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Immunohematology II
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IgG immunoglobulins:
can cross the placenta from mother to fetus
Human blood groups were discovered around the year 1900 by:
K. Landsteiner
Ulex europaeus is:
a lectin with anti-H specificity
React best at body temperature (37 degrees Celsius), ability to cross the placental barrier, monomer structure...these are all good descriptor terms for which subclass of immunoglobulin?
IgG
A donor tested negative using commercial Anti-D reagent. The weak D test was positive. How should the unit be labeled?
D-positive
Which of the following is NOT true of ABO antibodies?
They are present at birth.
The alloantibodies produced by a patient upon exposure to a blood group antigen he/she lacks is an example of _________ immunity.
adaptive
Composed of proteins that cross the RBC membrane multiple times, not expressed on tissues or found in secretions...these statements describe ____ antigens.
Rh
A blood donor has the following genotype: hh, AB.
What is his red blood cell phenotype?
O
Group A2 constitutes approximately what percentage of group A individuals?
20%
On which type of person is weak D testing required?
blood donors
The greatest amount of H antigen is present on red cells of group:
O
Which statement regarding Rh antibodies is false?
They are naturally occurring.
ABO genes code for:
glycosyltransferases
A term used when two of the same alleles of a gene are inherited from each parent is:
homozygous
The enzyme responsible for adding H antigen to the red cell membrane is alpha-
L-fucosyl transferase