p>example of</p>
2
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cephalosporin

example of

<p>example of</p>
3
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carbapenem

example of

<p>example of</p>
4
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- amide

- stability

- breadth of spectrum

_______ is attached to nitrogen on beta-lactam ring which is critical for ______ and ______

5
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methicillin

first semi-synthetic penicillin approved for clinical use resistant to penicillinase

6
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electron withdrawing groups

_______ groups can be added to penicillins to make them better absorbed in acid

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steric bulk

increasing ______ adjacent to amide in beta-lactam makes it more resistant to beta-lactamase

8
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- fungus

- fungus

- bacteria

penicillin was found in....

cephalosporin was found in...

carbapenem was found in....

9
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- amine

- dimer

______ of carbapenems was a problem for stability, and was able to form ______

10
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cap

amines of carbapenems needed _____ for stability