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where does glycolysis take place?
cytoplasm
first step of glycolysis?
glucose phosphorylated using 2 molecules of ATP, forming hexose bisphosphate
second step of glycolysis?
hexose bisphosphate splits into 2 molecules of triose phosphate (3 carbon sugar)
why does the phosphorylated glucose split?
because it is very reactive
third step of glycolysis?
each TP oxidised (lose H)
by carrier molecule NAD which is reduced (gain H)
which becomes NADH
fourth step of glycolysis?
4 ATP molecules produced via substrate-level phosphorylation (2 per TP)
net gain of 2 ATP
final step of glycolysis?
substrate-level phosphorylation of TP produces 2 molecules of pyruvate
where does links reaction take place?
mitochondrial matrix
first step of the links reaction?
pyruvate is transported to the mitochondrial matrix
second step of the links reaction?
pyruvate is decarboxylated, realising a CO2 molecule
third step of the links reaction?
reaming 2 carbon molecule then oxidised by NAD which is reduced, becoming NADH
forming acetate
fourth step of the links reaction?
acetate combines with coenzyme A
forming acetylcoenzyme A, which then enters the krebs cycle
link reaction process equation?
private → acetylcoA + NADH + CO2
first step of kreb cycle?
2C acetyl co enzyme A combines with 4C molecule to form 6C molecule
second step of kreb cycle?
6C molecule loses CO2 + H to produce 4C molecule + single mol of ATP due to substrate level phosphorylation
third step of kreb cycle?
4C molecule now combines w/ new molecule of acetyl coenzyme A to begin the cycle again