Week 17 - Malaria, Piroplasma Myxozoan

Malarias

Development is similar to that of coccidia

vertebrates

malarias schizogony and gametogony occurs in

blood sucking insects

malarias sporogony occurs in

Plasmodium, Haemoproteus, Leucocytozoon

genera under Malaria

RBC and endothelial cells of inner organs (spleen, liver, lung, brain etc)

Genus Plasmodium Schizogony occurs in

Anopheline mosquito

Genus Plasmodium Sexual cycle occurs in blood sucking insect particularly ___ in mammals

Culicine spp.

Genus Plasmodium Sexual cycle occurs in blood sucking insect particularly ___ in BIRDS

hemozoin

the pigment granules present in genus plasmodium

False

T/F; Plasmodium gallinaceum has an occurrence in Phil.

True

T/F: Plasmodium juxtanucleare has an occurrence in Phil.

Plasmodium gallinaceum

gamounts are round and irregular

Plasmodium juxtanucleare

gamounts are elongated and pyriform

displaced

Host RBC nucleus of Plasmodium gallinaceum are

Plasmodium juxtanucleare

Host RBC nucleus are not displaced

Plasmodium falciparum

causative agent of "malignant tertian malaria

HUMAN Plasmodium/malignant tertian malaria

Most malignant form of human malaria

Plasmodium Knowlesi

causative agent of Quotidian malaria

Quotidian malaria

fevers that spike every 24 hours

Plasmodium vivax

causative agent of Benign Tertian malaria

Plasmodium malariae

causative agent of Quartan malaria

3

P. Malariae; schizogony takes __days

Mild tertian malaria

Plasmodium ovale causes

birds, turtles, and lizards

Haemoproteus hosts

vascular endothelial cells (organs)

Haemoproteus schizogony

horseshoe-shaped

Gametocytes are _ in RBC's

Culicoides, Hippoboscidae, & Chrysops

vectors of Haemoproteus

Haemoproteus columbae and H. danilewskii

__ and __ cause Pigeon MAlaria

Pigeons (squabs)

Host of Haemoproteus columbae and H. danilewskii

hippoboscid flies and biting midges

Vector of Haemoproteus columbae and H. danilewskii

False

T/F: Haemoproteus columbae and H. danilewskii are not prevalent in the Phil.

chicken

host of Leucocytozoon caulleryi

ducks and geese

host of Leucocytozoon simondi

Turkey

host of Leucocytozoon smithi

Culicoides

vector of Leucocytozoon caulleryi

Simulium

vector of Leucocytozoon smithi

Simulium

vector of Leucocytozoon simondi

round, oval, ellipsoidal

shape of Leucocytozoon caulleryi

spindle

shape of Leucocytozoon simondi

elongate spindle

shape of Leucocytozoon smithi

endothelial cells of various tissues

location where schizogony take places (genus Leucocytozoon)

rbc and wbc

location where gametogony take places (genus Leucocytozoon)

enlarged, distorted and damaged

what happens to rbc and wbc when gametogony takes place

lower monkeys (ex. lemurs), fruit bats, and squirrels of the Old World

host of Genus hepatocystis

hepatocytes

where schizogony of Genus Hepatocystis takes place

2 months

duration of schizogony of Hepatocystis

Merocysts (large schizont) -> RBC -> gametocyte

life cycle(?) of Hepatocystis

Culicoides

vector of Hepatocystis

Piroplasmosis/ Babesiosis

Genus Babesia/Piroplasm causes

erythrocytes

where Babesia multiply

intestinal lumen of the tick

where sexual conjugation of Babesia takes place

epithelium of the tick's intestinal wall

where sporogony of Babesia takes place

Babesia bigemina

bovine also zebu, water buffalo;Texas cattle fever, redwater fever, or hemoglobinuria

Babesia microti

infections in humans

Babesia bovis

in cattle also in in deer and stag in Europe, Russia, and Africa

Babesia berbera

in Russia, North Africa, and the Middle East

Babesia divergens

cattle,human in western and central Europe

Babesia argentina

in South America, Central America, and Australia

Babesia major

in cattle in North Africa, Europe, and Russia.

Babesia ovis

in sheep and goat

Babesia canis

domestic dog

Babesia trautmanni

pigs, warthogs

Babesia caballi, Babesia equi

horse, donkey and mule

lymphocytes

in Family Theileriidae, schizogony takes place in

Theileria parva

RBC, lymphocytes, and endothelial cells)

- Theilerosis called East Coast fever in cattle, zebu, and Cape buffalo

=one of the most important diseases of cattle

Theileria annulata

(spp of Theileriidae) bovine, zebu, water buffalo

Theileria lawrenci

buffalo, cattle and water buffalo

- causes corridor disease

Theileria cervi

white-tailed deer

Theileria tarandi

reindeer

Theileria hirci

sheep and goat

Theileria ovis

sheep and goat

Theileria camelensis

camel

vertebrate macrophage

Genus Cytauxzoon, schozogony takes place in

Cytauxzoon felis

fatal tick-transmitted (Dermacentor variabilis/Amblyomma americanum) piroplasm in cats

safety pin, Maltese cross

Cytauxzoon felis, in lower number-appears as __ and __ in erythrocytes

Wright's- or Giemsa-stained

____ blood smear reveal 1- to 2-mm organisms with light blue cytoplasm and dark red nucleus in the erythrocytes

light blue, dark red

Wright's- or Giemsa-stained blood smears reveal 1- to 2-mm organisms with __cytoplasm and __ nucleus in the erythrocytes

Cytauxzoonosis

disease cause by Cytauxzoon felis

clinical signs of infected with Cytauxzoonosis

anorexia, altered level of consciousness, seizures, lethargy, icterus, mucous membrane pallor, pyrexia, dyspnea, splenomegaly, and hepatomegal

invertebrates

(Subphylum Myxozoa Class Microsporea)

Life cycles - sexual proliferative cycles in

vertebrates

asexual proliferative cycles in