Edexcel IGCSE Biology - Topic 2
what are stem cells?
undifferentiated cells
can produce many more cells of the same type (undifferentiated stem cells)
can undergo differentiation
embryonic stem cells
found in inside layer of an embryo
undifferentiated
can produce all the different types of specialised cells in the body
adult stem cells
found in bone marrow
mainly differentiates into cells of the blood
found in skin
differentiates into cells found in layers of skin
found in organs (liver, brain)
differentiates into cells in particular orgain it is found in
found in umbilical cord blood
differentiates into cells of the blood, muscle tissue and nerve tissue
meristem cells
found in the tips of roots and shoots in plants
fully undifferentiated
one stem cell = ability to produce whole new plant
what is stem cell therapy?
used in medicine
stem cells are injected into a damaged area and divide to form differentiated replacement cells
this allows the organ to continue functioning normally
sources of therapeutic stem cells: embryonic stem cells, umbilical cord stem cells
what are the advantages of using stem cells?
could be used to cure many diseases in the future (diabetes type 1, paralysis)
organs can be grown from patients own stem cells - reduces risk of rejection by body
adult stem cells used successfully in variety of treatments
what are the disadvantages of stem cells in medicine?
stem cells cultured in labs could become infected
risk of culture stem cells accumalating mutations = risk of cancer
low number of stem cell donors
ethical issue of using embryonic stem cells from IVF - is it right to use them?
embryonic stem cells/umbilical cord stem cells = expensive